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Article: Hypertension and cardiac arrhythmias: A review of the epidemiology, pathophysiology and clinical implications

TitleHypertension and cardiac arrhythmias: A review of the epidemiology, pathophysiology and clinical implications
Authors
Issue Date2008
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/jhh
Citation
Journal Of Human Hypertension, 2008, v. 22 n. 6, p. 380-388 How to Cite?
AbstractHypertension is commonly associated with cardiac arrhythmias in patients with and without concomitant cardiovascular disease. Experimental and epidemiological studies have demonstrated potential links between hypertension and atrial and ventricular arrhythmias, although the underlying pathophysiological mechanism remains unclear. Nonetheless, the importance of hypertension as a cause of atrial and ventricular arrhythmias is not well recognized. In particular, the occurrence of left ventricular hypertrophy is a strong predictor for the development of AF, ventricular ectopy and sudden cardiac death. Recent prospective clinical trials reveal that antihypertensive therapy may delay or prevent the occurrence of cardiac arrhythmias and sudden cardiac death in patients with hypertension. Although antihypertensive agents that block the renin-angiotensin-aldosterone system appear to protect against cardiac arrhythmias, this needs to be confirmed by current ongoing clinical trials.
Persistent Identifierhttp://hdl.handle.net/10722/78106
ISSN
2015 Impact Factor: 2.833
2015 SCImago Journal Rankings: 1.167
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYiu, KHen_HK
dc.contributor.authorTse, HFen_HK
dc.date.accessioned2010-09-06T07:39:13Z-
dc.date.available2010-09-06T07:39:13Z-
dc.date.issued2008en_HK
dc.identifier.citationJournal Of Human Hypertension, 2008, v. 22 n. 6, p. 380-388en_HK
dc.identifier.issn0950-9240en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78106-
dc.description.abstractHypertension is commonly associated with cardiac arrhythmias in patients with and without concomitant cardiovascular disease. Experimental and epidemiological studies have demonstrated potential links between hypertension and atrial and ventricular arrhythmias, although the underlying pathophysiological mechanism remains unclear. Nonetheless, the importance of hypertension as a cause of atrial and ventricular arrhythmias is not well recognized. In particular, the occurrence of left ventricular hypertrophy is a strong predictor for the development of AF, ventricular ectopy and sudden cardiac death. Recent prospective clinical trials reveal that antihypertensive therapy may delay or prevent the occurrence of cardiac arrhythmias and sudden cardiac death in patients with hypertension. Although antihypertensive agents that block the renin-angiotensin-aldosterone system appear to protect against cardiac arrhythmias, this needs to be confirmed by current ongoing clinical trials.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/jhhen_HK
dc.relation.ispartofJournal of Human Hypertensionen_HK
dc.subject.meshAngiotensin II Type 1 Receptor Blockers - therapeutic useen_HK
dc.subject.meshAngiotensin-Converting Enzyme Inhibitors - therapeutic useen_HK
dc.subject.meshArrhythmias, Cardiac - epidemiology - etiology - physiopathology - prevention & controlen_HK
dc.subject.meshDeath, Sudden, Cardiac - etiologyen_HK
dc.subject.meshHemodynamicsen_HK
dc.subject.meshHumansen_HK
dc.subject.meshHypertension - complications - drug therapyen_HK
dc.subject.meshHypertrophy, Left Ventricular - complicationsen_HK
dc.titleHypertension and cardiac arrhythmias: A review of the epidemiology, pathophysiology and clinical implicationsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0950-9240&volume=22&spage=380&epage=8&date=2008&atitle=Hypertension+and+cardiac+arrhythmias:+A+review+of+the+epidemiology,+pathophysiology+and+clinical+implications.en_HK
dc.identifier.emailYiu, KH:khkyiu@hku.hken_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.authorityYiu, KH=rp01490en_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/jhh.2008.10en_HK
dc.identifier.pmid18337759-
dc.identifier.scopuseid_2-s2.0-44149094528en_HK
dc.identifier.hkuros140853en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-44149094528&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue6en_HK
dc.identifier.spage380en_HK
dc.identifier.epage388en_HK
dc.identifier.isiWOS:000255897500002-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridYiu, KH=35172267800en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.citeulike2528101-

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