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Article: Effect of 2-(3-carboxy-1-oxopropyl) amino-2-deoxy-D-glucose on human esophageal cancer cell line

TitleEffect of 2-(3-carboxy-1-oxopropyl) amino-2-deoxy-D-glucose on human esophageal cancer cell line
Authors
Issue Date2004
PublisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
Citation
World Journal Of Gastroenterology, 2004, v. 10 n. 22, p. 3380-3381 How to Cite?
AbstractAim: To determine whether 2-(3-carboxy-1-oxopropy1) amino-2-deoxy-D-glucose (COPADG), a derivative of D-amino-glucose, inhibited the growth of human esophageal cancer cell line Eca-109. Methods: Effects of COPADG on Eca-109 cells cultured in RPMI 1640 medium were examined by a tetrazolium-based colorimetric assay (MTT assay). Results: COPADG inhibited the growth of Eca-109 cells in a dose- and time-dependent manner; the maximum inhibition rate was 83.75%. Conclusion: COPADG can directly inhibit the proliferation of Eca-109 cells, which may serve as the experimental evidence for development of new drugs for esophageal cancer therapy. Copyright © 2004 by The WJG.
Persistent Identifierhttp://hdl.handle.net/10722/77376
ISSN
2015 Impact Factor: 2.787
2015 SCImago Journal Rankings: 1.076
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWu, Jen_HK
dc.contributor.authorLu, Hen_HK
dc.contributor.authorZhou, Yen_HK
dc.contributor.authorQiao, Len_HK
dc.contributor.authorJi, Ren_HK
dc.contributor.authorWang, AQen_HK
dc.contributor.authorLiu, WMen_HK
dc.contributor.authorXue, QJen_HK
dc.date.accessioned2010-09-06T07:31:14Z-
dc.date.available2010-09-06T07:31:14Z-
dc.date.issued2004en_HK
dc.identifier.citationWorld Journal Of Gastroenterology, 2004, v. 10 n. 22, p. 3380-3381en_HK
dc.identifier.issn1007-9327en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77376-
dc.description.abstractAim: To determine whether 2-(3-carboxy-1-oxopropy1) amino-2-deoxy-D-glucose (COPADG), a derivative of D-amino-glucose, inhibited the growth of human esophageal cancer cell line Eca-109. Methods: Effects of COPADG on Eca-109 cells cultured in RPMI 1640 medium were examined by a tetrazolium-based colorimetric assay (MTT assay). Results: COPADG inhibited the growth of Eca-109 cells in a dose- and time-dependent manner; the maximum inhibition rate was 83.75%. Conclusion: COPADG can directly inhibit the proliferation of Eca-109 cells, which may serve as the experimental evidence for development of new drugs for esophageal cancer therapy. Copyright © 2004 by The WJG.en_HK
dc.languageengen_HK
dc.publisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htmen_HK
dc.relation.ispartofWorld Journal of Gastroenterologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleEffect of 2-(3-carboxy-1-oxopropyl) amino-2-deoxy-D-glucose on human esophageal cancer cell lineen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1007-9327&volume=10&spage=3380&epage=1&date=2004&atitle=Effect+of+2-(3-carboxy-1-oxopropyl)+amino-2-deoxy-D-glucose+on+human+esophageal+cancer+cell+lineen_HK
dc.identifier.emailQiao, L: lq8688@hotmail.comen_HK
dc.identifier.authorityQiao, L=rp00513en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3748/wjg.v10.i22.3380-
dc.identifier.pmid15484324en_HK
dc.identifier.pmcidPMC4572319-
dc.identifier.scopuseid_2-s2.0-9744246737en_HK
dc.identifier.hkuros132404en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-9744246737&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume10en_HK
dc.identifier.issue22en_HK
dc.identifier.spage3380en_HK
dc.identifier.epage3381en_HK
dc.identifier.isiWOS:000208318200033-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWu, J=7409254006en_HK
dc.identifier.scopusauthoridLu, H=26642892200en_HK
dc.identifier.scopusauthoridZhou, Y=7405362604en_HK
dc.identifier.scopusauthoridQiao, L=7202151719en_HK
dc.identifier.scopusauthoridJi, R=21733585600en_HK
dc.identifier.scopusauthoridWang, AQ=7404619798en_HK
dc.identifier.scopusauthoridLiu, WM=35548548500en_HK
dc.identifier.scopusauthoridXue, QJ=36071456600en_HK

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