File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: Age-related osteoporosis in Chinese: an evaluation of the response of intestinal calcium absorption and calcitrophic hormones to dietary calcium deprivation

TitleAge-related osteoporosis in Chinese: an evaluation of the response of intestinal calcium absorption and calcitrophic hormones to dietary calcium deprivation
Authors
Issue Date1998
PublisherSpringer UK. The Journal's web site is located at http://www.springer.com/medicine/orthopedics/journal/198
Citation
The 1998 European Congress on Osteoporosis, Berlin, Germany, 11-15 September 1998. In Osteoporosis International, 1998, v. 8 n. 3 suppl., p. 40, abstract no. P093 How to Cite?
AbstractLow dietary calcium is a recognised risk for osteoporotic fractures. We evaluated the pathogenesis of age-related osteoporosis in a group of Chinese women with a mean calcium intake of 561±183 mg/day. When compared to young healthy controls, the osteoporotic subjects had negative calcium balance, raised urinary calcium excretion (0.63±O.47 vs 0.27±O.16 mol/mol, p
Persistent Identifierhttp://hdl.handle.net/10722/76899
ISSN
2015 Impact Factor: 3.445
2015 SCImago Journal Rankings: 1.460

 

DC FieldValueLanguage
dc.contributor.authorKung, AWC-
dc.contributor.authorLuk, KDK-
dc.contributor.authorChu, LW-
dc.contributor.authorChiu, PKY-
dc.date.accessioned2010-09-06T07:26:07Z-
dc.date.available2010-09-06T07:26:07Z-
dc.date.issued1998-
dc.identifier.citationThe 1998 European Congress on Osteoporosis, Berlin, Germany, 11-15 September 1998. In Osteoporosis International, 1998, v. 8 n. 3 suppl., p. 40, abstract no. P093-
dc.identifier.issn0937-941X-
dc.identifier.urihttp://hdl.handle.net/10722/76899-
dc.description.abstractLow dietary calcium is a recognised risk for osteoporotic fractures. We evaluated the pathogenesis of age-related osteoporosis in a group of Chinese women with a mean calcium intake of 561±183 mg/day. When compared to young healthy controls, the osteoporotic subjects had negative calcium balance, raised urinary calcium excretion (0.63±O.47 vs 0.27±O.16 mol/mol, p<O.05) , low calc it rio I level (74±26 vs 108±33 pmol/l, p<0.02) and secondary hyperparathyroidism (3.67±1.54 vs 2.67±1.62 pmol/l, p<O.05). The fractional 45Ca absorption was around 61 % during unmodified diet in both osteoporotic subjects and in young controls which increased to 71 % and 68% respectively during low calcium diet. When subjected to graded dietary calcium deprivation, calcitriollevels failed to increase and urinary calcium excretion perSisted in the osteoporotic subjects. Supplementation of 1200mg calcium in the osteoporotic subjects was able to lower PTH level (2.27±1.09, vs 2.84±1.19 pmol/l, vs unmodified diet, p<0.005) but further suppressed serum calcitriollevel (60±21 vs 79±19 pmol/l, p<0.01) and decreased fractional 45Ca absorption (49±11% vs 61±18%, p<0.01), suggesting thatthis level of calcium intake was excessive and offset the potent compensatory ability of the intestine to absorb calcium. Based on the response of the calcitrophic hormones and fractional 45Ca absorption, a daily intake of 1000 - 1200mg calcium is probably adequate for the Chinese population.-
dc.languageeng-
dc.publisherSpringer UK. The Journal's web site is located at http://www.springer.com/medicine/orthopedics/journal/198-
dc.relation.ispartofOsteoporosis International: with other metabolic bone diseases-
dc.rightsThe original publication is available at www.springerlink.com-
dc.titleAge-related osteoporosis in Chinese: an evaluation of the response of intestinal calcium absorption and calcitrophic hormones to dietary calcium deprivation-
dc.typeConference_Paper-
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0937-941X&volume=Suppl 3&spage=P093&epage=&date=1998&atitle=Age-related+osteoporosis+in+Chinese:+an+evaluation+of+the+response+of+intestinal+calcium+absorption+and+calcitrophic+hormones+to+dietary+calcium+deprivation.en_HK
dc.identifier.emailKung, AWC: awckung@hku.hk-
dc.identifier.emailLuk, KDK: cm21000@hku.hk-
dc.identifier.emailChu, LW: lwchu@hku.hk-
dc.identifier.emailChiu, PKY: pkychiu@hkucc.hku.hk-
dc.identifier.authorityKung, AWC=rp00368-
dc.identifier.authorityLuk, KDK=rp00333-
dc.identifier.authorityChiu, PKY=rp00379-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1007/BF03262413-
dc.identifier.hkuros41427-
dc.identifier.volume8-
dc.identifier.issue3 suppl.-
dc.identifier.spage40, abstract no. P093-
dc.identifier.epage40, abstract no. P093-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats