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Article: Prediction of aortic augmentation index using radial pulse transmission-wave analysis

TitlePrediction of aortic augmentation index using radial pulse transmission-wave analysis
Authors
Issue Date2006
PublisherLippincott Williams & Wilkins, Ltd. The Journal's web site is located at http://www.jhypertension.com/
Citation
Journal Of Hypertension, 2006, v. 24 n. 4, p. 723-730 How to Cite?
AbstractObjective: Current arterial transfer functions have low capability in predicting aortic augmentation index (AIx) from radial pulse contour (RPC), because of the difficulty in accurately identifying the merging point (inflection point) in the derived aortic pulse contour (APC). We hypothesize that the formation time between each characteristic wave in APC is about one-third of ejection duration (ED/3). We sought to assess the accuracy of ED/3 in identifying the merging point in APC as compared to the conventional differential method. In addition, we sought to derive the AIx from RPC based on an arterial transfer function and the ED/3 method. Methods: APC and RPC sequences were measured digitally and simultaneously in 60 subjects (37 males; aged 60 ± 10 years). An ensemble-averaged RPC-to-APC transfer function was determined from 30 randomly selected subjects and was used to derive APC sequences in the 30 additional subjects. The accuracy of AIx predicted from RPC was determined. Results: In patients with a clearly identifiable merging point in APC, the ED/3 method identified the merging point of measured APC within 1.97 ± 0.60 ms of that identified by the conventional differential method, with identical AIx. The AIx and merging point of derived APC using the ED/3 method were also within 0.22 ± 1.01% and 1.81 ± 1.64 ms, respectively, of those of the measured APC using the conventional differential method. The accuracy of the predicted AIx was independent of age, sex, body-mass index and presence of hypertension. Conclusion: In a quiet resting state, the ED/3 is an alternative method for identifying the merging point in APC. In conjunction with transfer-function technique, AIx can be derived accurately from RPC. © 2006 Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/76409
ISSN
2015 Impact Factor: 5.062
2015 SCImago Journal Rankings: 2.193
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLau, EOYen_HK
dc.contributor.authorTse, HFen_HK
dc.contributor.authorChan, RHWen_HK
dc.contributor.authorChen, WHen_HK
dc.contributor.authorLee, PYen_HK
dc.contributor.authorLee, SWLen_HK
dc.contributor.authorChwang, ATen_HK
dc.contributor.authorLau, CPen_HK
dc.date.accessioned2010-09-06T07:20:55Z-
dc.date.available2010-09-06T07:20:55Z-
dc.date.issued2006en_HK
dc.identifier.citationJournal Of Hypertension, 2006, v. 24 n. 4, p. 723-730en_HK
dc.identifier.issn0263-6352en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76409-
dc.description.abstractObjective: Current arterial transfer functions have low capability in predicting aortic augmentation index (AIx) from radial pulse contour (RPC), because of the difficulty in accurately identifying the merging point (inflection point) in the derived aortic pulse contour (APC). We hypothesize that the formation time between each characteristic wave in APC is about one-third of ejection duration (ED/3). We sought to assess the accuracy of ED/3 in identifying the merging point in APC as compared to the conventional differential method. In addition, we sought to derive the AIx from RPC based on an arterial transfer function and the ED/3 method. Methods: APC and RPC sequences were measured digitally and simultaneously in 60 subjects (37 males; aged 60 ± 10 years). An ensemble-averaged RPC-to-APC transfer function was determined from 30 randomly selected subjects and was used to derive APC sequences in the 30 additional subjects. The accuracy of AIx predicted from RPC was determined. Results: In patients with a clearly identifiable merging point in APC, the ED/3 method identified the merging point of measured APC within 1.97 ± 0.60 ms of that identified by the conventional differential method, with identical AIx. The AIx and merging point of derived APC using the ED/3 method were also within 0.22 ± 1.01% and 1.81 ± 1.64 ms, respectively, of those of the measured APC using the conventional differential method. The accuracy of the predicted AIx was independent of age, sex, body-mass index and presence of hypertension. Conclusion: In a quiet resting state, the ED/3 is an alternative method for identifying the merging point in APC. In conjunction with transfer-function technique, AIx can be derived accurately from RPC. © 2006 Lippincott Williams & Wilkins.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins, Ltd. The Journal's web site is located at http://www.jhypertension.com/en_HK
dc.relation.ispartofJournal of Hypertensionen_HK
dc.rightsJournal of Hypertension. Copyright © Lippincott Williams & Wilkins, Ltd.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAorta - physiopathologyen_HK
dc.subject.meshBody Mass Indexen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshHypertension - diagnosis - physiopathologyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPulse - methodsen_HK
dc.subject.meshRadial Artery - physiopathologyen_HK
dc.subject.meshReproducibility of Resultsen_HK
dc.titlePrediction of aortic augmentation index using radial pulse transmission-wave analysisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0263-6352&volume=24&issue=4&spage=723&epage=730&date=2006&atitle=Prediction+of+aortic+augmentation+index+using+radial+pulse+transmission-wave+analysisen_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/01.hjh.0000217855.74498.4fen_HK
dc.identifier.pmid16531801-
dc.identifier.scopuseid_2-s2.0-33645513277en_HK
dc.identifier.hkuros117290en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645513277&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue4en_HK
dc.identifier.spage723en_HK
dc.identifier.epage730en_HK
dc.identifier.isiWOS:000236596300018-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLau, EOY=12800522700en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.scopusauthoridChan, RHW=7403110832en_HK
dc.identifier.scopusauthoridChen, WH=7409637978en_HK
dc.identifier.scopusauthoridLee, PY=8933949600en_HK
dc.identifier.scopusauthoridLee, SWL=23990967700en_HK
dc.identifier.scopusauthoridChwang, AT=7005883964en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK

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