File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: An Indolent Case of Severe Acute Respiratory Syndrome

TitleAn Indolent Case of Severe Acute Respiratory Syndrome
Authors
KeywordsBone marrow transplantation
Clinical presentation
Severe acute respiratory syndrome
Issue Date2004
PublisherAmerican Thoracic Society. The Journal's web site is located at http://ajrccm.atsjournals.org
Citation
American Journal Of Respiratory And Critical Care Medicine, 2004, v. 169 n. 1, p. 125-128 How to Cite?
AbstractSevere acute respiratory syndrome (SARS) is a highly contagious and typically rapidly progressive form of atypical pneumonia, which spread from Asia to many parts of the world in early 2003. Clinical diagnosis of SARS requires the presence of unremitting fever and progressive pneumonia despite antibiotic therapy, particularly in the presence of lymphopenia and raised transaminase levels. We report the case of a woman who had undergone a successful allogeneic bone marrow transplant for acute myeloid leukemia. She presented initially with fever and a normal chest radiograph. Her indolent clinical course of SARS was punctuated by resolution of fever, but there was progressive radiologic deterioration and increasing serum antibody titer against SARS coronavirus. Treatment with oral prednisolone and ribavirin normalized her lymphopenia, altered transaminases, chest radiograph and high-resolution computed tomography appearances rapidly. Our experience should alert other clinicians in recognizing this atypical indolent presentation of SARS, to protect health care workers and the community at large and to ensure that these patients are properly treated.
Persistent Identifierhttp://hdl.handle.net/10722/77915
ISSN
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, MFen_HK
dc.contributor.authorOoi, GCen_HK
dc.contributor.authorLam, Ben_HK
dc.contributor.authorHo, JCen_HK
dc.contributor.authorSeto, WHen_HK
dc.contributor.authorHo, PLen_HK
dc.contributor.authorWong, PCen_HK
dc.contributor.authorLiang, Ren_HK
dc.contributor.authorLam, WKen_HK
dc.contributor.authorTsang, KWen_HK
dc.date.accessioned2010-09-06T07:37:09Z-
dc.date.available2010-09-06T07:37:09Z-
dc.date.issued2004en_HK
dc.identifier.citationAmerican Journal Of Respiratory And Critical Care Medicine, 2004, v. 169 n. 1, p. 125-128en_HK
dc.identifier.issn0003-0805en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77915-
dc.description.abstractSevere acute respiratory syndrome (SARS) is a highly contagious and typically rapidly progressive form of atypical pneumonia, which spread from Asia to many parts of the world in early 2003. Clinical diagnosis of SARS requires the presence of unremitting fever and progressive pneumonia despite antibiotic therapy, particularly in the presence of lymphopenia and raised transaminase levels. We report the case of a woman who had undergone a successful allogeneic bone marrow transplant for acute myeloid leukemia. She presented initially with fever and a normal chest radiograph. Her indolent clinical course of SARS was punctuated by resolution of fever, but there was progressive radiologic deterioration and increasing serum antibody titer against SARS coronavirus. Treatment with oral prednisolone and ribavirin normalized her lymphopenia, altered transaminases, chest radiograph and high-resolution computed tomography appearances rapidly. Our experience should alert other clinicians in recognizing this atypical indolent presentation of SARS, to protect health care workers and the community at large and to ensure that these patients are properly treated.en_HK
dc.languageengen_HK
dc.publisherAmerican Thoracic Society. The Journal's web site is located at http://ajrccm.atsjournals.orgen_HK
dc.relation.ispartofAmerican Journal of Respiratory and Critical Care Medicineen_HK
dc.subjectBone marrow transplantationen_HK
dc.subjectClinical presentationen_HK
dc.subjectSevere acute respiratory syndromeen_HK
dc.subject.meshAnti-Bacterial Agentsen_HK
dc.subject.meshBone Marrow Transplantation - immunologyen_HK
dc.subject.meshDrug Therapy, Combination - administration & dosageen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshImmunocompromised Hosten_HK
dc.subject.meshLeukemia, Myeloid, Acute - diagnosis - therapyen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshRadiography, Thoracicen_HK
dc.subject.meshRisk Assessmenten_HK
dc.subject.meshSARS Virus - isolation & purificationen_HK
dc.subject.meshSevere Acute Respiratory Syndrome - diagnosis - drug therapyen_HK
dc.subject.meshSeverity of Illness Indexen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.titleAn Indolent Case of Severe Acute Respiratory Syndromeen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1073-449X&volume=169&issue=1&spage=125&epage=128&date=2004&atitle=An+indolent+case+of+severe+acute+respiratory+syndromeen_HK
dc.identifier.emailHo, JC:jhocm@hku.hken_HK
dc.identifier.emailHo, PL:plho@hkucc.hku.hken_HK
dc.identifier.emailLiang, R:rliang@hku.hken_HK
dc.identifier.authorityHo, JC=rp00258en_HK
dc.identifier.authorityHo, PL=rp00406en_HK
dc.identifier.authorityLiang, R=rp00345en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid14695107-
dc.identifier.scopuseid_2-s2.0-10744222237en_HK
dc.identifier.hkuros86280en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-10744222237&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume169en_HK
dc.identifier.issue1en_HK
dc.identifier.spage125en_HK
dc.identifier.epage128en_HK
dc.identifier.isiWOS:000187570500024-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLam, MF=35300050600en_HK
dc.identifier.scopusauthoridOoi, GC=7006176119en_HK
dc.identifier.scopusauthoridLam, B=9246012800en_HK
dc.identifier.scopusauthoridHo, JC=7402649981en_HK
dc.identifier.scopusauthoridSeto, WH=7005799377en_HK
dc.identifier.scopusauthoridHo, PL=7402211363en_HK
dc.identifier.scopusauthoridWong, PC=7403979916en_HK
dc.identifier.scopusauthoridLiang, R=26643224900en_HK
dc.identifier.scopusauthoridLam, WK=7203021937en_HK
dc.identifier.scopusauthoridTsang, KW=7201555024en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats