File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Neuronal cholinergic control is involved in the modification of cardiac activity and circulation induced by waterborne copper in the chiton Acanthopleura japonica

TitleNeuronal cholinergic control is involved in the modification of cardiac activity and circulation induced by waterborne copper in the chiton Acanthopleura japonica
Authors
KeywordsCardiac activity
Chitons
Cholinergic antagonists
Copper
Molluscs
Tetrodotoxin
Issue Date2006
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jembe
Citation
Journal Of Experimental Marine Biology And Ecology, 2006, v. 338 n. 1, p. 43-49 How to Cite?
AbstractCardiac activity and arterial throughput were studied in the chiton Acanthopleura japonica following exposure to waterborne copper. In order to understand the mechanism of copper action, exposure to the metal was combined with injection of the sodium channel blocker tetrodotoxin, and two cholinergic antagonists, atropine and benzoquinonium. Copper (0.25, 0.33, 0.5, 1 mg l- 1; 3 h) induced a concentration dependent reduction in heart rate and, at the highest concentration, a reversible arrest of heartbeat. Tetrodotoxin (1 μM), atropine (20 μM) and benzoquinonium (5 μM) significantly antagonized the reduction in heart rate elicited by copper (0.33 mg l- 1, 3 h). As copper also induced a reduction of heartbeat amplitude and consequent arterial throughput, these results support the hypothesis that the metal activates an extrinsic cholinergic control of heart activity in chitons, resulting in a decrease in haemolymph circulation and, consequently, of metal uptake through the gills. © 2006 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/73411
ISSN
2015 Impact Factor: 1.796
2015 SCImago Journal Rankings: 1.029
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorBini, Gen_HK
dc.contributor.authorWilliams, GAen_HK
dc.contributor.authorChelazzi, Gen_HK
dc.date.accessioned2010-09-06T06:51:01Z-
dc.date.available2010-09-06T06:51:01Z-
dc.date.issued2006en_HK
dc.identifier.citationJournal Of Experimental Marine Biology And Ecology, 2006, v. 338 n. 1, p. 43-49en_HK
dc.identifier.issn0022-0981en_HK
dc.identifier.urihttp://hdl.handle.net/10722/73411-
dc.description.abstractCardiac activity and arterial throughput were studied in the chiton Acanthopleura japonica following exposure to waterborne copper. In order to understand the mechanism of copper action, exposure to the metal was combined with injection of the sodium channel blocker tetrodotoxin, and two cholinergic antagonists, atropine and benzoquinonium. Copper (0.25, 0.33, 0.5, 1 mg l- 1; 3 h) induced a concentration dependent reduction in heart rate and, at the highest concentration, a reversible arrest of heartbeat. Tetrodotoxin (1 μM), atropine (20 μM) and benzoquinonium (5 μM) significantly antagonized the reduction in heart rate elicited by copper (0.33 mg l- 1, 3 h). As copper also induced a reduction of heartbeat amplitude and consequent arterial throughput, these results support the hypothesis that the metal activates an extrinsic cholinergic control of heart activity in chitons, resulting in a decrease in haemolymph circulation and, consequently, of metal uptake through the gills. © 2006 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jembeen_HK
dc.relation.ispartofJournal of Experimental Marine Biology and Ecologyen_HK
dc.rightsJournal of Experimental Marine Biology and Ecology. Copyright © Elsevier BV.en_HK
dc.subjectCardiac activityen_HK
dc.subjectChitonsen_HK
dc.subjectCholinergic antagonistsen_HK
dc.subjectCopperen_HK
dc.subjectMolluscsen_HK
dc.subjectTetrodotoxinen_HK
dc.titleNeuronal cholinergic control is involved in the modification of cardiac activity and circulation induced by waterborne copper in the chiton Acanthopleura japonicaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-0981&volume=338&spage=43&epage=49&date=2006&atitle=Neuronal+cholinergic+control+is+involved+in+the+modification+of+cardiac+activity+and+circulation+induced+by+waterborne+copper+in+the+chiton+Acanthopleura+japonicaen_HK
dc.identifier.emailWilliams, GA: hrsbwga@hkucc.hku.hken_HK
dc.identifier.authorityWilliams, GA=rp00804en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jembe.2006.06.026en_HK
dc.identifier.scopuseid_2-s2.0-33748458047en_HK
dc.identifier.hkuros120977en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33748458047&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume338en_HK
dc.identifier.issue1en_HK
dc.identifier.spage43en_HK
dc.identifier.epage49en_HK
dc.identifier.isiWOS:000241016200004-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridBini, G=9238310300en_HK
dc.identifier.scopusauthoridWilliams, GA=7406082821en_HK
dc.identifier.scopusauthoridChelazzi, G=7004590102en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats