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Article: High-resolution computed tomography of bronchiolitis obliterans syndrome after bone marrow transplantation

TitleHigh-resolution computed tomography of bronchiolitis obliterans syndrome after bone marrow transplantation
Authors
Issue Date1998
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/RES
Citation
Respiration, 1998, v. 65 n. 3, p. 187-191 How to Cite?
AbstractHigh-resolution computed tomography (HRCT) has been described to be useful in assessing bronchiolitis obliterans (BO) syndrome in the transplanted lung. Currently, BO syndrome is diagnosed if lung function deterioration shows persistent or progressive irreversible airflow obstruction, with FEV1 of less than 80% of baseline values, without clinical evidence of infection. The aim of this study is to assess the value of HRCT in evaluating BO syndrome after allogenic bone marrow transplantation (BMT). Fourteen HRCT scans were performed in 6 women and 3 men with moderately severe irreversible airflow obstruction and a clinical diagnosis of BO syndrome after BMT. Two patients had normal HRCT scans. In the remaining 7 patients, 7 of 11 HRCT scans were abnormal, with non-specific findings of bronchial dilatation (1), consolidation (2), hypoattenuated areas (4) and vascular attenuation (4). In comparison with the consistency of positive HRCT findings of BO syndrome in transplanted lungs, HRCT surveillance for BO syndrome in post-BMT patients with clinically established disease is of limited value, unless other pulmonary complications such as opportunistic infections are to be excluded.
Persistent Identifierhttp://hdl.handle.net/10722/77435
ISSN
2015 Impact Factor: 2.651
2015 SCImago Journal Rankings: 1.060
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorOoi, GCen_HK
dc.contributor.authorPeh, WCGen_HK
dc.contributor.authorIp, Men_HK
dc.date.accessioned2010-09-06T07:31:52Z-
dc.date.available2010-09-06T07:31:52Z-
dc.date.issued1998en_HK
dc.identifier.citationRespiration, 1998, v. 65 n. 3, p. 187-191en_HK
dc.identifier.issn0025-7931en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77435-
dc.description.abstractHigh-resolution computed tomography (HRCT) has been described to be useful in assessing bronchiolitis obliterans (BO) syndrome in the transplanted lung. Currently, BO syndrome is diagnosed if lung function deterioration shows persistent or progressive irreversible airflow obstruction, with FEV1 of less than 80% of baseline values, without clinical evidence of infection. The aim of this study is to assess the value of HRCT in evaluating BO syndrome after allogenic bone marrow transplantation (BMT). Fourteen HRCT scans were performed in 6 women and 3 men with moderately severe irreversible airflow obstruction and a clinical diagnosis of BO syndrome after BMT. Two patients had normal HRCT scans. In the remaining 7 patients, 7 of 11 HRCT scans were abnormal, with non-specific findings of bronchial dilatation (1), consolidation (2), hypoattenuated areas (4) and vascular attenuation (4). In comparison with the consistency of positive HRCT findings of BO syndrome in transplanted lungs, HRCT surveillance for BO syndrome in post-BMT patients with clinically established disease is of limited value, unless other pulmonary complications such as opportunistic infections are to be excluded.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/RESen_HK
dc.relation.ispartofRespirationen_HK
dc.rightsRespiration. Copyright © S Karger AG.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshBone Marrow Transplantationen_HK
dc.subject.meshBronchiolitis Obliterans - etiology - physiopathology - radiographyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPostoperative Complications - radiographyen_HK
dc.subject.meshRespiratory Function Testsen_HK
dc.subject.meshTomography, X-Ray Computed - methodsen_HK
dc.titleHigh-resolution computed tomography of bronchiolitis obliterans syndrome after bone marrow transplantationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0025-7931&volume=65&spage=187&epage=191&date=1998&atitle=High-resolution+computed+tomography+of+bronchiolitis+obliterans+syndrome+after+bone+marrow+transplantationen_HK
dc.identifier.emailIp, M:msmip@hku.hken_HK
dc.identifier.authorityIp, M=rp00347en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000029257en_HK
dc.identifier.pmid9670299-
dc.identifier.scopuseid_2-s2.0-0031811842en_HK
dc.identifier.hkuros36068en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031811842&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume65en_HK
dc.identifier.issue3en_HK
dc.identifier.spage187en_HK
dc.identifier.epage191en_HK
dc.identifier.isiWOS:000074785700007-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridOoi, GC=7006176119en_HK
dc.identifier.scopusauthoridPeh, WCG=7101824984en_HK
dc.identifier.scopusauthoridIp, M=7102423259en_HK

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