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Article: Current management strategy of nasopharyngeal carcinoma

TitleCurrent management strategy of nasopharyngeal carcinoma
Authors
KeywordsChemotherapy
Diagnosis
Management
Nasopharyngeal carcinoma
Radiotherapy
Surgical salvage
Issue Date2010
PublisherKorean Society of Otorhinolaryngology-Head and Neck Surgery. The Journal's web site is located at http://e-ceo.org/
Citation
Clinical And Experimental Otorhinolaryngology, 2010, v. 3 n. 1, p. 1-12 How to Cite?
AbstractNasopharyngeal carcinoma is an unique head and neck cancer. It is common among the southern Chinese and is closely associated with the Epstein Barr virus (EBV). To diagnose the disease in its early stage is infrequent as the symptoms are usually trivial and patients only present in late stages. Testing the blood for elevated EBV DNA has now become a screening test for the high risk group of patients, aiming to diagnose the disease in its early stages. Imaging studies, positron emission tomography scans in addition to clinical examination provide information on the extent of the disease. The confirmation of the disease still depends on endoscopic examination and biopsy. Radiotherapy with or without chemotherapy has been the primary treatment modality. The application of intensity modulated radiotherapy and the use of concomitant chemoradiation have improved the control of nasopharyngeal carcinoma together with the reduction of long term side effects. The early detection of residual or recurrence tumor in the neck or at the primary site has allowed delivery of salvage treatment. The choice of the optimal surgical salvage, either for neck disease or primary tumor depends on the extent of the residual or recurrent disease. The outcome of these patients have improved with the application of the appropriate surgical salvage. © 2010 by Korean Society of Otorhinolaryngology-Head and Neck Surgery.
Persistent Identifierhttp://hdl.handle.net/10722/72025
ISSN
2015 Impact Factor: 0.855
2015 SCImago Journal Rankings: 0.530
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWei, WIen_HK
dc.contributor.authorKwong, DLWen_HK
dc.date.accessioned2010-09-06T06:37:36Z-
dc.date.available2010-09-06T06:37:36Z-
dc.date.issued2010en_HK
dc.identifier.citationClinical And Experimental Otorhinolaryngology, 2010, v. 3 n. 1, p. 1-12en_HK
dc.identifier.issn1976-8710en_HK
dc.identifier.urihttp://hdl.handle.net/10722/72025-
dc.description.abstractNasopharyngeal carcinoma is an unique head and neck cancer. It is common among the southern Chinese and is closely associated with the Epstein Barr virus (EBV). To diagnose the disease in its early stage is infrequent as the symptoms are usually trivial and patients only present in late stages. Testing the blood for elevated EBV DNA has now become a screening test for the high risk group of patients, aiming to diagnose the disease in its early stages. Imaging studies, positron emission tomography scans in addition to clinical examination provide information on the extent of the disease. The confirmation of the disease still depends on endoscopic examination and biopsy. Radiotherapy with or without chemotherapy has been the primary treatment modality. The application of intensity modulated radiotherapy and the use of concomitant chemoradiation have improved the control of nasopharyngeal carcinoma together with the reduction of long term side effects. The early detection of residual or recurrence tumor in the neck or at the primary site has allowed delivery of salvage treatment. The choice of the optimal surgical salvage, either for neck disease or primary tumor depends on the extent of the residual or recurrent disease. The outcome of these patients have improved with the application of the appropriate surgical salvage. © 2010 by Korean Society of Otorhinolaryngology-Head and Neck Surgery.en_HK
dc.languageengen_HK
dc.publisherKorean Society of Otorhinolaryngology-Head and Neck Surgery. The Journal's web site is located at http://e-ceo.org/en_HK
dc.relation.ispartofClinical and Experimental Otorhinolaryngologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectChemotherapyen_HK
dc.subjectDiagnosisen_HK
dc.subjectManagementen_HK
dc.subjectNasopharyngeal carcinomaen_HK
dc.subjectRadiotherapyen_HK
dc.subjectSurgical salvageen_HK
dc.titleCurrent management strategy of nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1976-8710&volume=3&spage=1&epage=12&date=2010&atitle=Current+management+strategy+of+nasopharyngeal+carcinomaen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityKwong, DLW=rp00414en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.3342/ceo.2010.3.1.1en_HK
dc.identifier.scopuseid_2-s2.0-77952051713en_HK
dc.identifier.hkuros169988en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77952051713&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume3en_HK
dc.identifier.issue1en_HK
dc.identifier.spage1en_HK
dc.identifier.epage12en_HK
dc.identifier.isiWOS:000276545700001-
dc.publisher.placeSeoulen_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridKwong, DLW=15744231600en_HK

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