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Article: Childhood acute disseminated encephalomyelitis: The role of brain and spinal cord MRI

TitleChildhood acute disseminated encephalomyelitis: The role of brain and spinal cord MRI
Authors
KeywordsAcute disseminated encephalomyelitis
Childhood
Clinical outcome
MRI
Issue Date2002
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00247/index.htm
Citation
Pediatric Radiology, 2002, v. 32 n. 1, p. 59-66 How to Cite?
AbstractBackground. It is recognised that the clinical and radiological spectrum of childhood acute disseminated encephalomyelitis (ADEM) is wide. Objective. To determine whether initial MRI features are predictive of clinical outcome and to determine the role of MRI in the management of ADEM. Materials and Methods. The MRI scans of ten consecutive children (eight boys, two girls), clinically and radiologically diagnosed to have ADEM, were retrospectively reviewed. Follow-up MRI was available for eight patients. Results. Lesions ranged from small and punctate (<1 cm) to moderate sized and confluent (4-5 cm) to diffuse and extensive. Spinal cord lesions, seen in five of seven children, were contiguous or segmental. Seven children (70%) made good clinical recovery while three children (30%) remained severely handicapped. There was no correlation between the site, extent and pattern of involvement and clinical outcome. However, the evolution of MRI findings on follow-up correlated well with the subsequent clinical course and outcome. Conclusions. Although the extent and site of lesions on initial MRI scans are not predictive of clinical outcome, early MRI of the brain and spine is useful in aiding clinical diagnosis, and subsequent follow-up MRI is helpful in monitoring disease progression.
Persistent Identifierhttp://hdl.handle.net/10722/72385
ISSN
2015 Impact Factor: 1.525
2015 SCImago Journal Rankings: 0.593
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKhong, PLen_HK
dc.contributor.authorHo, HKen_HK
dc.contributor.authorCheng, PWen_HK
dc.contributor.authorWong, VCNen_HK
dc.contributor.authorGoh, Wen_HK
dc.contributor.authorChan, FLen_HK
dc.date.accessioned2010-09-06T06:41:11Z-
dc.date.available2010-09-06T06:41:11Z-
dc.date.issued2002en_HK
dc.identifier.citationPediatric Radiology, 2002, v. 32 n. 1, p. 59-66en_HK
dc.identifier.issn0301-0449en_HK
dc.identifier.urihttp://hdl.handle.net/10722/72385-
dc.description.abstractBackground. It is recognised that the clinical and radiological spectrum of childhood acute disseminated encephalomyelitis (ADEM) is wide. Objective. To determine whether initial MRI features are predictive of clinical outcome and to determine the role of MRI in the management of ADEM. Materials and Methods. The MRI scans of ten consecutive children (eight boys, two girls), clinically and radiologically diagnosed to have ADEM, were retrospectively reviewed. Follow-up MRI was available for eight patients. Results. Lesions ranged from small and punctate (<1 cm) to moderate sized and confluent (4-5 cm) to diffuse and extensive. Spinal cord lesions, seen in five of seven children, were contiguous or segmental. Seven children (70%) made good clinical recovery while three children (30%) remained severely handicapped. There was no correlation between the site, extent and pattern of involvement and clinical outcome. However, the evolution of MRI findings on follow-up correlated well with the subsequent clinical course and outcome. Conclusions. Although the extent and site of lesions on initial MRI scans are not predictive of clinical outcome, early MRI of the brain and spine is useful in aiding clinical diagnosis, and subsequent follow-up MRI is helpful in monitoring disease progression.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00247/index.htmen_HK
dc.relation.ispartofPediatric Radiologyen_HK
dc.subjectAcute disseminated encephalomyelitisen_HK
dc.subjectChildhooden_HK
dc.subjectClinical outcomeen_HK
dc.subjectMRIen_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshBrain - pathologyen_HK
dc.subject.meshChilden_HK
dc.subject.meshChild, Preschoolen_HK
dc.subject.meshEncephalomyelitis, Acute Disseminated - pathologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInfanten_HK
dc.subject.meshMagnetic Resonance Imagingen_HK
dc.subject.meshMaleen_HK
dc.subject.meshPredictive Value of Testsen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshSpinal Cord - pathologyen_HK
dc.titleChildhood acute disseminated encephalomyelitis: The role of brain and spinal cord MRIen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0301-0449&volume=32&spage=59&epage=66&date=2002&atitle=Childhood+acute+disseminated+encephalomyelitis:+the+role+of+brain+and+spinal+cord+MRIen_HK
dc.identifier.emailKhong, PL:plkhong@hkucc.hku.hken_HK
dc.identifier.emailWong, VCN:vcnwong@hku.hken_HK
dc.identifier.authorityKhong, PL=rp00467en_HK
dc.identifier.authorityWong, VCN=rp00334en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00247-001-0582-6en_HK
dc.identifier.pmid11819066-
dc.identifier.scopuseid_2-s2.0-0036934752en_HK
dc.identifier.hkuros65292en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036934752&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue1en_HK
dc.identifier.spage59en_HK
dc.identifier.epage66en_HK
dc.identifier.isiWOS:000173546000013-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridKhong, PL=7006693233en_HK
dc.identifier.scopusauthoridHo, HK=7401465257en_HK
dc.identifier.scopusauthoridCheng, PW=7401618753en_HK
dc.identifier.scopusauthoridWong, VCN=7202525632en_HK
dc.identifier.scopusauthoridGoh, W=7005651404en_HK
dc.identifier.scopusauthoridChan, FL=7202586444en_HK

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