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Article: Three-dimensional triple-quantum-filtered 23Na imaging of in vivo human brain

TitleThree-dimensional triple-quantum-filtered 23Na imaging of in vivo human brain
Authors
KeywordsBrain
RF inhomogeneity
Sodium imaging
Three pulse filter
Triple-quantum imaging
Issue Date1999
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0740-3194/
Citation
Magnetic Resonance In Medicine, 1999, v. 42 n. 6, p. 1146-1154 How to Cite?
AbstractA scheme for the generation of three-dimensional, triple-quantum- filtered (TQ) sodium images from normal human brain is presented. In this approach, a three-pulse, six-step, coherence transfer filter was used in conjunction with a fast twisted projection imaging sequence to generate spatial maps of the TQ signal across the entire brain. It is demonstrated, theoretically as well as experimentally, that the use of the three-pulse coherence filter leads to TQ sodium images in which the dependence of the image intensity on the spatial variation of the flip angle is less pronounced than it is in the 'standard,' four-pulse, TQ filter. Correction for the variation of the TQ signal intensity across the field of view because of radio-frequency (RF) inhomogeneity is straightforward with this approach. This imaging scheme allows the generation of RF inhomogeneity-corrected, TQ, sodium images from human brain at moderate field strength (3.0 T) in times acceptable for routine clinical examinations (20 minutes).
Persistent Identifierhttp://hdl.handle.net/10722/73610
ISSN
2015 Impact Factor: 3.782
2015 SCImago Journal Rankings: 2.197
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHancu, Ien_HK
dc.contributor.authorBoada, FEen_HK
dc.contributor.authorShen, GXen_HK
dc.date.accessioned2010-09-06T06:53:02Z-
dc.date.available2010-09-06T06:53:02Z-
dc.date.issued1999en_HK
dc.identifier.citationMagnetic Resonance In Medicine, 1999, v. 42 n. 6, p. 1146-1154en_HK
dc.identifier.issn0740-3194en_HK
dc.identifier.urihttp://hdl.handle.net/10722/73610-
dc.description.abstractA scheme for the generation of three-dimensional, triple-quantum- filtered (TQ) sodium images from normal human brain is presented. In this approach, a three-pulse, six-step, coherence transfer filter was used in conjunction with a fast twisted projection imaging sequence to generate spatial maps of the TQ signal across the entire brain. It is demonstrated, theoretically as well as experimentally, that the use of the three-pulse coherence filter leads to TQ sodium images in which the dependence of the image intensity on the spatial variation of the flip angle is less pronounced than it is in the 'standard,' four-pulse, TQ filter. Correction for the variation of the TQ signal intensity across the field of view because of radio-frequency (RF) inhomogeneity is straightforward with this approach. This imaging scheme allows the generation of RF inhomogeneity-corrected, TQ, sodium images from human brain at moderate field strength (3.0 T) in times acceptable for routine clinical examinations (20 minutes).en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0740-3194/en_HK
dc.relation.ispartofMagnetic Resonance in Medicineen_HK
dc.rightsMagnetic Resonance in Medicine. Copyright © John Wiley & Sons, Inc.en_HK
dc.subjectBrainen_HK
dc.subjectRF inhomogeneityen_HK
dc.subjectSodium imagingen_HK
dc.subjectThree pulse filteren_HK
dc.subjectTriple-quantum imagingen_HK
dc.titleThree-dimensional triple-quantum-filtered 23Na imaging of in vivo human brainen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0740-3194&volume=42&spage=pp1146&epage=1154&date=2000&atitle=Three+dimensional+triple-quantum-filtered+23Na+imaging+of+in+vivo+human+brainen_HK
dc.identifier.emailShen, GX: gxshen@eee.hku.hken_HK
dc.identifier.authorityShen, GX=rp00166en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/(SICI)1522-2594(199912)42:6<1146::AID-MRM20>3.0.CO;2-Sen_HK
dc.identifier.pmid10571937en_HK
dc.identifier.scopuseid_2-s2.0-0032756878en_HK
dc.identifier.hkuros52489en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032756878&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume42en_HK
dc.identifier.issue6en_HK
dc.identifier.spage1146en_HK
dc.identifier.epage1154en_HK
dc.identifier.isiWOS:000083959300020-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHancu, I=6602568486en_HK
dc.identifier.scopusauthoridBoada, FE=7004585213en_HK
dc.identifier.scopusauthoridShen, GX=7401967224en_HK

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