File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: Serial analysis of JAK2 mutation in a patient who developed essential thrombocythemia after orthotopic liver transplantation
  • Basic View
  • Metadata View
  • XML View
TitleSerial analysis of JAK2 mutation in a patient who developed essential thrombocythemia after orthotopic liver transplantation
 
AuthorsAu, WY1 2
Fung, A1
Liu, CL1
Fan, ST1
Ma, SK1
Liang, R1
Kwong, YL1
 
KeywordsEssential thrombocythemia
JAK2
Liver transplantation
 
Issue Date2006
 
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105
 
CitationAmerican Journal Of Hematology, 2006, v. 81 n. 11, p. 880-882 [How to Cite?]
DOI: http://dx.doi.org/10.1002/ajh.20638
 
AbstractA 52-year-old man developed essential thrombocythemia (ET) with JAK2 V617F mutation after orthotopic liver transplantation (OLT). Retrospective analysis showed that, despite a low platelet count, the JAK2 mutation was already found at presentation 14 months before OLT. The high platelet count that would have been typical of ET might be masked by the cirrhosis-related hypersplenism. Thrombocythemia became obvious after OLT. The patient subsequently developed blastic transformation 12 months afterward, a process probably accelerated by the immunosuppression required for the OLT. © 2006 Wiley-Liss, Inc.
 
ISSN0361-8609
2013 Impact Factor: 3.477
 
DOIhttp://dx.doi.org/10.1002/ajh.20638
 
ISI Accession Number IDWOS:000241906700012
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorAu, WY
 
dc.contributor.authorFung, A
 
dc.contributor.authorLiu, CL
 
dc.contributor.authorFan, ST
 
dc.contributor.authorMa, SK
 
dc.contributor.authorLiang, R
 
dc.contributor.authorKwong, YL
 
dc.date.accessioned2010-09-06T07:27:27Z
 
dc.date.available2010-09-06T07:27:27Z
 
dc.date.issued2006
 
dc.description.abstractA 52-year-old man developed essential thrombocythemia (ET) with JAK2 V617F mutation after orthotopic liver transplantation (OLT). Retrospective analysis showed that, despite a low platelet count, the JAK2 mutation was already found at presentation 14 months before OLT. The high platelet count that would have been typical of ET might be masked by the cirrhosis-related hypersplenism. Thrombocythemia became obvious after OLT. The patient subsequently developed blastic transformation 12 months afterward, a process probably accelerated by the immunosuppression required for the OLT. © 2006 Wiley-Liss, Inc.
 
dc.description.naturelink_to_OA_fulltext
 
dc.identifier.citationAmerican Journal Of Hematology, 2006, v. 81 n. 11, p. 880-882 [How to Cite?]
DOI: http://dx.doi.org/10.1002/ajh.20638
 
dc.identifier.doihttp://dx.doi.org/10.1002/ajh.20638
 
dc.identifier.epage882
 
dc.identifier.hkuros136803
 
dc.identifier.hkuros124840
 
dc.identifier.isiWOS:000241906700012
 
dc.identifier.issn0361-8609
2013 Impact Factor: 3.477
 
dc.identifier.issue11
 
dc.identifier.openurl
 
dc.identifier.pmid16929538
 
dc.identifier.scopuseid_2-s2.0-33749439176
 
dc.identifier.spage880
 
dc.identifier.urihttp://hdl.handle.net/10722/77024
 
dc.identifier.volume81
 
dc.languageeng
 
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105
 
dc.publisher.placeUnited States
 
dc.relation.ispartofAmerican Journal of Hematology
 
dc.relation.referencesReferences in Scopus
 
dc.rightsAmerican Journal of Hematology. Copyright © John Wiley & Sons, Inc.
 
dc.subject.meshAmino Acid Substitution
 
dc.subject.meshAutopsy
 
dc.subject.meshFatal Outcome
 
dc.subject.meshHepatitis B - surgery
 
dc.subject.meshHumans
 
dc.subject.meshJanus Kinase 2 - genetics
 
dc.subject.meshLiver Transplantation - adverse effects
 
dc.subject.meshMale
 
dc.subject.meshMiddle Aged
 
dc.subject.meshPostoperative Complications
 
dc.subject.meshThrombocytosis - genetics
 
dc.subjectEssential thrombocythemia
 
dc.subjectJAK2
 
dc.subjectLiver transplantation
 
dc.titleSerial analysis of JAK2 mutation in a patient who developed essential thrombocythemia after orthotopic liver transplantation
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Au, WY</contributor.author>
<contributor.author>Fung, A</contributor.author>
<contributor.author>Liu, CL</contributor.author>
<contributor.author>Fan, ST</contributor.author>
<contributor.author>Ma, SK</contributor.author>
<contributor.author>Liang, R</contributor.author>
<contributor.author>Kwong, YL</contributor.author>
<date.accessioned>2010-09-06T07:27:27Z</date.accessioned>
<date.available>2010-09-06T07:27:27Z</date.available>
<date.issued>2006</date.issued>
<identifier.citation>American Journal Of Hematology, 2006, v. 81 n. 11, p. 880-882</identifier.citation>
<identifier.issn>0361-8609</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/77024</identifier.uri>
<description.abstract>A 52-year-old man developed essential thrombocythemia (ET) with JAK2 V617F mutation after orthotopic liver transplantation (OLT). Retrospective analysis showed that, despite a low platelet count, the JAK2 mutation was already found at presentation 14 months before OLT. The high platelet count that would have been typical of ET might be masked by the cirrhosis-related hypersplenism. Thrombocythemia became obvious after OLT. The patient subsequently developed blastic transformation 12 months afterward, a process probably accelerated by the immunosuppression required for the OLT. &#169; 2006 Wiley-Liss, Inc.</description.abstract>
<language>eng</language>
<publisher>John Wiley &amp; Sons, Inc. The Journal&apos;s web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105</publisher>
<relation.ispartof>American Journal of Hematology</relation.ispartof>
<rights>American Journal of Hematology. Copyright &#169; John Wiley &amp; Sons, Inc.</rights>
<subject>Essential thrombocythemia</subject>
<subject>JAK2</subject>
<subject>Liver transplantation</subject>
<subject.mesh>Amino Acid Substitution</subject.mesh>
<subject.mesh>Autopsy</subject.mesh>
<subject.mesh>Fatal Outcome</subject.mesh>
<subject.mesh>Hepatitis B - surgery</subject.mesh>
<subject.mesh>Humans</subject.mesh>
<subject.mesh>Janus Kinase 2 - genetics</subject.mesh>
<subject.mesh>Liver Transplantation - adverse effects</subject.mesh>
<subject.mesh>Male</subject.mesh>
<subject.mesh>Middle Aged</subject.mesh>
<subject.mesh>Postoperative Complications</subject.mesh>
<subject.mesh>Thrombocytosis - genetics</subject.mesh>
<title>Serial analysis of JAK2 mutation in a patient who developed essential thrombocythemia after orthotopic liver transplantation</title>
<type>Article</type>
<identifier.openurl>http://library.hku.hk:4550/resserv?sid=HKU:IR&amp;issn=0361-8609&amp;volume=81&amp;issue=1&amp;spage=880&amp;epage=882&amp;date=2006&amp;atitle=Serial+analysis+of+JAK2+mutation+in+a+patient+who+developed+essential+thrombocythemia+after+orthotopic+liver+transplantation</identifier.openurl>
<description.nature>link_to_OA_fulltext</description.nature>
<identifier.doi>10.1002/ajh.20638</identifier.doi>
<identifier.pmid>16929538</identifier.pmid>
<identifier.scopus>eid_2-s2.0-33749439176</identifier.scopus>
<identifier.hkuros>136803</identifier.hkuros>
<identifier.hkuros>124840</identifier.hkuros>
<relation.references>http://www.scopus.com/mlt/select.url?eid=2-s2.0-33749439176&amp;selection=ref&amp;src=s&amp;origin=recordpage</relation.references>
<identifier.volume>81</identifier.volume>
<identifier.issue>11</identifier.issue>
<identifier.spage>880</identifier.spage>
<identifier.epage>882</identifier.epage>
<identifier.isi>WOS:000241906700012</identifier.isi>
<publisher.place>United States</publisher.place>
<bitstream.url>http://hub.hku.hk/bitstream/10722/77024/1/re01.htm</bitstream.url>
</item>
Author Affiliations
  1. The University of Hong Kong
  2. Queen Mary Hospital Hong Kong