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Article: Comparison of endocardial activation times at effective and ineffective ablation sites within the pulmonary veins

TitleComparison of endocardial activation times at effective and ineffective ablation sites within the pulmonary veins
Authors
Issue Date2000
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1045-3873
Citation
Journal Of Cardiovascular Electrophysiology, 2000, v. 11 n. 2, p. 155-159 How to Cite?
AbstractIntroduction: Recent studies demonstrated that atrial arrhythmias may be generated within pulmonary veins. The purpose of this study was to compare the endocardial activation times at effective and ineffective ablation sites during radiofrequency catheter ablation of arrhythmias initiated or generated within pulmonary veins. Methods and Results: Twenty-one of 28 patients without structural heart disease underwent successful ablation of 23 arrhythmogenic foci within a pulmonary vein. Electrograms were recorded at 75 pulmonary venous sites and categorized into three groups: 23 successful ablation sites; 28 unsuccessful target sites within an arrhythmogenic pulmonary vein; and 24 sites within nonarrhythmogenic pulmonary veins. The endocardial activation time of premature depolarizations arising at successful target sites was significantly earlier than at other sites. During premature depolarizations, an endocardial activation time of -75 msec or earlier had a sensitivity of 83% and a specificity of 79% for identification of a successful ablation site. Endocardial activation times earlier than -100 msec were recorded only at successful ablation sites, and endocardial activation times later than -30 msec were recorded only at sites within nonarrhythmogenic pulmonary veins. The presence of a split potential during sinus rhythm or premature depolarizations was not a specific indicator of a successful ablation site. Conclusion: The endocardial activation times of premature depolarizations that arise within pulmonary veins and initiate atrial tachycardia/fibrillation are useful in identifying successful ablation sites.
Persistent Identifierhttp://hdl.handle.net/10722/77760
ISSN
2015 Impact Factor: 3.097
2015 SCImago Journal Rankings: 1.863
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTse, HFen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorKou, Wen_HK
dc.contributor.authorPelosi, Fen_HK
dc.contributor.authorOral, Hen_HK
dc.contributor.authorKim, Men_HK
dc.contributor.authorMichaud, GFen_HK
dc.contributor.authorKnight, BPen_HK
dc.contributor.authorMoscucci, Men_HK
dc.contributor.authorStrickberger, SAen_HK
dc.contributor.authorMorady, Fen_HK
dc.date.accessioned2010-09-06T07:35:26Z-
dc.date.available2010-09-06T07:35:26Z-
dc.date.issued2000en_HK
dc.identifier.citationJournal Of Cardiovascular Electrophysiology, 2000, v. 11 n. 2, p. 155-159en_HK
dc.identifier.issn1045-3873en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77760-
dc.description.abstractIntroduction: Recent studies demonstrated that atrial arrhythmias may be generated within pulmonary veins. The purpose of this study was to compare the endocardial activation times at effective and ineffective ablation sites during radiofrequency catheter ablation of arrhythmias initiated or generated within pulmonary veins. Methods and Results: Twenty-one of 28 patients without structural heart disease underwent successful ablation of 23 arrhythmogenic foci within a pulmonary vein. Electrograms were recorded at 75 pulmonary venous sites and categorized into three groups: 23 successful ablation sites; 28 unsuccessful target sites within an arrhythmogenic pulmonary vein; and 24 sites within nonarrhythmogenic pulmonary veins. The endocardial activation time of premature depolarizations arising at successful target sites was significantly earlier than at other sites. During premature depolarizations, an endocardial activation time of -75 msec or earlier had a sensitivity of 83% and a specificity of 79% for identification of a successful ablation site. Endocardial activation times earlier than -100 msec were recorded only at successful ablation sites, and endocardial activation times later than -30 msec were recorded only at sites within nonarrhythmogenic pulmonary veins. The presence of a split potential during sinus rhythm or premature depolarizations was not a specific indicator of a successful ablation site. Conclusion: The endocardial activation times of premature depolarizations that arise within pulmonary veins and initiate atrial tachycardia/fibrillation are useful in identifying successful ablation sites.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1045-3873en_HK
dc.relation.ispartofJournal of Cardiovascular Electrophysiologyen_HK
dc.subject.meshAdulten_HK
dc.subject.meshArrhythmias, Cardiac - physiopathology - surgeryen_HK
dc.subject.meshAtrial Fibrillation - physiopathology - surgeryen_HK
dc.subject.meshCatheter Ablationen_HK
dc.subject.meshElectrocardiographyen_HK
dc.subject.meshElectrocardiography, Ambulatoryen_HK
dc.subject.meshEndocardium - physiopathologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPulmonary Veins - physiopathology - surgeryen_HK
dc.subject.meshReaction Timeen_HK
dc.subject.meshTachycardia - physiopathology - surgeryen_HK
dc.titleComparison of endocardial activation times at effective and ineffective ablation sites within the pulmonary veinsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1045-3873&volume=11&issue=2&spage=155&epage=159&date=2000&atitle=Comparison+of+endocardial+activation+times+at+effective+and+ineffective+ablation+sites+within+the+pulmonary+veinsen_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10709709-
dc.identifier.scopuseid_2-s2.0-0033954286en_HK
dc.identifier.hkuros49717en_HK
dc.identifier.hkuros100599-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033954286&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume11en_HK
dc.identifier.issue2en_HK
dc.identifier.spage155en_HK
dc.identifier.epage159en_HK
dc.identifier.isiWOS:000085479100004-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK
dc.identifier.scopusauthoridKou, W=7007035393en_HK
dc.identifier.scopusauthoridPelosi, F=7004832991en_HK
dc.identifier.scopusauthoridOral, H=7006855160en_HK
dc.identifier.scopusauthoridKim, M=7406090815en_HK
dc.identifier.scopusauthoridMichaud, GF=7006729860en_HK
dc.identifier.scopusauthoridKnight, BP=7201940628en_HK
dc.identifier.scopusauthoridMoscucci, M=7004313718en_HK
dc.identifier.scopusauthoridStrickberger, SA=7005045293en_HK
dc.identifier.scopusauthoridMorady, F=35431764400en_HK

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