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Article: Systemic lupus erythematosus patients with respiratory symptoms: The value of HRCT

TitleSystemic lupus erythematosus patients with respiratory symptoms: The value of HRCT
Authors
Issue Date1997
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/crad
Citation
Clinical Radiology, 1997, v. 52 n. 10, p. 775-781 How to Cite?
AbstractTen Chinese patients with systemic lupus erythematosus (SLE) and with persistent respiratory symptoms were evaluated with high resolution computed tomography (HRCT), chest radiographs and lung function tests. Fourteen of 15 HRCT scans performed were abnormal. The predominant disease pattern, seen in 60% of patients, was one of chronic interstitial lung disease with honeycombing, architectural distortion, parenchymal bands, pleural irregularity, and a lower zone predominance. Three of 10 patients had histological evidence of either lung fibrosis or interstitial pneumonitis. Airways disease and pleural thickening were seen in 20% and 87% of scans, respectively. Pleural thickening and honeycombing were present in 53% and 20% of chest radiographs, respectively. All concurrent lung function tests were abnormal. Reduced diffusion capacity of carbon monoxide (DLCO/VA) was observed in 60% of lung function tests. There was no correlation between duration of disease and DLCO/VA. However, pathological reduction of DLCO/VA was seen in 71% of patients with honeycombing, and 88% of patients with ground glass opacity. Our study has documented a high incidence of HRCT features of chronic lung destruction and a lower zone predominance in SLE patients with persistent respiratory symptoms.
Persistent Identifierhttp://hdl.handle.net/10722/77206
ISSN
2015 Impact Factor: 2.151
2015 SCImago Journal Rankings: 0.864
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorOoi, GCen_HK
dc.contributor.authorNgan, Hen_HK
dc.contributor.authorPeh, WCGen_HK
dc.contributor.authorMok, MYen_HK
dc.contributor.authorIp, Men_HK
dc.date.accessioned2010-09-06T07:29:24Z-
dc.date.available2010-09-06T07:29:24Z-
dc.date.issued1997en_HK
dc.identifier.citationClinical Radiology, 1997, v. 52 n. 10, p. 775-781en_HK
dc.identifier.issn0009-9260en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77206-
dc.description.abstractTen Chinese patients with systemic lupus erythematosus (SLE) and with persistent respiratory symptoms were evaluated with high resolution computed tomography (HRCT), chest radiographs and lung function tests. Fourteen of 15 HRCT scans performed were abnormal. The predominant disease pattern, seen in 60% of patients, was one of chronic interstitial lung disease with honeycombing, architectural distortion, parenchymal bands, pleural irregularity, and a lower zone predominance. Three of 10 patients had histological evidence of either lung fibrosis or interstitial pneumonitis. Airways disease and pleural thickening were seen in 20% and 87% of scans, respectively. Pleural thickening and honeycombing were present in 53% and 20% of chest radiographs, respectively. All concurrent lung function tests were abnormal. Reduced diffusion capacity of carbon monoxide (DLCO/VA) was observed in 60% of lung function tests. There was no correlation between duration of disease and DLCO/VA. However, pathological reduction of DLCO/VA was seen in 71% of patients with honeycombing, and 88% of patients with ground glass opacity. Our study has documented a high incidence of HRCT features of chronic lung destruction and a lower zone predominance in SLE patients with persistent respiratory symptoms.en_HK
dc.languageengen_HK
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/craden_HK
dc.relation.ispartofClinical Radiologyen_HK
dc.subject.meshAdulten_HK
dc.subject.meshChronic Diseaseen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLung Diseases, Interstitial - etiology - radiographyen_HK
dc.subject.meshLupus Erythematosus, Systemic - complicationsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPleural Diseases - etiology - radiographyen_HK
dc.subject.meshRespiration Disorders - etiology - physiopathology - radiographyen_HK
dc.subject.meshRespiratory Function Testsen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.titleSystemic lupus erythematosus patients with respiratory symptoms: The value of HRCTen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0009-9260&volume=52&spage=775&epage=781&date=1998&atitle=Systemic+lupus+erythematosus+patients+with+respiratory+symptoms:+the+value+of+H.R.C.Ten_HK
dc.identifier.emailMok, MY:temy@hkucc.hku.hken_HK
dc.identifier.emailIp, M:msmip@hku.hken_HK
dc.identifier.authorityMok, MY=rp00490en_HK
dc.identifier.authorityIp, M=rp00347en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0009-9260(97)80159-6en_HK
dc.identifier.pmid9366539-
dc.identifier.scopuseid_2-s2.0-0030853231en_HK
dc.identifier.hkuros34218en_HK
dc.identifier.volume52en_HK
dc.identifier.issue10en_HK
dc.identifier.spage775en_HK
dc.identifier.epage781en_HK
dc.identifier.isiWOS:A1997YB77700010-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridOoi, GC=7006176119en_HK
dc.identifier.scopusauthoridNgan, H=7102173824en_HK
dc.identifier.scopusauthoridPeh, WCG=7101824984en_HK
dc.identifier.scopusauthoridMok, MY=7006024184en_HK
dc.identifier.scopusauthoridIp, M=7102423259en_HK

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