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Article: Castleman's disease and mesangial proliferative glomerulonephritis: The role of interleukin-6

TitleCastleman's disease and mesangial proliferative glomerulonephritis: The role of interleukin-6
Authors
Issue Date1998
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/NEF
Citation
Nephron, 1998, v. 78 n. 3, p. 323-327 How to Cite?
AbstractRenal complications of Castleman's disease (angiofollicular lymph node hyperplasia) are uncommon. The reported cases are very heterogeneous and their renal pathology ranged from minimal change disease, mesangial proliferative glomerulonephritis, to amyloidosis. We have previously reported two cases of Castleman's disease with renal complications. We now present two more such cases. In contrast to other reports, all our cases are of the plasma cell type and their renal pathology showed remarkable similarities, namely mesangial proliferation, interstitial plasma cell infiltration and negative immunofluorescence. The level of serum interleukin-6 (IL-6) in both patients was elevated at presentation and came down with immunosuppressive therapy.
Persistent Identifierhttp://hdl.handle.net/10722/76986
ISSN
2004 Impact Factor: 1.462
2006 SCImago Journal Rankings: 0.715
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, KWen_HK
dc.date.accessioned2010-09-06T07:27:02Z-
dc.date.available2010-09-06T07:27:02Z-
dc.date.issued1998en_HK
dc.identifier.citationNephron, 1998, v. 78 n. 3, p. 323-327en_HK
dc.identifier.issn0028-2766en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76986-
dc.description.abstractRenal complications of Castleman's disease (angiofollicular lymph node hyperplasia) are uncommon. The reported cases are very heterogeneous and their renal pathology ranged from minimal change disease, mesangial proliferative glomerulonephritis, to amyloidosis. We have previously reported two cases of Castleman's disease with renal complications. We now present two more such cases. In contrast to other reports, all our cases are of the plasma cell type and their renal pathology showed remarkable similarities, namely mesangial proliferation, interstitial plasma cell infiltration and negative immunofluorescence. The level of serum interleukin-6 (IL-6) in both patients was elevated at presentation and came down with immunosuppressive therapy.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/NEFen_HK
dc.relation.ispartofNephronen_HK
dc.rightsNephron. Copyright © S Karger AG.en_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGiant Lymph Node Hyperplasia - blood - complicationsen_HK
dc.subject.meshGlomerulonephritis, Membranoproliferative - blood - etiologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInterleukin-6 - blooden_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.titleCastleman's disease and mesangial proliferative glomerulonephritis: The role of interleukin-6en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0028-2766&volume=78&spage=323&epage=327&date=1999&atitle=Castleman%27s+disease+and+mesangial+proliferative+glomerulonephritis:+the+role+of+interleukin-6en_HK
dc.identifier.emailChan, KW:hrmtckw@hku.hken_HK
dc.identifier.authorityChan, KW=rp00330en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000044943en_HK
dc.identifier.pmid9546694-
dc.identifier.scopuseid_2-s2.0-0031888174en_HK
dc.identifier.hkuros31524en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031888174&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume78en_HK
dc.identifier.issue3en_HK
dc.identifier.spage323en_HK
dc.identifier.epage327en_HK
dc.identifier.isiWOS:000072398500014-
dc.publisher.placeSwitzerlanden_HK

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