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Article: Effects of different atrioventricular intervals during dual-site right atrial pacing on left atrial mechanical function

TitleEffects of different atrioventricular intervals during dual-site right atrial pacing on left atrial mechanical function
Authors
Issue Date2000
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1
Citation
Pace - Pacing And Clinical Electrophysiology, 2000, v. 23 n. 11 II, p. 1748-1751 How to Cite?
AbstractRecent studies have suggested that dual-site right atrial (RA) pacing via the high RA and coronary sinus ostium (CSos) prevents atrial fibrillation (AF). However, the programming of the atrioventricular (AV) interval associated with optimal left atrial (LA) mechanical function during high RA and dual-site RA pacing has not been defined. LA mechanical function was studied by measuring transmittal pulsed Doppler echocardiographic peak A wave velocity and percent A wave filling, in six women and three men, 67 ± 8 years of age, who had received dual-site RA pacemakers in a randomized study. Serial echocardiographic measurements were performed during high RA or dual-site RA pacing at 80 beats/min with AV intervals of 50, 100, 150, or 200 ms tested in random order. High RA and dual-site RA pacing at an AV interval of 50 ms were associated with significantly lower peak A wave velocity and percent A wave filling, compared to the other AV intervals (all P < 0.05). Compared with high RA pacing, dual-site RA pacing was associated with significantly higher peak A wave velocity (85 ± 12 vs 72 ± 17 cm/s, P = 0.04) and percent A wave filling (24 ± 3 vs 20 ± 4 %, P = 0.02) at an AV interval of 100 ms, but a lower peak A wave velocity at an AV interval of 200 ms (77 ± 10 vs 84 ± 8 cm/s, P = 0.004). In conclusion, variations in the AV interval during atrial pacing have significant effects on LA function. As a consequence of altered atrial activation, the AV interval associated with optimal LA mechanical function during dual-site RA pacing was significantly shorter than that during RA pacing. This observation has important implications with respect to the programming of dual-site RA pacemakers implanted to prevent AF for hemodynamic purpose.
Persistent Identifierhttp://hdl.handle.net/10722/76267
ISSN
2015 Impact Factor: 1.156
2015 SCImago Journal Rankings: 0.662
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_HK
dc.contributor.authorTse, HFen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorHettrick, DAen_HK
dc.contributor.authorMehra, Ren_HK
dc.date.accessioned2010-09-06T07:19:24Z-
dc.date.available2010-09-06T07:19:24Z-
dc.date.issued2000en_HK
dc.identifier.citationPace - Pacing And Clinical Electrophysiology, 2000, v. 23 n. 11 II, p. 1748-1751en_HK
dc.identifier.issn0147-8389en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76267-
dc.description.abstractRecent studies have suggested that dual-site right atrial (RA) pacing via the high RA and coronary sinus ostium (CSos) prevents atrial fibrillation (AF). However, the programming of the atrioventricular (AV) interval associated with optimal left atrial (LA) mechanical function during high RA and dual-site RA pacing has not been defined. LA mechanical function was studied by measuring transmittal pulsed Doppler echocardiographic peak A wave velocity and percent A wave filling, in six women and three men, 67 ± 8 years of age, who had received dual-site RA pacemakers in a randomized study. Serial echocardiographic measurements were performed during high RA or dual-site RA pacing at 80 beats/min with AV intervals of 50, 100, 150, or 200 ms tested in random order. High RA and dual-site RA pacing at an AV interval of 50 ms were associated with significantly lower peak A wave velocity and percent A wave filling, compared to the other AV intervals (all P < 0.05). Compared with high RA pacing, dual-site RA pacing was associated with significantly higher peak A wave velocity (85 ± 12 vs 72 ± 17 cm/s, P = 0.04) and percent A wave filling (24 ± 3 vs 20 ± 4 %, P = 0.02) at an AV interval of 100 ms, but a lower peak A wave velocity at an AV interval of 200 ms (77 ± 10 vs 84 ± 8 cm/s, P = 0.004). In conclusion, variations in the AV interval during atrial pacing have significant effects on LA function. As a consequence of altered atrial activation, the AV interval associated with optimal LA mechanical function during dual-site RA pacing was significantly shorter than that during RA pacing. This observation has important implications with respect to the programming of dual-site RA pacemakers implanted to prevent AF for hemodynamic purpose.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1en_HK
dc.relation.ispartofPACE - Pacing and Clinical Electrophysiologyen_HK
dc.subject.meshAgeden_HK
dc.subject.meshAtrial Fibrillation - complications - therapyen_HK
dc.subject.meshAtrial Function, Leften_HK
dc.subject.meshAtrial Function, Righten_HK
dc.subject.meshCardiac Outputen_HK
dc.subject.meshCardiac Pacing, Artificial - methodsen_HK
dc.subject.meshEchocardiographyen_HK
dc.subject.meshEchocardiography, Doppleren_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHeart Atria - ultrasonographyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshPacemaker, Artificialen_HK
dc.subject.meshReaction Timeen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.subject.meshVentricular Functionen_HK
dc.titleEffects of different atrioventricular intervals during dual-site right atrial pacing on left atrial mechanical functionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0147-8389&volume=23&spage=1748&epage=1751&date=2000&atitle=Effects+of+different+atrioventricular+intervals+during+dual-site+right+atrial+pacing+on+left+atrial+mechanical+functionen_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid11139916-
dc.identifier.scopuseid_2-s2.0-0033674985en_HK
dc.identifier.hkuros56331en_HK
dc.identifier.hkuros100910-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033674985&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume23en_HK
dc.identifier.issue11 IIen_HK
dc.identifier.spage1748en_HK
dc.identifier.epage1751en_HK
dc.identifier.isiWOS:000165755900011-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHo, PC=24469553100en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK
dc.identifier.scopusauthoridHettrick, DA=7007092525en_HK
dc.identifier.scopusauthoridMehra, R=7201915459en_HK

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