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Article: Treatment of Helicobacter pylori and prevention of gastric cancer

TitleTreatment of Helicobacter pylori and prevention of gastric cancer
Authors
Issue Date2008
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journal.asp?ref=1443-9611&site=1
Citation
Journal Of Digestive Diseases, 2008, v. 9 n. 1, p. 8-13 How to Cite?
AbstractGastric cancer is the second commonest fatal malignancy in the world with a high incidence in China. Helicobacter pylori infection is an important factor in the pathogenesis of gastric cancer. Epidemiological studies have shown a strong causal relationship between H. pylori infection and gastric cancer. Animal studies also show that eradication of H. pylori infection, especially at the early stage, is effective in preventing H. pylori-related gastric carcinogenesis. H. pylori eradication leads to regression and prevents the progression of gastric precancerous lesions, but only in a minority of cases. H. pylori eradication appears to be the most promising approach in gastric cancer prevention. The current available data in human studies showed that H. pylori eradication can reduce the risk of developing gastric cancer and this strategy is more useful in patients without atrophic gastritis or intestinal metaplasia. A longer follow-up and additional studies are needed for better understanding this issue. © Journal compilation © 2008 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology and Blackwell Publishing Asia Pty Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/77592
ISSN
2015 Impact Factor: 1.887
2015 SCImago Journal Rankings: 0.781
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, TKen_HK
dc.contributor.authorWong, BCYen_HK
dc.date.accessioned2010-09-06T07:33:34Z-
dc.date.available2010-09-06T07:33:34Z-
dc.date.issued2008en_HK
dc.identifier.citationJournal Of Digestive Diseases, 2008, v. 9 n. 1, p. 8-13en_HK
dc.identifier.issn1751-2972en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77592-
dc.description.abstractGastric cancer is the second commonest fatal malignancy in the world with a high incidence in China. Helicobacter pylori infection is an important factor in the pathogenesis of gastric cancer. Epidemiological studies have shown a strong causal relationship between H. pylori infection and gastric cancer. Animal studies also show that eradication of H. pylori infection, especially at the early stage, is effective in preventing H. pylori-related gastric carcinogenesis. H. pylori eradication leads to regression and prevents the progression of gastric precancerous lesions, but only in a minority of cases. H. pylori eradication appears to be the most promising approach in gastric cancer prevention. The current available data in human studies showed that H. pylori eradication can reduce the risk of developing gastric cancer and this strategy is more useful in patients without atrophic gastritis or intestinal metaplasia. A longer follow-up and additional studies are needed for better understanding this issue. © Journal compilation © 2008 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology and Blackwell Publishing Asia Pty Ltd.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journal.asp?ref=1443-9611&site=1en_HK
dc.relation.ispartofJournal of Digestive Diseasesen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshAnti-Bacterial Agents - therapeutic useen_HK
dc.subject.meshHelicobacter Infections - complications - drug therapyen_HK
dc.subject.meshHelicobacter pylori - drug effectsen_HK
dc.subject.meshHumansen_HK
dc.subject.meshRisk Factorsen_HK
dc.subject.meshStomach Neoplasms - microbiology - prevention & controlen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleTreatment of Helicobacter pylori and prevention of gastric canceren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1751-2972&volume=9&issue=1&spage=8&epage=13&date=2008&atitle=Treatment+Of+Helicobacter+Pylori+And+Prevention+Of+Gastric+Cancer.en_HK
dc.identifier.emailWong, BCY:bcywong@hku.hken_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1443-9573.2007.00315.xen_HK
dc.identifier.pmid18251788-
dc.identifier.scopuseid_2-s2.0-38849197537en_HK
dc.identifier.hkuros150075en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38849197537&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume9en_HK
dc.identifier.issue1en_HK
dc.identifier.spage8en_HK
dc.identifier.epage13en_HK
dc.identifier.isiWOS:000256982900002-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridCheung, TK=7103334158en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK
dc.identifier.citeulike4544895-

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