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Article: Upper gastrointestinal evaluation of Chinese patients with non-cardiac chest pain

TitleUpper gastrointestinal evaluation of Chinese patients with non-cardiac chest pain
Authors
Issue Date2002
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
Citation
Alimentary Pharmacology And Therapeutics, 2002, v. 16 n. 3, p. 465-471 How to Cite?
AbstractAims: To test the usefulness of upper gastrointestinal investigations and quality of life assessment in Chinese patients with non-cardiac chest pain. Methods: Seventy-eight consecutive patients with noncardiac chest pain underwent upper endoscopy. Eight patients had upper gastrointestinal pathology (10%). The remaining 70 patients received acid perfusion test, oesophageal manometry and 24-h ambulatory oesophageal pH (n = 65)/manometry (n = 61), and the results were compared with those of healthy controls (n = 20). Symptoms and quality of life (SF-36) were assessed by standard validated questionnaire. Results: Significant acid reflux symptoms were present in five (5/70. 7%) patients. Abnormal 24-h oesophageal pH, indicating gastro-oesophageal reflux, was found in 19 (19/65, 29%) patients. The percentage of simultaneous contractions was higher and the percentage peristalsis was lower in patients with non-cardiac chest pain when compared with normal subjects by 24-h ambulatory manometry. Patients with non-cardiac chest pain had a lower SF-36 score when compared to controls. Conclusions: Typical acid reflux symptoms are uncommon in Chinese patients with non-cardiac chest pain, but abnormal 24-h pH results, indicating gastro-oesophageal reflux, were found in 29% of patients. Ineffective contractions were more frequently found in patients with non-cardiac chest pain by 24-h ambulatory manometry, which may have a bearing on the impaired quality of life in such patients. Upper gastrointestinal investigations are useful for the evaluation of Chinese patients with non-cardiac chest pain.
Persistent Identifierhttp://hdl.handle.net/10722/78314
ISSN
2015 Impact Factor: 6.32
2015 SCImago Journal Rankings: 2.833
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, WMen_HK
dc.contributor.authorLai, KCen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorHu, WHCen_HK
dc.contributor.authorChen, WHen_HK
dc.contributor.authorWong, BCYen_HK
dc.contributor.authorHui, WMen_HK
dc.contributor.authorWong, YHen_HK
dc.contributor.authorXia, HHXen_HK
dc.contributor.authorLam, SKen_HK
dc.date.accessioned2010-09-06T07:41:31Z-
dc.date.available2010-09-06T07:41:31Z-
dc.date.issued2002en_HK
dc.identifier.citationAlimentary Pharmacology And Therapeutics, 2002, v. 16 n. 3, p. 465-471en_HK
dc.identifier.issn0269-2813en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78314-
dc.description.abstractAims: To test the usefulness of upper gastrointestinal investigations and quality of life assessment in Chinese patients with non-cardiac chest pain. Methods: Seventy-eight consecutive patients with noncardiac chest pain underwent upper endoscopy. Eight patients had upper gastrointestinal pathology (10%). The remaining 70 patients received acid perfusion test, oesophageal manometry and 24-h ambulatory oesophageal pH (n = 65)/manometry (n = 61), and the results were compared with those of healthy controls (n = 20). Symptoms and quality of life (SF-36) were assessed by standard validated questionnaire. Results: Significant acid reflux symptoms were present in five (5/70. 7%) patients. Abnormal 24-h oesophageal pH, indicating gastro-oesophageal reflux, was found in 19 (19/65, 29%) patients. The percentage of simultaneous contractions was higher and the percentage peristalsis was lower in patients with non-cardiac chest pain when compared with normal subjects by 24-h ambulatory manometry. Patients with non-cardiac chest pain had a lower SF-36 score when compared to controls. Conclusions: Typical acid reflux symptoms are uncommon in Chinese patients with non-cardiac chest pain, but abnormal 24-h pH results, indicating gastro-oesophageal reflux, were found in 29% of patients. Ineffective contractions were more frequently found in patients with non-cardiac chest pain by 24-h ambulatory manometry, which may have a bearing on the impaired quality of life in such patients. Upper gastrointestinal investigations are useful for the evaluation of Chinese patients with non-cardiac chest pain.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APTen_HK
dc.relation.ispartofAlimentary Pharmacology and Therapeuticsen_HK
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshChest Pain - diagnosis - etiologyen_HK
dc.subject.meshChinaen_HK
dc.subject.meshDiagnosis, Differentialen_HK
dc.subject.meshEndoscopy, Gastrointestinalen_HK
dc.subject.meshEsophagitis, Peptic - diagnosisen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGastroesophageal Reflux - diagnosisen_HK
dc.subject.meshHeartburn - diagnosisen_HK
dc.subject.meshHumansen_HK
dc.subject.meshHydrogen-Ion Concentrationen_HK
dc.subject.meshMaleen_HK
dc.subject.meshManometryen_HK
dc.subject.meshMass Screening - methodsen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshQuality of Lifeen_HK
dc.subject.meshQuestionnairesen_HK
dc.titleUpper gastrointestinal evaluation of Chinese patients with non-cardiac chest painen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-2813&volume=16&issue=3&spage=465&epage=471&date=2002&atitle=Upper+gastrointestinal+evaluation+of+Chinese+Patients+with+non-cardiac+chest+painen_HK
dc.identifier.emailWong, BCY:bcywong@hku.hken_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1046/j.1365-2036.2002.01217.xen_HK
dc.identifier.pmid11876699-
dc.identifier.scopuseid_2-s2.0-0036185665en_HK
dc.identifier.hkuros72108en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036185665&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue3en_HK
dc.identifier.spage465en_HK
dc.identifier.epage471en_HK
dc.identifier.isiWOS:000174423800015-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, WM=7403972413en_HK
dc.identifier.scopusauthoridLai, KC=7402135595en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK
dc.identifier.scopusauthoridHu, WHC=25932937100en_HK
dc.identifier.scopusauthoridChen, WH=7409637978en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK
dc.identifier.scopusauthoridHui, WM=7103196477en_HK
dc.identifier.scopusauthoridWong, YH=24073787400en_HK
dc.identifier.scopusauthoridXia, HHX=8757161400en_HK
dc.identifier.scopusauthoridLam, SK=7402279473en_HK

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