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Article: Children with respiratory disease associated with metapneumovirus in Hong Kong

TitleChildren with respiratory disease associated with metapneumovirus in Hong Kong
Authors
Issue Date2003
PublisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm
Citation
Emerging Infectious Diseases, 2003, v. 9 n. 6, p. 628-633 How to Cite?
AbstractHuman metapneumovirus (HMPV) is a newly discovered pathogen thought to be associated with respiratory disease. We report the results of a study of 587 children hospitalized with respiratory infection over a 13-month period. HMPV was detected in the nasopharyngeal aspirates from 32 (5.5%) children by reverse transcription-polymerase chain reaction. HMPV infection was associated with clinical diagnoses of pneumonia (36%), asthma exacerbation (23%), or acute bronchiolitis (10%). When compared to those with respiratory syncytial virus infection, children with HMPV infection were older, and wheezing was more likely to represent asthma exacerbation rather than acute bronchiolitis. HMPV viral activity peaked during the spring-summer period in Hong Kong. Phylogenetically, all HMPV virus strains from Hong Kong belonged to one of the two genetic lineages previously described. HMPV contributed to 441.6 hospital admissions per 100,000 population <6 years of age.
Persistent Identifierhttp://hdl.handle.net/10722/72365
ISSN
2015 Impact Factor: 6.994
2015 SCImago Journal Rankings: 3.023
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorTang, WHen_HK
dc.contributor.authorChan, KHen_HK
dc.contributor.authorKhong, PLen_HK
dc.contributor.authorGuan, Yen_HK
dc.contributor.authorLau, YLen_HK
dc.contributor.authorChiu, SSen_HK
dc.date.accessioned2010-09-06T06:40:59Z-
dc.date.available2010-09-06T06:40:59Z-
dc.date.issued2003en_HK
dc.identifier.citationEmerging Infectious Diseases, 2003, v. 9 n. 6, p. 628-633en_HK
dc.identifier.issn1080-6040en_HK
dc.identifier.urihttp://hdl.handle.net/10722/72365-
dc.description.abstractHuman metapneumovirus (HMPV) is a newly discovered pathogen thought to be associated with respiratory disease. We report the results of a study of 587 children hospitalized with respiratory infection over a 13-month period. HMPV was detected in the nasopharyngeal aspirates from 32 (5.5%) children by reverse transcription-polymerase chain reaction. HMPV infection was associated with clinical diagnoses of pneumonia (36%), asthma exacerbation (23%), or acute bronchiolitis (10%). When compared to those with respiratory syncytial virus infection, children with HMPV infection were older, and wheezing was more likely to represent asthma exacerbation rather than acute bronchiolitis. HMPV viral activity peaked during the spring-summer period in Hong Kong. Phylogenetically, all HMPV virus strains from Hong Kong belonged to one of the two genetic lineages previously described. HMPV contributed to 441.6 hospital admissions per 100,000 population <6 years of age.en_HK
dc.languageengen_HK
dc.publisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htmen_HK
dc.relation.ispartofEmerging Infectious Diseasesen_HK
dc.subject.meshChilden_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFever - diagnosisen_HK
dc.subject.meshHong Kong - epidemiologyen_HK
dc.subject.meshHospitalizationen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInfanten_HK
dc.subject.meshInfluenza A virus - isolation & purificationen_HK
dc.subject.meshInfluenza, Human - complications - diagnosis - epidemiologyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMetapneumovirus - isolation & purificationen_HK
dc.subject.meshParamyxoviridae Infections - diagnosis - epidemiology - virologyen_HK
dc.subject.meshPhylogenyen_HK
dc.subject.meshRespiratory Syncytial Virus Infections - diagnosis - epidemiology - virologyen_HK
dc.subject.meshRespiratory Syncytial Viruses - isolation & purificationen_HK
dc.subject.meshRespiratory Tract Infections - diagnosis - epidemiology - virologyen_HK
dc.titleChildren with respiratory disease associated with metapneumovirus in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1080-6040&volume=9&issue=6&spage=628&epage=633&date=2003&atitle=Children+with+Respiratory+Disease+Associated+with+Metapneumovirus+in+Hong+Kongen_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hken_HK
dc.identifier.emailGuan, Y: yguan@hkucc.hku.hken_HK
dc.identifier.emailLau, YL: lauylung@hku.hken_HK
dc.identifier.emailChiu, SS: ssschiu@hku.hken_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.identifier.authorityKhong, PL=rp00467en_HK
dc.identifier.authorityGuan, Y=rp00397en_HK
dc.identifier.authorityLau, YL=rp00361en_HK
dc.identifier.authorityChiu, SS=rp00421en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid12781000-
dc.identifier.pmcidPMC3000155-
dc.identifier.scopuseid_2-s2.0-0037711390en_HK
dc.identifier.hkuros76929en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037711390&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume9en_HK
dc.identifier.issue6en_HK
dc.identifier.spage628en_HK
dc.identifier.epage633en_HK
dc.identifier.isiWOS:000183291900003-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.scopusauthoridTang, WH=7403430888en_HK
dc.identifier.scopusauthoridChan, KH=7406034307en_HK
dc.identifier.scopusauthoridKhong, PL=7006693233en_HK
dc.identifier.scopusauthoridGuan, Y=7202924055en_HK
dc.identifier.scopusauthoridLau, YL=7201403380en_HK
dc.identifier.scopusauthoridChiu, SS=7202291500en_HK

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