File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: Blood pressure response to transition from supine to standing posture using an orthostatic response algorithm

TitleBlood pressure response to transition from supine to standing posture using an orthostatic response algorithm
Authors
Issue Date2005
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1
Citation
Cardiostim 2004 Meeting, Nice, France, 16-19 June 2004. In Pace - Pacing And Clinical Electrophysiology, 2005, v. 28 suppl. 1, p. S242-S245 How to Cite?
AbstractUpon standing from a supine position, the normal response is an increase in heart rate to maintain blood pressure (BP). In patients with chronotropic incompetence, heart rate may not increase upon standing, and they may experience orthostatic hypotension (OH). We evaluated a new orthostatic response (OSR) pacing algorithm that uses an accelerometer signal to detect sudden activity following prolonged rest to trigger a 2 minutes increase in pacing rate to 94 bpm. Ten recipients of DDDR pacemakers which contain the OSR compensation algorithm (mean age = 77 ± 9 years, 8 women) with sick sinus syndrome (n = 6) or atrioventricular block (n = 4) were studied. In all patients BP was measured before and 0.5, 1, 1.5, 2, and 3 minutes after standing at their programmed base rate. A 20 mmHg fall in systolic BP upon standing was observed in five patients (OH patients), while the other five were considered non-OH patients. The measurements were repeated with the OSR algorithm turned on. Mean BP was defined as 1/3 systolic BP + 2/3 diastolic BP. Baseline heart rate was significantly slower in OH patients (62 ± 2 bpm) than non-OH patients (71 ± 7 bpm, P < 0.05). In OH patients mean BP increased significantly upon standing (P < 0.05 for all comparisons) with the algorithm ON instead of decreasing with the algorithm OFF, at 1 minute (+3.4 vs -10.3 mmHg), 1.5 minutes (+7.0 vs -4.9 mmHg), 2 minutes (+1.6 vs -6.7 mmHg), and 3 minutes (+2.5 vs -8.5 mmHg). These preliminary results suggest that the OSR algorithm maintains BP upon standing in patients with OH.
Persistent Identifierhttp://hdl.handle.net/10722/76502
ISSN
2015 Impact Factor: 1.156
2015 SCImago Journal Rankings: 0.662
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTse, HFen_HK
dc.contributor.authorSiu, CWen_HK
dc.contributor.authorTsang, Ven_HK
dc.contributor.authorYu, Cen_HK
dc.contributor.authorPark, Een_HK
dc.contributor.authorBornzin, GAen_HK
dc.contributor.authorBenser, MEen_HK
dc.contributor.authorLau, CPen_HK
dc.date.accessioned2010-09-06T07:21:55Z-
dc.date.available2010-09-06T07:21:55Z-
dc.date.issued2005en_HK
dc.identifier.citationCardiostim 2004 Meeting, Nice, France, 16-19 June 2004. In Pace - Pacing And Clinical Electrophysiology, 2005, v. 28 suppl. 1, p. S242-S245en_HK
dc.identifier.issn0147-8389en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76502-
dc.description.abstractUpon standing from a supine position, the normal response is an increase in heart rate to maintain blood pressure (BP). In patients with chronotropic incompetence, heart rate may not increase upon standing, and they may experience orthostatic hypotension (OH). We evaluated a new orthostatic response (OSR) pacing algorithm that uses an accelerometer signal to detect sudden activity following prolonged rest to trigger a 2 minutes increase in pacing rate to 94 bpm. Ten recipients of DDDR pacemakers which contain the OSR compensation algorithm (mean age = 77 ± 9 years, 8 women) with sick sinus syndrome (n = 6) or atrioventricular block (n = 4) were studied. In all patients BP was measured before and 0.5, 1, 1.5, 2, and 3 minutes after standing at their programmed base rate. A 20 mmHg fall in systolic BP upon standing was observed in five patients (OH patients), while the other five were considered non-OH patients. The measurements were repeated with the OSR algorithm turned on. Mean BP was defined as 1/3 systolic BP + 2/3 diastolic BP. Baseline heart rate was significantly slower in OH patients (62 ± 2 bpm) than non-OH patients (71 ± 7 bpm, P < 0.05). In OH patients mean BP increased significantly upon standing (P < 0.05 for all comparisons) with the algorithm ON instead of decreasing with the algorithm OFF, at 1 minute (+3.4 vs -10.3 mmHg), 1.5 minutes (+7.0 vs -4.9 mmHg), 2 minutes (+1.6 vs -6.7 mmHg), and 3 minutes (+2.5 vs -8.5 mmHg). These preliminary results suggest that the OSR algorithm maintains BP upon standing in patients with OH.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1en_HK
dc.relation.ispartofPACE - Pacing and Clinical Electrophysiologyen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAlgorithmsen_HK
dc.subject.meshBlood Pressure - physiologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshHypotension, Orthostatic - physiopathologyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshPacemaker, Artificialen_HK
dc.subject.meshPosture - physiologyen_HK
dc.subject.meshSupine Positionen_HK
dc.titleBlood pressure response to transition from supine to standing posture using an orthostatic response algorithmen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0147-8389&volume=28 Suppl 1&spage=S242&epage=5&date=2005&atitle=Blood+pressure+response+to+transition+from+supine+to+standing+posture+using+an+orthostatic+response+algorithm.en_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.emailSiu, CW:cwdsiu@hkucc.hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.identifier.authoritySiu, CW=rp00534en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1540-8159.2005.00054.xen_HK
dc.identifier.pmid15683506-
dc.identifier.scopuseid_2-s2.0-12844258215en_HK
dc.identifier.hkuros99331en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-12844258215&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume28en_HK
dc.identifier.issuesuppl. 1en_HK
dc.identifier.spageS242en_HK
dc.identifier.epageS245en_HK
dc.identifier.isiWOS:000227338100057-
dc.publisher.placeUnited Statesen_HK
dc.description.otherCardiostim 2004 Meeting, Nice, France, 16-19 June 2004. In Pace - Pacing And Clinical Electrophysiology, 2005, v. 28 suppl. 1, p. S242-S245-
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.scopusauthoridSiu, CW=7006550690en_HK
dc.identifier.scopusauthoridTsang, V=7005694255en_HK
dc.identifier.scopusauthoridYu, C=7404978038en_HK
dc.identifier.scopusauthoridPark, E=7402224798en_HK
dc.identifier.scopusauthoridBornzin, GA=6602728974en_HK
dc.identifier.scopusauthoridBenser, ME=6602158430en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats