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Article: Fabrication and characterisation of polymer and composite scaffolds based on polyhydroxybutyrate and polyhydroxybutyrate-co-hydroxyvalerate

TitleFabrication and characterisation of polymer and composite scaffolds based on polyhydroxybutyrate and polyhydroxybutyrate-co-hydroxyvalerate
Authors
KeywordsBiodegradable polymer
Polyhydroxybutyrate-co-valerate
Porosity
Scaffold
Issue Date2007
PublisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net
Citation
Key Engineering Materials, 2007, v. 334-335 II, p. 1229-1232 How to Cite?
AbstractThis paper reports the fabrication and characterization of three-dimensional, highly porous polyhydroxybutyrate (PHB), polyhydroxybutyrate- co-valerate (PHBV) and composite scaffolds made by the emulsion freezing / freezing-drying technique. Freeze-drying of the polymer/solvent/ water phase emulsions produced hard and tough scaffolds with interconnected pores. The effects of the fabrication parameters such as polymer concentration in emulsions and emulsion stabilizer were examined and optimized. The density of polymer scaffolds was found to increase with an increasing polymer concentration. Structural analyses of selected samples using scanning electron microscopy indicated that the scaffolds had pore sizes ranging from several microns to a few hundred microns. The porosity of scaffolds of up to 85% was achieved and it increased with a decreasing polymer concentration. It was found that mechanical properties of composite scaffolds increased with the increasing amount of hydroxyapatite (HA) incorporated in the scaffolds.
Persistent Identifierhttp://hdl.handle.net/10722/75725
ISSN
2005 Impact Factor: 0.224
2015 SCImago Journal Rankings: 0.173
References

 

DC FieldValueLanguage
dc.contributor.authorSultana, Nen_HK
dc.contributor.authorWang, Men_HK
dc.date.accessioned2010-09-06T07:13:57Z-
dc.date.available2010-09-06T07:13:57Z-
dc.date.issued2007en_HK
dc.identifier.citationKey Engineering Materials, 2007, v. 334-335 II, p. 1229-1232en_HK
dc.identifier.issn1013-9826en_HK
dc.identifier.urihttp://hdl.handle.net/10722/75725-
dc.description.abstractThis paper reports the fabrication and characterization of three-dimensional, highly porous polyhydroxybutyrate (PHB), polyhydroxybutyrate- co-valerate (PHBV) and composite scaffolds made by the emulsion freezing / freezing-drying technique. Freeze-drying of the polymer/solvent/ water phase emulsions produced hard and tough scaffolds with interconnected pores. The effects of the fabrication parameters such as polymer concentration in emulsions and emulsion stabilizer were examined and optimized. The density of polymer scaffolds was found to increase with an increasing polymer concentration. Structural analyses of selected samples using scanning electron microscopy indicated that the scaffolds had pore sizes ranging from several microns to a few hundred microns. The porosity of scaffolds of up to 85% was achieved and it increased with a decreasing polymer concentration. It was found that mechanical properties of composite scaffolds increased with the increasing amount of hydroxyapatite (HA) incorporated in the scaffolds.en_HK
dc.languageengen_HK
dc.publisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.neten_HK
dc.relation.ispartofKey Engineering Materialsen_HK
dc.rightsKey Engineering Materials. Copyright © Trans Tech Publications Ltd.en_HK
dc.subjectBiodegradable polymeren_HK
dc.subjectPolyhydroxybutyrate-co-valerateen_HK
dc.subjectPorosityen_HK
dc.subjectScaffolden_HK
dc.titleFabrication and characterisation of polymer and composite scaffolds based on polyhydroxybutyrate and polyhydroxybutyrate-co-hydroxyvalerateen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1013-9826&volume=334-335 &spage=1229&epage=1232&date=2007&atitle=Fabrication+and+characterisation+of+polymer+and+composite+scaffolds+based+on+polyhydroxybutyrate+and+polyhydroxybutyrate-co-hydroxyvalerateen_HK
dc.identifier.emailWang, M:memwang@hku.hken_HK
dc.identifier.authorityWang, M=rp00185en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-33847042277en_HK
dc.identifier.hkuros132983en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33847042277&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume334-335 IIen_HK
dc.identifier.spage1229en_HK
dc.identifier.epage1232en_HK
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridSultana, N=15849681300en_HK
dc.identifier.scopusauthoridWang, M=15749714100en_HK

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