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Article: An evaluation of a rapid urine test for the diagnosis of Helicobacter pylori infection in the Chinese population

TitleAn evaluation of a rapid urine test for the diagnosis of Helicobacter pylori infection in the Chinese population
Authors
Issue Date2002
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
Citation
Alimentary Pharmacology And Therapeutics, 2002, v. 16 n. 4, p. 813-817 How to Cite?
AbstractBackground: A new rapid urine test was developed to detect anti-Helicobacter pylori antibody in urine using the principle of immunochromatography. The accuracy of this test in the Chinese population remains to be defined. Aim: To evaluate a new rapid urine test for the diagnosis of H. pylori infection in the Chinese population. Methods: Eligible patients without previous treatment of H. pylori were recruited. In-house rapid urease test and histology were used as the gold standard. The rapid urine test (RAPIRUN H. pylori antibody) was performed and the results were compared with the gold standard. Results: One hundred and twenty-three patients were eligible for analysis and 61 (50%) were H. pylori positive by the gold standard. The rapid urine test showed a sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 96.7%, 95.2%, 95.2%, 96.7% and 95.9%, respectively. Results were obtained within 20 min and no special laboratory support was required. Conclusions: The rapid urine test by immunochromatography is highly accurate for the diagnosis of H. pylori infection in untreated Chinese patients.
Persistent Identifierhttp://hdl.handle.net/10722/76350
ISSN
2015 Impact Factor: 6.32
2015 SCImago Journal Rankings: 2.833
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, WMen_HK
dc.contributor.authorWong, BCYen_HK
dc.contributor.authorXia, HHXen_HK
dc.contributor.authorTang, VSYen_HK
dc.contributor.authorLai, KCen_HK
dc.contributor.authorHu, WHCen_HK
dc.contributor.authorYuen, MFen_HK
dc.contributor.authorChan, CKen_HK
dc.contributor.authorLam, SKen_HK
dc.date.accessioned2010-09-06T07:20:18Z-
dc.date.available2010-09-06T07:20:18Z-
dc.date.issued2002en_HK
dc.identifier.citationAlimentary Pharmacology And Therapeutics, 2002, v. 16 n. 4, p. 813-817en_HK
dc.identifier.issn0269-2813en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76350-
dc.description.abstractBackground: A new rapid urine test was developed to detect anti-Helicobacter pylori antibody in urine using the principle of immunochromatography. The accuracy of this test in the Chinese population remains to be defined. Aim: To evaluate a new rapid urine test for the diagnosis of H. pylori infection in the Chinese population. Methods: Eligible patients without previous treatment of H. pylori were recruited. In-house rapid urease test and histology were used as the gold standard. The rapid urine test (RAPIRUN H. pylori antibody) was performed and the results were compared with the gold standard. Results: One hundred and twenty-three patients were eligible for analysis and 61 (50%) were H. pylori positive by the gold standard. The rapid urine test showed a sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 96.7%, 95.2%, 95.2%, 96.7% and 95.9%, respectively. Results were obtained within 20 min and no special laboratory support was required. Conclusions: The rapid urine test by immunochromatography is highly accurate for the diagnosis of H. pylori infection in untreated Chinese patients.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APTen_HK
dc.relation.ispartofAlimentary Pharmacology and Therapeuticsen_HK
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.en_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshAntibodies, Bacterial - urineen_HK
dc.subject.meshChina - epidemiologyen_HK
dc.subject.meshEvaluation Studies as Topicen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHelicobacter Infections - urineen_HK
dc.subject.meshHelicobacter pylori - enzymology - immunologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshImmunochemistryen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshReagent Kits, Diagnosticen_HK
dc.subject.meshSensitivity and Specificityen_HK
dc.subject.meshUrease - metabolismen_HK
dc.titleAn evaluation of a rapid urine test for the diagnosis of Helicobacter pylori infection in the Chinese populationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-2813&volume=16&issue=4&spage=813&epage=817&date=2002&atitle=An+evaluation+of+a+rapid+urine+test+for+the+diagnosis+of+Helicobacter+pylori+infection+in+the+Chinese+populationen_HK
dc.identifier.emailWong, BCY:bcywong@hku.hken_HK
dc.identifier.emailYuen, MF:mfyuen@hkucc.hku.hken_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.identifier.authorityYuen, MF=rp00479en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1046/j.1365-2036.2002.01235.xen_HK
dc.identifier.pmid11929401-
dc.identifier.scopuseid_2-s2.0-0036114271en_HK
dc.identifier.hkuros72101en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036114271&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue4en_HK
dc.identifier.spage813en_HK
dc.identifier.epage817en_HK
dc.identifier.isiWOS:000175115300020-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, WM=7403972413en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK
dc.identifier.scopusauthoridXia, HHX=8757161400en_HK
dc.identifier.scopusauthoridTang, VSY=6701711948en_HK
dc.identifier.scopusauthoridLai, KC=7402135595en_HK
dc.identifier.scopusauthoridHu, WHC=25932937100en_HK
dc.identifier.scopusauthoridYuen, MF=7102031955en_HK
dc.identifier.scopusauthoridChan, CK=7404813824en_HK
dc.identifier.scopusauthoridLam, SK=7402279473en_HK

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