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Article: Severe acute respiratory syndrome (SARS): Chest radiographic features in children
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TitleSevere acute respiratory syndrome (SARS): Chest radiographic features in children
 
AuthorsBabyn, PS6
Chu, WCW3
Tsou, IYY4
Wansaicheong, GKL4
Allen, U6
Bitnun, A6
Chee, TSG4
Cheng, FWT3
Chiu, MC2
Fok, TF3
Hon, EKL3
Gahunia, HK6
Kaw, GJL4
Khong, PL1
Leung, CW2
Li, AM3
Manson, D6
Metreweli, C3
Ng, PC3
Read, S6
Stringer, DA5
 
Issue Date2004
 
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00247/index.htm
 
CitationPediatric Radiology, 2004, v. 34 n. 1, p. 47-58 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s00247-003-1081-8
 
AbstractBackground: Severe acute respiratory syndrome (SARS) is a recently recognized condition of viral origin associated with substantial morbidity and mortality rates in adults. Little information is available on its radiologic manifestations in children. Objective: The goal of this study was to characterize the radiographic presentation of children with SARS. Materials and methods: We abstracted data (n = 62) on the radiologic appearance and course of SARS in pediatric patients with suspect (n = 25) or probable (n = 37) SARS, diagnosed in five hospital sites located in three cities: Toronto, Singapore, and Hong Kong. Available chest radiographs and thoracic CTs were reviewed for the presence of the following radiographic findings: airspace disease, air bronchograms, airways inflammation and peribronchial thickening, interstitial disease, pleural effusion, and hilar adenopathy. Results: A total of 62 patients (suspect = 25, probable = 37) were evaluated for SARS. Patient ages ranged from 5.5 months to 17 years and 11.5 months (average, 6 years and 10 months) with a female-to-male ratio of 32:30. Forty-one patients (66.1%) were in close contact with other probable, suspect, or quarantined cases; 10 patients (16.1%) had recently traveled to WHO-designated affected areas within 10 days; and 7 patients (11.2%) were transferred from other hospitals that had SARS patients. Three patients, who did not have close/hospital contact or travel history to affected areas, were classified as SARS cases based on their clinical signs and symptoms and on the fact that they were living in an endemic area. The most prominent clinical presentations were fever, with a temperature over 38 °C (100%), cough (62.9%), rhinorrhea (22.6%), myalgia (17.7%), chills (14.5%), and headache (11.3%). Other findings included sore throat (9.7%), gastro-intestinal symptoms (9.7%), rigor (8.1%), and lethargy (6.5%). In general, fever and cough were the most common clinical presentations amongst younger pediatric SARS cases (age < 10 years), whereas, in addition to these symptoms, headache, myalgia, sore throat, chills, and/or rigor were common in older patients (age≥10 years). The chest radiographs of 35.5% of patients were normal. The most prominent radiological findings that were observed in the remaining patients were areas of consolidation (45.2%), often peripheral with multifocal lesions in 22.6%. Peribronchial thickening was noted on chest radiographs of 14.5% of patients. Pleural effusion was observed only in one patient (age 17 years and 11.5 months), whereas interstitial disease was not observed in any patient. Conclusion: In pediatric cases, SARS manifests with nonspecific radiographic features making radiological differentiation difficult, especially from other commonly encountered childhood respiratory viral illnesses causing airspace disease. The radiographic presentation of suspected SARS cases ranged from normal to mild perihilar peribronchial thickening. The radiographic presentations, as expected, were relatively more pronounced in the SARS probable cases.
 
ISSN0301-0449
2012 Impact Factor: 1.565
2012 SCImago Journal Rankings: 0.605
 
DOIhttp://dx.doi.org/10.1007/s00247-003-1081-8
 
ISI Accession Number IDWOS:000188114000008
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorBabyn, PS
 
dc.contributor.authorChu, WCW
 
dc.contributor.authorTsou, IYY
 
dc.contributor.authorWansaicheong, GKL
 
dc.contributor.authorAllen, U
 
dc.contributor.authorBitnun, A
 
dc.contributor.authorChee, TSG
 
dc.contributor.authorCheng, FWT
 
dc.contributor.authorChiu, MC
 
dc.contributor.authorFok, TF
 
dc.contributor.authorHon, EKL
 
dc.contributor.authorGahunia, HK
 
dc.contributor.authorKaw, GJL
 
dc.contributor.authorKhong, PL
 
dc.contributor.authorLeung, CW
 
dc.contributor.authorLi, AM
 
dc.contributor.authorManson, D
 
dc.contributor.authorMetreweli, C
 
dc.contributor.authorNg, PC
 
dc.contributor.authorRead, S
 
dc.contributor.authorStringer, DA
 
dc.date.accessioned2010-09-06T06:40:53Z
 
dc.date.available2010-09-06T06:40:53Z
 
dc.date.issued2004
 
dc.description.abstractBackground: Severe acute respiratory syndrome (SARS) is a recently recognized condition of viral origin associated with substantial morbidity and mortality rates in adults. Little information is available on its radiologic manifestations in children. Objective: The goal of this study was to characterize the radiographic presentation of children with SARS. Materials and methods: We abstracted data (n = 62) on the radiologic appearance and course of SARS in pediatric patients with suspect (n = 25) or probable (n = 37) SARS, diagnosed in five hospital sites located in three cities: Toronto, Singapore, and Hong Kong. Available chest radiographs and thoracic CTs were reviewed for the presence of the following radiographic findings: airspace disease, air bronchograms, airways inflammation and peribronchial thickening, interstitial disease, pleural effusion, and hilar adenopathy. Results: A total of 62 patients (suspect = 25, probable = 37) were evaluated for SARS. Patient ages ranged from 5.5 months to 17 years and 11.5 months (average, 6 years and 10 months) with a female-to-male ratio of 32:30. Forty-one patients (66.1%) were in close contact with other probable, suspect, or quarantined cases; 10 patients (16.1%) had recently traveled to WHO-designated affected areas within 10 days; and 7 patients (11.2%) were transferred from other hospitals that had SARS patients. Three patients, who did not have close/hospital contact or travel history to affected areas, were classified as SARS cases based on their clinical signs and symptoms and on the fact that they were living in an endemic area. The most prominent clinical presentations were fever, with a temperature over 38 °C (100%), cough (62.9%), rhinorrhea (22.6%), myalgia (17.7%), chills (14.5%), and headache (11.3%). Other findings included sore throat (9.7%), gastro-intestinal symptoms (9.7%), rigor (8.1%), and lethargy (6.5%). In general, fever and cough were the most common clinical presentations amongst younger pediatric SARS cases (age < 10 years), whereas, in addition to these symptoms, headache, myalgia, sore throat, chills, and/or rigor were common in older patients (age≥10 years). The chest radiographs of 35.5% of patients were normal. The most prominent radiological findings that were observed in the remaining patients were areas of consolidation (45.2%), often peripheral with multifocal lesions in 22.6%. Peribronchial thickening was noted on chest radiographs of 14.5% of patients. Pleural effusion was observed only in one patient (age 17 years and 11.5 months), whereas interstitial disease was not observed in any patient. Conclusion: In pediatric cases, SARS manifests with nonspecific radiographic features making radiological differentiation difficult, especially from other commonly encountered childhood respiratory viral illnesses causing airspace disease. The radiographic presentation of suspected SARS cases ranged from normal to mild perihilar peribronchial thickening. The radiographic presentations, as expected, were relatively more pronounced in the SARS probable cases.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationPediatric Radiology, 2004, v. 34 n. 1, p. 47-58 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s00247-003-1081-8
 
dc.identifier.doihttp://dx.doi.org/10.1007/s00247-003-1081-8
 
dc.identifier.epage58
 
dc.identifier.hkuros87695
 
dc.identifier.isiWOS:000188114000008
 
dc.identifier.issn0301-0449
2012 Impact Factor: 1.565
2012 SCImago Journal Rankings: 0.605
 
dc.identifier.issue1
 
dc.identifier.openurl
 
dc.identifier.pmid14624321
 
dc.identifier.scopuseid_2-s2.0-9144253865
 
dc.identifier.spage47
 
dc.identifier.urihttp://hdl.handle.net/10722/72357
 
dc.identifier.volume34
 
dc.languageeng
 
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00247/index.htm
 
dc.publisher.placeGermany
 
dc.relation.ispartofPediatric Radiology
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAdolescent
 
dc.subject.meshChild
 
dc.subject.meshChild, Preschool
 
dc.subject.meshFemale
 
dc.subject.meshHumans
 
dc.subject.meshInfant
 
dc.subject.meshMale
 
dc.subject.meshRadiography, Thoracic
 
dc.subject.meshSevere Acute Respiratory Syndrome - diagnosis - radiography - transmission
 
dc.subject.meshTomography, X-Ray Computed
 
dc.titleSevere acute respiratory syndrome (SARS): Chest radiographic features in children
 
dc.typeArticle
 
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<contributor.author>Tsou, IYY</contributor.author>
<contributor.author>Wansaicheong, GKL</contributor.author>
<contributor.author>Allen, U</contributor.author>
<contributor.author>Bitnun, A</contributor.author>
<contributor.author>Chee, TSG</contributor.author>
<contributor.author>Cheng, FWT</contributor.author>
<contributor.author>Chiu, MC</contributor.author>
<contributor.author>Fok, TF</contributor.author>
<contributor.author>Hon, EKL</contributor.author>
<contributor.author>Gahunia, HK</contributor.author>
<contributor.author>Kaw, GJL</contributor.author>
<contributor.author>Khong, PL</contributor.author>
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<description.abstract>Background: Severe acute respiratory syndrome (SARS) is a recently recognized condition of viral origin associated with substantial morbidity and mortality rates in adults. Little information is available on its radiologic manifestations in children. Objective: The goal of this study was to characterize the radiographic presentation of children with SARS. Materials and methods: We abstracted data (n = 62) on the radiologic appearance and course of SARS in pediatric patients with suspect (n = 25) or probable (n = 37) SARS, diagnosed in five hospital sites located in three cities: Toronto, Singapore, and Hong Kong. Available chest radiographs and thoracic CTs were reviewed for the presence of the following radiographic findings: airspace disease, air bronchograms, airways inflammation and peribronchial thickening, interstitial disease, pleural effusion, and hilar adenopathy. Results: A total of 62 patients (suspect = 25, probable = 37) were evaluated for SARS. Patient ages ranged from 5.5 months to 17 years and 11.5 months (average, 6 years and 10 months) with a female-to-male ratio of 32:30. Forty-one patients (66.1%) were in close contact with other probable, suspect, or quarantined cases; 10 patients (16.1%) had recently traveled to WHO-designated affected areas within 10 days; and 7 patients (11.2%) were transferred from other hospitals that had SARS patients. Three patients, who did not have close/hospital contact or travel history to affected areas, were classified as SARS cases based on their clinical signs and symptoms and on the fact that they were living in an endemic area. The most prominent clinical presentations were fever, with a temperature over 38 &#176;C (100%), cough (62.9%), rhinorrhea (22.6%), myalgia (17.7%), chills (14.5%), and headache (11.3%). Other findings included sore throat (9.7%), gastro-intestinal symptoms (9.7%), rigor (8.1%), and lethargy (6.5%). In general, fever and cough were the most common clinical presentations amongst younger pediatric SARS cases (age &lt; 10 years), whereas, in addition to these symptoms, headache, myalgia, sore throat, chills, and/or rigor were common in older patients (age&#8805;10 years). The chest radiographs of 35.5% of patients were normal. The most prominent radiological findings that were observed in the remaining patients were areas of consolidation (45.2%), often peripheral with multifocal lesions in 22.6%. Peribronchial thickening was noted on chest radiographs of 14.5% of patients. Pleural effusion was observed only in one patient (age 17 years and 11.5 months), whereas interstitial disease was not observed in any patient. Conclusion: In pediatric cases, SARS manifests with nonspecific radiographic features making radiological differentiation difficult, especially from other commonly encountered childhood respiratory viral illnesses causing airspace disease. The radiographic presentation of suspected SARS cases ranged from normal to mild perihilar peribronchial thickening. The radiographic presentations, as expected, were relatively more pronounced in the SARS probable cases.</description.abstract>
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Author Affiliations
  1. The University of Hong Kong
  2. Princess Margaret Hospital Hong Kong
  3. Prince of Wales Hospital Hong Kong
  4. Tan Tock Seng Hospital
  5. National University Hospital, Singapore
  6. Hospital for Sick Children University of Toronto