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Article: Study of myocardial fiber pathway using magnetic resonance diffusion tensor imaging

TitleStudy of myocardial fiber pathway using magnetic resonance diffusion tensor imaging
Authors
KeywordsDiffusion tensor imaging
Helix angle
Myocardial fiber connectivity
Myocardial fiber orientation
Myocardial fiber pathway
Issue Date2007
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/mri
Citation
Magnetic Resonance Imaging, 2007, v. 25 n. 7, p. 1048-1057 How to Cite?
AbstractThe purpose of this study was to investigate myocardial fiber pathway distribution in order to provide supplemental information on myocardial fiber architecture and cardiac mechanics. Diffusion tensor imaging (DTI) with medium diffusion resolution (15 directions) was performed on normal canine heart samples (N=6) fixed in formalin. With the use of diffusion tensor fiber tracking, left ventricle (LV) myocardial fiber pathways and helix angles were computed pixel by pixel at short-axis slices from base to apex. Distribution of DTI-tracked fiber pathway length and number was analyzed quantitatively as a function of fiber helix angle in step of 9°. The long fiber pathways were found to have small helix angles. They are mostly distributed in the middle myocardium and run circumferentially. Fiber pathways tracked at the middle and upper LV are generally longer than those near the apex. Majority of fiber pathways have small helix angles between -20° and 20°, dominating the fiber architecture in myocardium. Likely, such myocardial fiber pathway measurement by DTI may reflect the spatial connectiveness or connectivity of elastic myofiber bundles along their preferential pathway of electromechanical activation. The dominance of the long and circumferentially running fiber pathways found in the study may explain the circumferential predominance in left ventricular contraction. © 2007 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/73877
ISSN
2015 Impact Factor: 1.98
2015 SCImago Journal Rankings: 1.139
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWu, EXen_HK
dc.contributor.authorWu, Yen_HK
dc.contributor.authorTang, Hen_HK
dc.contributor.authorWang, Jen_HK
dc.contributor.authorYang, Jen_HK
dc.contributor.authorNg, MCen_HK
dc.contributor.authorYang, ESen_HK
dc.contributor.authorChan, CWen_HK
dc.contributor.authorZhu, Sen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorTse, HFen_HK
dc.date.accessioned2010-09-06T06:55:37Z-
dc.date.available2010-09-06T06:55:37Z-
dc.date.issued2007en_HK
dc.identifier.citationMagnetic Resonance Imaging, 2007, v. 25 n. 7, p. 1048-1057en_HK
dc.identifier.issn0730-725Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/73877-
dc.description.abstractThe purpose of this study was to investigate myocardial fiber pathway distribution in order to provide supplemental information on myocardial fiber architecture and cardiac mechanics. Diffusion tensor imaging (DTI) with medium diffusion resolution (15 directions) was performed on normal canine heart samples (N=6) fixed in formalin. With the use of diffusion tensor fiber tracking, left ventricle (LV) myocardial fiber pathways and helix angles were computed pixel by pixel at short-axis slices from base to apex. Distribution of DTI-tracked fiber pathway length and number was analyzed quantitatively as a function of fiber helix angle in step of 9°. The long fiber pathways were found to have small helix angles. They are mostly distributed in the middle myocardium and run circumferentially. Fiber pathways tracked at the middle and upper LV are generally longer than those near the apex. Majority of fiber pathways have small helix angles between -20° and 20°, dominating the fiber architecture in myocardium. Likely, such myocardial fiber pathway measurement by DTI may reflect the spatial connectiveness or connectivity of elastic myofiber bundles along their preferential pathway of electromechanical activation. The dominance of the long and circumferentially running fiber pathways found in the study may explain the circumferential predominance in left ventricular contraction. © 2007 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/mrien_HK
dc.relation.ispartofMagnetic Resonance Imagingen_HK
dc.subjectDiffusion tensor imagingen_HK
dc.subjectHelix angleen_HK
dc.subjectMyocardial fiber connectivityen_HK
dc.subjectMyocardial fiber orientationen_HK
dc.subjectMyocardial fiber pathwayen_HK
dc.subject.meshDiffusion Magnetic Resonance Imaging-
dc.subject.meshHeart - anatomy and histology-
dc.subject.meshImaging, Three-Dimensional-
dc.subject.meshMuscle Fibers, Skeletal-
dc.subject.meshPapillary Muscles - anatomy and histology-
dc.titleStudy of myocardial fiber pathway using magnetic resonance diffusion tensor imagingen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0730-725X&volume=25&issue=7&spage=1048&epage=1057&date=2007&atitle=Study+of+myocardial+fiber+pathway+using+magnetic+resonance+diffusion+tensor+imagingen_HK
dc.identifier.emailWu, EX:ewu1@hkucc.hku.hken_HK
dc.identifier.emailYang, ES:esyang@hkueee.hku.hken_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.identifier.authorityYang, ES=rp00199en_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.mri.2006.12.008en_HK
dc.identifier.pmid17707167en_HK
dc.identifier.scopuseid_2-s2.0-34547732836en_HK
dc.identifier.hkuros141484en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34547732836&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume25en_HK
dc.identifier.issue7en_HK
dc.identifier.spage1048en_HK
dc.identifier.epage1057en_HK
dc.identifier.isiWOS:000249056200005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWu, EX=7202128034en_HK
dc.identifier.scopusauthoridWu, Y=8940205500en_HK
dc.identifier.scopusauthoridTang, H=36827331000en_HK
dc.identifier.scopusauthoridWang, J=8061150000en_HK
dc.identifier.scopusauthoridYang, J=10041733800en_HK
dc.identifier.scopusauthoridNg, MC=36747599500en_HK
dc.identifier.scopusauthoridYang, ES=7202021229en_HK
dc.identifier.scopusauthoridChan, CW=7404813871en_HK
dc.identifier.scopusauthoridZhu, S=55237337600en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK

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