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Article: Ethnic and geographical differences in systemic lupus erythematosus: An overview

TitleEthnic and geographical differences in systemic lupus erythematosus: An overview
Authors
KeywordsAutoimmunity
Connective tissue disease
Epidemiology
Issue Date2006
PublisherSage Publications Ltd. The Journal's web site is located at http://lup.sagepub.com
Citation
Lupus, 2006, v. 15 n. 11, p. 715-719 How to Cite?
AbstractSystemic lupus erythematosus (SLE) is one of the most heterogeneous autoimmune disorders known. There is production of a variety of autoantibodies and patients present with a wide range of symptoms due to multiple organ involvement by the disease process. The underlying cause is not fully understood but it may involve genetic and environmental factors. It is interesting to note that while SLE is found worldwide, it is more commonly found in some countries, and within a country certain ethnic groups appear to be more susceptible to develop this condition than others. Additionally, the presentation and course of SLE appear highly variable between patients of different ethnic origins. For example, African-Americans and Orientals are believed to have a more severe disease than Caucasian whites. But are these ethnic and geographical differences real? If yes, they may provide investigators insight into the underlying pathoaetiology of this condition and pave the way to future research directions in lupus. © 2006 SAGE Publications.
Persistent Identifierhttp://hdl.handle.net/10722/78136
ISSN
2023 Impact Factor: 1.9
2023 SCImago Journal Rankings: 0.812
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLau, CSen_HK
dc.contributor.authorYin, Gen_HK
dc.contributor.authorMok, MYen_HK
dc.date.accessioned2010-09-06T07:39:34Z-
dc.date.available2010-09-06T07:39:34Z-
dc.date.issued2006en_HK
dc.identifier.citationLupus, 2006, v. 15 n. 11, p. 715-719en_HK
dc.identifier.issn0961-2033en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78136-
dc.description.abstractSystemic lupus erythematosus (SLE) is one of the most heterogeneous autoimmune disorders known. There is production of a variety of autoantibodies and patients present with a wide range of symptoms due to multiple organ involvement by the disease process. The underlying cause is not fully understood but it may involve genetic and environmental factors. It is interesting to note that while SLE is found worldwide, it is more commonly found in some countries, and within a country certain ethnic groups appear to be more susceptible to develop this condition than others. Additionally, the presentation and course of SLE appear highly variable between patients of different ethnic origins. For example, African-Americans and Orientals are believed to have a more severe disease than Caucasian whites. But are these ethnic and geographical differences real? If yes, they may provide investigators insight into the underlying pathoaetiology of this condition and pave the way to future research directions in lupus. © 2006 SAGE Publications.en_HK
dc.languageengen_HK
dc.publisherSage Publications Ltd. The Journal's web site is located at http://lup.sagepub.comen_HK
dc.relation.ispartofLupusen_HK
dc.rightsLupus. Copyright © Sage Publications Ltd.en_HK
dc.subjectAutoimmunity-
dc.subjectConnective tissue disease-
dc.subjectEpidemiology-
dc.subject.meshAnemia, Hemolytic, Autoimmune - ethnology - etiologyen_HK
dc.subject.meshContinental Population Groups - geneticsen_HK
dc.subject.meshEthnic Groups - geneticsen_HK
dc.subject.meshGenetic Predisposition to Disease - ethnologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshKidney Diseases - ethnology - etiologyen_HK
dc.subject.meshLupus Erythematosus, Discoid - ethnology - etiologyen_HK
dc.subject.meshLupus Erythematosus, Systemic - complications - diagnosis - epidemiology - genetics - immunologyen_HK
dc.subject.meshPrognosisen_HK
dc.subject.meshSurvival Rateen_HK
dc.subject.meshThrombosis - ethnology - etiologyen_HK
dc.titleEthnic and geographical differences in systemic lupus erythematosus: An overviewen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0961-2033&volume=15&issue=11&spage=715&epage=719&date=2006&atitle=Ethnic+and+Geographical+Differences+in+Systemic+Lupus+Erythematosus:+An+Overviewen_HK
dc.identifier.emailLau, CS:cslau@hku.hken_HK
dc.identifier.emailMok, MY:temy@hkucc.hku.hken_HK
dc.identifier.authorityLau, CS=rp01348en_HK
dc.identifier.authorityMok, MY=rp00490en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1177/0961203306072311en_HK
dc.identifier.pmid17153840-
dc.identifier.scopuseid_2-s2.0-39049185771en_HK
dc.identifier.hkuros134340en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-39049185771&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue11en_HK
dc.identifier.spage715en_HK
dc.identifier.epage719en_HK
dc.identifier.isiWOS:000242321600002-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLau, CS=14035682100en_HK
dc.identifier.scopusauthoridYin, G=23500677100en_HK
dc.identifier.scopusauthoridMok, MY=7006024184en_HK
dc.identifier.issnl0961-2033-

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