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Article: Diffusion magnetic resonance imaging findings in acute methotrexate neurotoxicity
Title | Diffusion magnetic resonance imaging findings in acute methotrexate neurotoxicity |
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Authors | |
Keywords | Diffusion magnetic resonance imaging Methotrexate Neurotoxicity syndromes Osteosarcoma |
Issue Date | 2005 |
Publisher | Scientific Communications International Ltd. The Journal's web site is located at http://www.hkcr.org/ |
Citation | Journal Of The Hong Kong College Of Radiologists, 2005, v. 8 n. 4, p. 250-253 How to Cite? |
Abstract | We present the case of a patient with right fibular osteosarcoma, who was treated with multiple chemotherapeutic agents, including methotrexate, according to the Hong Kong Paediatric Haematology and Oncology Study Group osteogenic sarcoma protocol After eight weeks of treatment, he developed acute neurological symptoms, paralleled by diffusion magnetic resonance imaging brain scan findings of restricted diffusion in the white matter within 24 hours of symptom onset. Subsequently, three more sequential magnetic resonance imaging brain scans were performed, with the last scan, performed at five months after symptom onset, showing regression of the lesion. © 2005 Hong Kong College of Radiologists. |
Persistent Identifier | http://hdl.handle.net/10722/72387 |
ISSN | |
References |
DC Field | Value | Language |
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dc.contributor.author | Tsang, DSF | en_HK |
dc.contributor.author | Khong, PL | en_HK |
dc.date.accessioned | 2010-09-06T06:41:12Z | - |
dc.date.available | 2010-09-06T06:41:12Z | - |
dc.date.issued | 2005 | en_HK |
dc.identifier.citation | Journal Of The Hong Kong College Of Radiologists, 2005, v. 8 n. 4, p. 250-253 | en_HK |
dc.identifier.issn | 1029-5097 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/72387 | - |
dc.description.abstract | We present the case of a patient with right fibular osteosarcoma, who was treated with multiple chemotherapeutic agents, including methotrexate, according to the Hong Kong Paediatric Haematology and Oncology Study Group osteogenic sarcoma protocol After eight weeks of treatment, he developed acute neurological symptoms, paralleled by diffusion magnetic resonance imaging brain scan findings of restricted diffusion in the white matter within 24 hours of symptom onset. Subsequently, three more sequential magnetic resonance imaging brain scans were performed, with the last scan, performed at five months after symptom onset, showing regression of the lesion. © 2005 Hong Kong College of Radiologists. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Scientific Communications International Ltd. The Journal's web site is located at http://www.hkcr.org/ | en_HK |
dc.relation.ispartof | Journal of the Hong Kong College of Radiologists | en_HK |
dc.subject | Diffusion magnetic resonance imaging | en_HK |
dc.subject | Methotrexate | en_HK |
dc.subject | Neurotoxicity syndromes | en_HK |
dc.subject | Osteosarcoma | en_HK |
dc.title | Diffusion magnetic resonance imaging findings in acute methotrexate neurotoxicity | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Khong, PL:plkhong@hkucc.hku.hk | en_HK |
dc.identifier.authority | Khong, PL=rp00467 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.scopus | eid_2-s2.0-42649095958 | en_HK |
dc.identifier.hkuros | 128336 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-42649095958&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 8 | en_HK |
dc.identifier.issue | 4 | en_HK |
dc.identifier.spage | 250 | en_HK |
dc.identifier.epage | 253 | en_HK |
dc.publisher.place | Hong Kong | en_HK |
dc.identifier.scopusauthorid | Tsang, DSF=36883534900 | en_HK |
dc.identifier.scopusauthorid | Khong, PL=7006693233 | en_HK |
dc.identifier.issnl | 1029-5097 | - |