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Article: Coexistence between colorectal cancer/adenoma and coronary artery disease: Results from 1382 patients

TitleCoexistence between colorectal cancer/adenoma and coronary artery disease: Results from 1382 patients
Authors
Issue Date2006
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
Citation
Alimentary Pharmacology And Therapeutics, 2006, v. 24 n. 3, p. 535-539 How to Cite?
AbstractBackground: Common risk factors exist in colorectal neoplasia (cancer or adenoma) and coronary artery disease. Aim: To investigate in a retrospective study if there is coexistence of the two events in patients ≥50 years. Methods: Computer data on colonoscopies performed on symptomatic patients, the corresponding medical record and colonic histology in 1997-2000 were retrieved. History of coronary artery disease was recorded. To adjust for the factors of age and sex, bivariate logistic regression analysis was used to test for coexistence. Results: 1382 patients were recruited. Colorectal neoplasia and history of coronary artery disease were present in 27% (373) and 12% (167) of patients, respectively. The mean age of patients was older in colorectal neoplasia+ (75 ± 11 vs. 69 ± 13 years, P < 0.0001) and in coronary artery disease+ (79 ± 9 vs. 69 ± 12 years, P < 0.0001) patients. Male was the predominant sex in colorectal neoplasia+: 33% vs. 22% (P < 0.0001), but not in coronary artery disease+ (P = 0.29). Colorectal neoplasia+ patients were more likely to have coronary artery disease+ [21.2% (79/ 373) vs. 8.8% (89/1098) (P < 0.0001)]. Bivariate logistic regression analysis showed strong association between the two events (OR: 2.12, 95% CI: 1.5, 3.0). Conclusion: There is strong coexistence of colorectal neoplasia and coronary artery disease, probably due to exposure to common risk factors. © 2006 The Authors.
Persistent Identifierhttp://hdl.handle.net/10722/76411
ISSN
2015 Impact Factor: 6.32
2015 SCImago Journal Rankings: 2.833
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, AOOen_HK
dc.contributor.authorLam, KFen_HK
dc.contributor.authorTong, Ten_HK
dc.contributor.authorSiu, DCWen_HK
dc.contributor.authorJim, MHen_HK
dc.contributor.authorHui, WMen_HK
dc.contributor.authorLai, KCen_HK
dc.contributor.authorYuen, MFen_HK
dc.contributor.authorLam, SKen_HK
dc.contributor.authorWong, BCYen_HK
dc.date.accessioned2010-09-06T07:20:57Z-
dc.date.available2010-09-06T07:20:57Z-
dc.date.issued2006en_HK
dc.identifier.citationAlimentary Pharmacology And Therapeutics, 2006, v. 24 n. 3, p. 535-539en_HK
dc.identifier.issn0269-2813en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76411-
dc.description.abstractBackground: Common risk factors exist in colorectal neoplasia (cancer or adenoma) and coronary artery disease. Aim: To investigate in a retrospective study if there is coexistence of the two events in patients ≥50 years. Methods: Computer data on colonoscopies performed on symptomatic patients, the corresponding medical record and colonic histology in 1997-2000 were retrieved. History of coronary artery disease was recorded. To adjust for the factors of age and sex, bivariate logistic regression analysis was used to test for coexistence. Results: 1382 patients were recruited. Colorectal neoplasia and history of coronary artery disease were present in 27% (373) and 12% (167) of patients, respectively. The mean age of patients was older in colorectal neoplasia+ (75 ± 11 vs. 69 ± 13 years, P < 0.0001) and in coronary artery disease+ (79 ± 9 vs. 69 ± 12 years, P < 0.0001) patients. Male was the predominant sex in colorectal neoplasia+: 33% vs. 22% (P < 0.0001), but not in coronary artery disease+ (P = 0.29). Colorectal neoplasia+ patients were more likely to have coronary artery disease+ [21.2% (79/ 373) vs. 8.8% (89/1098) (P < 0.0001)]. Bivariate logistic regression analysis showed strong association between the two events (OR: 2.12, 95% CI: 1.5, 3.0). Conclusion: There is strong coexistence of colorectal neoplasia and coronary artery disease, probably due to exposure to common risk factors. © 2006 The Authors.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APTen_HK
dc.relation.ispartofAlimentary Pharmacology and Therapeuticsen_HK
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.en_HK
dc.subject.meshAdenoma - complicationsen_HK
dc.subject.meshAgeden_HK
dc.subject.meshColorectal Neoplasms - complicationsen_HK
dc.subject.meshCoronary Artery Disease - complicationsen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshRisk Factorsen_HK
dc.titleCoexistence between colorectal cancer/adenoma and coronary artery disease: Results from 1382 patientsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-2813&volume=24&issue=3&spage=535&epage=9&date=2006&atitle=Coexistence+between+colorectal+cancer/adenoma+and+coronary+artery+disease:+results+from+1382+patients.en_HK
dc.identifier.emailLam, KF: hrntlkf@hkucc.hku.hken_HK
dc.identifier.emailSiu, DCW: cwdsiu@hkucc.hku.hken_HK
dc.identifier.emailYuen, MF: mfyuen@hkucc.hku.hken_HK
dc.identifier.emailWong, BCY: bcywong@hku.hken_HK
dc.identifier.authorityLam, KF=rp00718en_HK
dc.identifier.authoritySiu, DCW=rp00534en_HK
dc.identifier.authorityYuen, MF=rp00479en_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/j.1365-2036.2006.02958.xen_HK
dc.identifier.pmid16886920-
dc.identifier.scopuseid_2-s2.0-33745918313en_HK
dc.identifier.hkuros122188en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33745918313&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue3en_HK
dc.identifier.spage535en_HK
dc.identifier.epage539en_HK
dc.identifier.isiWOS:000239002800011-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChan, AOO=7403167965en_HK
dc.identifier.scopusauthoridLam, KF=8948421200en_HK
dc.identifier.scopusauthoridTong, T=7102587364en_HK
dc.identifier.scopusauthoridSiu, DCW=7006550690en_HK
dc.identifier.scopusauthoridJim, MH=6603860344en_HK
dc.identifier.scopusauthoridHui, WM=7103196477en_HK
dc.identifier.scopusauthoridLai, KC=7402135595en_HK
dc.identifier.scopusauthoridYuen, MF=7102031955en_HK
dc.identifier.scopusauthoridLam, SK=7402279473en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK
dc.identifier.citeulike761482-

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