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Article: Interleaved water and fat imaging and applications to lipid quantitation using the gradient reversal technique

TitleInterleaved water and fat imaging and applications to lipid quantitation using the gradient reversal technique
Authors
Issue Date2007
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/
Citation
Journal Of Magnetic Resonance Imaging, 2007, v. 26 n. 4, p. 1064-1070 How to Cite?
AbstractPurpose: To implement and evaluate the gradient reversal-based chemical shift imaging technique to obtain qualitative and quantitative spatially-registered fat and water images with high imaging efficiency at very high field. Materials and Methods: A multiecho gradient reversal-based sequence allowing interleaved water-fat imaging during a single acquisition and quantitation of fat/water content is presented. The sequence was optimized and implemented at 11.7T. The quantitation was verified with water-fat phantoms and applied to lipid measurement in an in vivo mouse model. Results: Results from phantoms, in vivo lipid measurement in mouse liver and hind limb muscle, and ex vivo rat knee imaging experiments demonstrated the robustness and high selectivity of this technique for interleaved and quantitative water and fat imaging at very high field. Conclusion: The proposed MRI technique permits interleaved water and fat imaging, with which spectrally well-separated water and fat images at the identical slice locations could be obtained in a single acquisition without increasing scan time. The technique could be used for in vivo quantitative mapping of lipid content and applied to investigations using small animal experiment models. © 2007 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/73609
ISSN
2015 Impact Factor: 3.25
2015 SCImago Journal Rankings: 1.683
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTang, Hen_HK
dc.contributor.authorWu, EXen_HK
dc.contributor.authorKennan, Ren_HK
dc.contributor.authorLiu, Hen_HK
dc.contributor.authorWilliams, DSen_HK
dc.date.accessioned2010-09-06T06:53:02Z-
dc.date.available2010-09-06T06:53:02Z-
dc.date.issued2007en_HK
dc.identifier.citationJournal Of Magnetic Resonance Imaging, 2007, v. 26 n. 4, p. 1064-1070en_HK
dc.identifier.issn1053-1807en_HK
dc.identifier.urihttp://hdl.handle.net/10722/73609-
dc.description.abstractPurpose: To implement and evaluate the gradient reversal-based chemical shift imaging technique to obtain qualitative and quantitative spatially-registered fat and water images with high imaging efficiency at very high field. Materials and Methods: A multiecho gradient reversal-based sequence allowing interleaved water-fat imaging during a single acquisition and quantitation of fat/water content is presented. The sequence was optimized and implemented at 11.7T. The quantitation was verified with water-fat phantoms and applied to lipid measurement in an in vivo mouse model. Results: Results from phantoms, in vivo lipid measurement in mouse liver and hind limb muscle, and ex vivo rat knee imaging experiments demonstrated the robustness and high selectivity of this technique for interleaved and quantitative water and fat imaging at very high field. Conclusion: The proposed MRI technique permits interleaved water and fat imaging, with which spectrally well-separated water and fat images at the identical slice locations could be obtained in a single acquisition without increasing scan time. The technique could be used for in vivo quantitative mapping of lipid content and applied to investigations using small animal experiment models. © 2007 Wiley-Liss, Inc.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/1053-1807/en_HK
dc.relation.ispartofJournal of Magnetic Resonance Imagingen_HK
dc.rightsJournal of Magnetic Resonance Imaging. Copyright © John Wiley & Sons, Inc.en_HK
dc.subject.meshAdipose Tissue - metabolismen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshImage Processing, Computer-Assisteden_HK
dc.subject.meshLipids - chemistryen_HK
dc.subject.meshLiver - metabolismen_HK
dc.subject.meshMagnetic Resonance Imaging - methodsen_HK
dc.subject.meshMiceen_HK
dc.subject.meshMice, Obeseen_HK
dc.subject.meshNormal Distributionen_HK
dc.subject.meshPhantoms, Imagingen_HK
dc.subject.meshProtonsen_HK
dc.subject.meshWater - chemistryen_HK
dc.titleInterleaved water and fat imaging and applications to lipid quantitation using the gradient reversal techniqueen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1053-1807&volume=26&spage=1064&epage=1070&date=2007&atitle=Interleaved+water+and+fat+imaging+and+applications+to+lipid+quantitation+using+the+gradient+reversal+techniqueen_HK
dc.identifier.emailWu, EX:ewu1@hkucc.hku.hken_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/jmri.21055en_HK
dc.identifier.pmid17896353-
dc.identifier.scopuseid_2-s2.0-35148879271en_HK
dc.identifier.hkuros141485en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-35148879271&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume26en_HK
dc.identifier.issue4en_HK
dc.identifier.spage1064en_HK
dc.identifier.epage1070en_HK
dc.identifier.isiWOS:000249898800030-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTang, H=36827331000en_HK
dc.identifier.scopusauthoridWu, EX=7202128034en_HK
dc.identifier.scopusauthoridKennan, R=7004649532en_HK
dc.identifier.scopusauthoridLiu, H=7409753420en_HK
dc.identifier.scopusauthoridWilliams, DS=16154657700en_HK

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