File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Prevalence, clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population: a population-based study

TitlePrevalence, clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population: a population-based study
Authors
Issue Date2003
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
Citation
Alimentary Pharmacology and Therapeutics, 2003, v. 18 n. 6, p. 595-604 How to Cite?
AbstractBackground: Population-based data on gastro-oesophageal reflux disease in Chinese are lacking. The prevalence, clinical spectrum and health care-seeking behaviour of subjects with gastro-oesophageal reflux disease were studied. Methods: Ethnic Chinese (3605) were invited to participate in a telephone survey using a validated gastro-oesophageal reflux disease questionnaire and the Hospital Anxiety and Depression Scale. Results: A total of 2209 subjects (58% female; mean age, 40.3 years) completed the interview. The annual, monthly and weekly prevalence rates of gastro-oesophageal reflux disease were 29.8%, 8.9% and 2.5%, respectively. Gastro-oesophageal reflux disease symptoms were associated with non-cardiac chest pain [odds ratio (OR), 2.3; 95% confidence interval (95% CI), 1.7-3.1], dyspepsia (OR, 1.9; 95% CI, 1.4-2.5), globus (OR, 1.8; 95% CI, 1.2-2.7), acid feeling in the stomach (OR, 5.8; 95% CI, 4.5-7.5) and the use of non-steroidal anti-inflammatory drugs (OR, 2.3; 95% CI, 1.5-3.6), but not with dysphagia, bronchitis, asthma, hoarseness and pneumonia. Patients with gastro-oesophageal reflux disease had a significantly higher anxiety and depression score and required more days off work when compared with subjects without. The frequency of heartburn (P = 0.032), female gender (P < 0.001), degree of depression (P = 0.004) and social morbidity (P < 0.001) were independent factors associated with health care-seeking behaviour. Conclusion: The prevalence of gastro-oesophageal reflux disease was lower than that in Western populations, but carried a significant socio-economic burden in the studied Chinese population. The frequency of heart-burn, female gender and psychosocial factors were associated with health care utilization in gastro-oesophageal reflux disease.
Persistent Identifierhttp://hdl.handle.net/10722/77661
ISSN
2015 Impact Factor: 6.32
2015 SCImago Journal Rankings: 2.833
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, WMen_HK
dc.contributor.authorLai, KCen_HK
dc.contributor.authorLam, KFen_HK
dc.contributor.authorHui, WMen_HK
dc.contributor.authorHu, WHCen_HK
dc.contributor.authorLam, CLKen_HK
dc.contributor.authorXia, HHXen_HK
dc.contributor.authorHuang, JQen_HK
dc.contributor.authorChan, CKen_HK
dc.contributor.authorLam, SKen_HK
dc.contributor.authorWong, BCYen_HK
dc.date.accessioned2010-09-06T07:34:20Z-
dc.date.available2010-09-06T07:34:20Z-
dc.date.issued2003en_HK
dc.identifier.citationAlimentary Pharmacology and Therapeutics, 2003, v. 18 n. 6, p. 595-604en_HK
dc.identifier.issn0269-2813en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77661-
dc.description.abstractBackground: Population-based data on gastro-oesophageal reflux disease in Chinese are lacking. The prevalence, clinical spectrum and health care-seeking behaviour of subjects with gastro-oesophageal reflux disease were studied. Methods: Ethnic Chinese (3605) were invited to participate in a telephone survey using a validated gastro-oesophageal reflux disease questionnaire and the Hospital Anxiety and Depression Scale. Results: A total of 2209 subjects (58% female; mean age, 40.3 years) completed the interview. The annual, monthly and weekly prevalence rates of gastro-oesophageal reflux disease were 29.8%, 8.9% and 2.5%, respectively. Gastro-oesophageal reflux disease symptoms were associated with non-cardiac chest pain [odds ratio (OR), 2.3; 95% confidence interval (95% CI), 1.7-3.1], dyspepsia (OR, 1.9; 95% CI, 1.4-2.5), globus (OR, 1.8; 95% CI, 1.2-2.7), acid feeling in the stomach (OR, 5.8; 95% CI, 4.5-7.5) and the use of non-steroidal anti-inflammatory drugs (OR, 2.3; 95% CI, 1.5-3.6), but not with dysphagia, bronchitis, asthma, hoarseness and pneumonia. Patients with gastro-oesophageal reflux disease had a significantly higher anxiety and depression score and required more days off work when compared with subjects without. The frequency of heartburn (P = 0.032), female gender (P < 0.001), degree of depression (P = 0.004) and social morbidity (P < 0.001) were independent factors associated with health care-seeking behaviour. Conclusion: The prevalence of gastro-oesophageal reflux disease was lower than that in Western populations, but carried a significant socio-economic burden in the studied Chinese population. The frequency of heart-burn, female gender and psychosocial factors were associated with health care utilization in gastro-oesophageal reflux disease.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APTen_HK
dc.relation.ispartofAlimentary Pharmacology and Therapeuticsen_HK
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.en_HK
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.-
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAnxiety - epidemiologyen_HK
dc.subject.meshChest Pain - epidemiologyen_HK
dc.subject.meshChi-Square Distributionen_HK
dc.subject.meshChina - epidemiologyen_HK
dc.subject.meshDepression - epidemiologyen_HK
dc.subject.meshDyspnea - epidemiologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGastroesophageal Reflux - epidemiology - therapyen_HK
dc.subject.meshHealth Services - utilizationen_HK
dc.subject.meshHealth Surveysen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInterpersonal Relationsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPatient Acceptance of Health Care - statistics & numerical dataen_HK
dc.subject.meshPrevalenceen_HK
dc.subject.meshSex Factorsen_HK
dc.titlePrevalence, clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population: a population-based studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-2813&volume=18&issue=6&spage=595&epage=604&date=2003&atitle=Prevalence,+Clinical+Spectrum+and+Health+Care+Utilization+of+Gastro-Oesophageal+Reflux+Disease+in+a+Chinese+Population:+a+Population-Based+Studyen_HK
dc.identifier.emailWong, WM: wmwongg@hku.hken_HK
dc.identifier.emailLam, KF: hrntlkf@hkucc.hku.hken_HK
dc.identifier.emailHui, WM: hrmehwm@hkucc.hku.hken_HK
dc.identifier.emailLam, CLK: clklam@hku.hk-
dc.identifier.emailLam, SK: deanmed@hku.hk-
dc.identifier.emailWong, BCY: bcywong@hku.hk-
dc.identifier.authorityLam, KF=rp00718en_HK
dc.identifier.authorityLam, CLK=rp00350en_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1046/j.1365-2036.2003.01737.xen_HK
dc.identifier.pmid12969086-
dc.identifier.scopuseid_2-s2.0-0141427804en_HK
dc.identifier.hkuros80731en_HK
dc.identifier.hkuros81920-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0141427804&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume18en_HK
dc.identifier.issue6en_HK
dc.identifier.spage595en_HK
dc.identifier.epage604en_HK
dc.identifier.isiWOS:000185317900006-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, WM=7403972413en_HK
dc.identifier.scopusauthoridLai, KC=7402135595en_HK
dc.identifier.scopusauthoridLam, KF=8948421200en_HK
dc.identifier.scopusauthoridHui, WM=7103196477en_HK
dc.identifier.scopusauthoridHu, WHC=25932937100en_HK
dc.identifier.scopusauthoridLam, CLK=24755913900en_HK
dc.identifier.scopusauthoridXia, HHX=8757161400en_HK
dc.identifier.scopusauthoridHuang, JQ=7403635051en_HK
dc.identifier.scopusauthoridChan, CK=7404813960en_HK
dc.identifier.scopusauthoridLam, SK=7402279473en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK
dc.customcontrol.immutablesml 130730-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats