File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Aggressive hepatocellular carcinoma complicating pregnancy after autologous bone marrow transplantation for non-Hodgkin's lymphoma

TitleAggressive hepatocellular carcinoma complicating pregnancy after autologous bone marrow transplantation for non-Hodgkin's lymphoma
Authors
Issue Date2002
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmt
Citation
Bone Marrow Transplantation, 2002, v. 29 n. 2, p. 177-179 How to Cite?
AbstractIn the Asia-Pacific region, autologous and allogeneic bone marrow transplantation (BMT) in patients infected with the hepatitis B virus (HBV) may be complicated by fatal hepatic failure due to viral reactivation. Survivors may suffer from accelerated hepatitis and cirrhosis. We report the first case of hepatocellular carcinoma (HCC) after autologous BMT for mediastinal B cell lymphoma. The tumor developed rampantly during a planned pregnancy 5 years after BMT. Less than 40 cases of HCC complicating pregnancy have been reported, and outcome is invariably poor. Immunosuppression and HBV reactivation after autologous BMT, as well as immune tolerance and hormonal changes associated with pregnancy may contribute to the rapid tumor growth. Biochemical and radiological surveillance for HCC should be strengthened in HBV carriers after BMT, especially in patients with the histology of chronic liver disease, or biochemical/virological evidence of increased HBV activity.
Persistent Identifierhttp://hdl.handle.net/10722/77654
ISSN
2015 Impact Factor: 3.636
2015 SCImago Journal Rankings: 1.585
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorAu, WYen_HK
dc.contributor.authorLie, AKWen_HK
dc.contributor.authorLiang, Ren_HK
dc.contributor.authorLiu, CLen_HK
dc.contributor.authorShek, TWen_HK
dc.contributor.authorLau, GKen_HK
dc.date.accessioned2010-09-06T07:34:15Z-
dc.date.available2010-09-06T07:34:15Z-
dc.date.issued2002en_HK
dc.identifier.citationBone Marrow Transplantation, 2002, v. 29 n. 2, p. 177-179en_HK
dc.identifier.issn0268-3369en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77654-
dc.description.abstractIn the Asia-Pacific region, autologous and allogeneic bone marrow transplantation (BMT) in patients infected with the hepatitis B virus (HBV) may be complicated by fatal hepatic failure due to viral reactivation. Survivors may suffer from accelerated hepatitis and cirrhosis. We report the first case of hepatocellular carcinoma (HCC) after autologous BMT for mediastinal B cell lymphoma. The tumor developed rampantly during a planned pregnancy 5 years after BMT. Less than 40 cases of HCC complicating pregnancy have been reported, and outcome is invariably poor. Immunosuppression and HBV reactivation after autologous BMT, as well as immune tolerance and hormonal changes associated with pregnancy may contribute to the rapid tumor growth. Biochemical and radiological surveillance for HCC should be strengthened in HBV carriers after BMT, especially in patients with the histology of chronic liver disease, or biochemical/virological evidence of increased HBV activity.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmten_HK
dc.relation.ispartofBone Marrow Transplantationen_HK
dc.subject.meshAdulten_HK
dc.subject.meshBone Marrow Transplantation - adverse effectsen_HK
dc.subject.meshCarcinoma, Hepatocellular - etiology - virologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHepatitis B virus - growth & developmenten_HK
dc.subject.meshHumansen_HK
dc.subject.meshImmunosuppression - adverse effectsen_HK
dc.subject.meshLiver Neoplasms - etiology - virologyen_HK
dc.subject.meshLymphoma, B-Cell - therapyen_HK
dc.subject.meshMediastinal Neoplasms - therapyen_HK
dc.subject.meshNeoplasms, Second Primary - etiology - virologyen_HK
dc.subject.meshPregnancyen_HK
dc.subject.meshPregnancy Complications, Neoplastic - etiology - virologyen_HK
dc.subject.meshTransplantation, Autologousen_HK
dc.subject.meshVirus Activationen_HK
dc.titleAggressive hepatocellular carcinoma complicating pregnancy after autologous bone marrow transplantation for non-Hodgkin's lymphomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-3369&volume=29&spage=177&epage=179&date=2002&atitle=Aggressive+hepatocellular+carcinoma+complicating+pregnancy+after+autologous+bone+marrow+transplantation+for+non-Hodgkin%27s+lymphoma.en_HK
dc.identifier.emailLiang, R:rliang@hku.hken_HK
dc.identifier.authorityLiang, R=rp00345en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1038/sj.bmt.1703339en_HK
dc.identifier.pmid11850714en_HK
dc.identifier.scopuseid_2-s2.0-0036171552en_HK
dc.identifier.hkuros66523en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036171552&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume29en_HK
dc.identifier.issue2en_HK
dc.identifier.spage177en_HK
dc.identifier.epage179en_HK
dc.identifier.isiWOS:000173711700014-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridAu, WY=7202383089en_HK
dc.identifier.scopusauthoridLie, AKW=24284842400en_HK
dc.identifier.scopusauthoridLiang, R=26643224900en_HK
dc.identifier.scopusauthoridLiu, CL=7409789712en_HK
dc.identifier.scopusauthoridShek, TW=7005479861en_HK
dc.identifier.scopusauthoridLau, GK=7102301257en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats