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Article: Squamous cell carcinoma of the tongue complicating chronic oral mucosal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

TitleSquamous cell carcinoma of the tongue complicating chronic oral mucosal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Authors
Issue Date2004
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105
Citation
American Journal Of Hematology, 2004, v. 77 n. 2, p. 200-202 How to Cite?
AbstractTwo patients underwent allogeneic hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia. Chronic graft-versus-host disease (GVHD) developed, with persistent symptomatic oral lesions. At 2 and 6 years post-HSCT, both patients developed squamous cell carcinoma (SCC) of the tongue in areas previously involved by chronic GVHD. None had any known risk factor for SCC. Histologically, moderate to severe dysplasia was present in noncancerous oral mucosa. Oral SCC is rarely described after HSCT, and a review of the reported cases showed chronic GVHD to be a common risk, suggesting that the chronic inflammation associated with GVHD might be of pathogenetic significance. © 2004 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/76734
ISSN
2015 Impact Factor: 5.0
2015 SCImago Journal Rankings: 1.761
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSzeto, CHen_HK
dc.contributor.authorShek, TWHen_HK
dc.contributor.authorLie, AKWen_HK
dc.contributor.authorAu, WYen_HK
dc.contributor.authorYuen, APWen_HK
dc.contributor.authorKwong, YLen_HK
dc.date.accessioned2010-09-06T07:24:22Z-
dc.date.available2010-09-06T07:24:22Z-
dc.date.issued2004en_HK
dc.identifier.citationAmerican Journal Of Hematology, 2004, v. 77 n. 2, p. 200-202en_HK
dc.identifier.issn0361-8609en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76734-
dc.description.abstractTwo patients underwent allogeneic hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia. Chronic graft-versus-host disease (GVHD) developed, with persistent symptomatic oral lesions. At 2 and 6 years post-HSCT, both patients developed squamous cell carcinoma (SCC) of the tongue in areas previously involved by chronic GVHD. None had any known risk factor for SCC. Histologically, moderate to severe dysplasia was present in noncancerous oral mucosa. Oral SCC is rarely described after HSCT, and a review of the reported cases showed chronic GVHD to be a common risk, suggesting that the chronic inflammation associated with GVHD might be of pathogenetic significance. © 2004 Wiley-Liss, Inc.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105en_HK
dc.relation.ispartofAmerican Journal of Hematologyen_HK
dc.rightsAmerican Journal of Hematology. Copyright © John Wiley & Sons, Inc.en_HK
dc.subject.meshAcute Diseaseen_HK
dc.subject.meshCarcinoma, Squamous Cell - etiology - surgeryen_HK
dc.subject.meshGraft vs Host Disease - complicationsen_HK
dc.subject.meshHematopoietic Stem Cell Transplantationen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLeukemia, Myeloid - surgeryen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNeoplasms, Second Primary - etiology - surgeryen_HK
dc.subject.meshTongue Neoplasms - etiology - surgeryen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleSquamous cell carcinoma of the tongue complicating chronic oral mucosal graft-versus-host disease after allogeneic hematopoietic stem cell transplantationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0361-8609&volume=77&issue=2&spage=200&epage=202&date=2004&atitle=Squamous+cell+carcinoma+of+the+tongue+complicating+chronic+oral+mucosal+graft-versus-host+disease+after+allogeneic+hematopoietic+stem+cell+transplantationen_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/ajh.20160en_HK
dc.identifier.pmid15389910-
dc.identifier.scopuseid_2-s2.0-4644225381en_HK
dc.identifier.hkuros94718en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-4644225381&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume77en_HK
dc.identifier.issue2en_HK
dc.identifier.spage200en_HK
dc.identifier.epage202en_HK
dc.identifier.isiWOS:000224108400019-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSzeto, CH=7006622134en_HK
dc.identifier.scopusauthoridShek, TWH=7005479861en_HK
dc.identifier.scopusauthoridLie, AKW=7004510870en_HK
dc.identifier.scopusauthoridAu, WY=7202383089en_HK
dc.identifier.scopusauthoridYuen, APW=7006290111en_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK

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