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Article: Lymphoma of the breast in Hong Kong Chinese

TitleLymphoma of the breast in Hong Kong Chinese
Authors
Issue Date1997
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/3182
Citation
Hematological Oncology, 1997, v. 15 n. 1, p. 33-38 How to Cite?
AbstractFourteen cases of non-Hodgkin's lymphoma presenting as breast mass from 1974 to 1996 were reviewed. The median age of presentation was 51 years. Three patients had bilateral disease and five had disseminated disease. A predominance of B cell disease of diffuse large cell histology was noted. Painless lumps were the most common presenting features and most patients were treated with excisional biopsy followed by combination chemotherapy. Radiotherapy was added to local bulky disease. Six patients, however, underwent mastectomy. The overall CR rate was 74 per cent, lasting a median of 32 months. At a median follow-up of 60 months five patients were still alive, one with relapsed disease. Salvage treatments for relapsed patients were uniformly poor. Compared to reported western series, our patients had more high grade disease, more T cell disease and more CNS relapses. Improvements in treatment may involve the use of fine needle aspiration of breast lesion prior to surgery, primary CNS prophylaxis in high grade disseminated disease and high dose chemotherapy with marrow/stem cell rescue in relapsed cases.
Persistent Identifierhttp://hdl.handle.net/10722/77739
ISSN
2015 Impact Factor: 3.494
2015 SCImago Journal Rankings: 0.767
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorAu, WYen_HK
dc.contributor.authorChan, ACLen_HK
dc.contributor.authorCnow, LWCen_HK
dc.contributor.authorLiang, Ren_HK
dc.date.accessioned2010-09-06T07:35:12Z-
dc.date.available2010-09-06T07:35:12Z-
dc.date.issued1997en_HK
dc.identifier.citationHematological Oncology, 1997, v. 15 n. 1, p. 33-38en_HK
dc.identifier.issn0278-0232en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77739-
dc.description.abstractFourteen cases of non-Hodgkin's lymphoma presenting as breast mass from 1974 to 1996 were reviewed. The median age of presentation was 51 years. Three patients had bilateral disease and five had disseminated disease. A predominance of B cell disease of diffuse large cell histology was noted. Painless lumps were the most common presenting features and most patients were treated with excisional biopsy followed by combination chemotherapy. Radiotherapy was added to local bulky disease. Six patients, however, underwent mastectomy. The overall CR rate was 74 per cent, lasting a median of 32 months. At a median follow-up of 60 months five patients were still alive, one with relapsed disease. Salvage treatments for relapsed patients were uniformly poor. Compared to reported western series, our patients had more high grade disease, more T cell disease and more CNS relapses. Improvements in treatment may involve the use of fine needle aspiration of breast lesion prior to surgery, primary CNS prophylaxis in high grade disseminated disease and high dose chemotherapy with marrow/stem cell rescue in relapsed cases.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/3182en_HK
dc.relation.ispartofHematological Oncologyen_HK
dc.rightsHematological Oncology. Copyright © John Wiley & Sons Ltd.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshBreast Neoplasms - pathologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLymphoma, Non-Hodgkin - drug therapy - pathology - surgeryen_HK
dc.subject.meshMiddle Ageden_HK
dc.titleLymphoma of the breast in Hong Kong Chineseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0278-0232&volume=15&spage=33&epage=38&date=1997&atitle=Lymphoma+of+the+breast+in+Hong+Kong+Chineseen_HK
dc.identifier.emailLiang, R:rliang@hku.hken_HK
dc.identifier.authorityLiang, R=rp00345en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/(SICI)1099-1069(199702)15:1<33::AID-HON595>3.0.CO;2-Ken_HK
dc.identifier.pmid9378471-
dc.identifier.scopuseid_2-s2.0-0030954855en_HK
dc.identifier.hkuros33102en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030954855&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue1en_HK
dc.identifier.spage33en_HK
dc.identifier.epage38en_HK
dc.identifier.isiWOS:A1997XY64900005-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridAu, WY=7202383089en_HK
dc.identifier.scopusauthoridChan, ACL=16047349300en_HK
dc.identifier.scopusauthoridCnow, LWC=6504159350en_HK
dc.identifier.scopusauthoridLiang, R=26643224900en_HK

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