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Article: Randomized evaluation of the audiologic outcome of ventilation tube insertion for middle ear effusion in patients with nasopharyngeal carcinoma

TitleRandomized evaluation of the audiologic outcome of ventilation tube insertion for middle ear effusion in patients with nasopharyngeal carcinoma
Authors
KeywordsEffusion
Grommet
Hearing
Nasopharynx
Radiotherapy
Randomized
Issue Date2002
PublisherBC Decker Inc. The Journal's web site is located at http://www.bcdecker.com/productDetails.aspx?BJID=10
Citation
Journal Of Otolaryngology, 2002, v. 31 n. 5, p. 287-293 How to Cite?
AbstractObjective: Complications after ventilation tube insertion for middle ear effusion in patients with nasopharyngeal carcinoma are frequent. This may compromise the overall benefit obtained from the procedure. This study evaluates the hearing improvement after tube insertion compared with observation alone to see if the benefits of the procedure outweigh its potential complications. Design: Prospective randomized controlled trial. Setting: Full clinical and emergency otolaryngologic services hospital in an academic institution. Methods: Patients with nasopharyngeal carcinoma and middle ear effusion were randomized for preradiotherapy ventilation tube insertion or observation. Audiologic assessment with a pure-tone audiogram was performed before the procedure, after ventilation tube insertion, and at fixed intervals after irradiation. Audiologic outcome was compared between the two groups. Main Outcome Measure: Air-conduction threshold and air-bone gap on a pure-tone audiogram at different intervals after radiotherapy. Results: There was no significant difference in hearing threshold changes between the two groups for up to 4 years. Both groups had air-bone gap improvement following radiotherapy and the improvement was not significantly different between the two groups. The proportion of patients with closure of the air-bone gap on follow-up was not different between the two groups. Conclusions: Ventilation tube insertion before radiotherapy did not offer additional hearing benefit when compared with observation alone. The procedure had no deleterious effect on hearing for up to 4 years.
Persistent Identifierhttp://hdl.handle.net/10722/71938
ISSN
2007 Impact Factor: 0.497
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHo, WKen_HK
dc.contributor.authorWei, WIen_HK
dc.contributor.authorKwong, DLWen_HK
dc.contributor.authorSham, JSTen_HK
dc.contributor.authorAu, DKKen_HK
dc.contributor.authorChua, DTTen_HK
dc.contributor.authorChoy, DTKen_HK
dc.date.accessioned2010-09-06T06:36:41Z-
dc.date.available2010-09-06T06:36:41Z-
dc.date.issued2002en_HK
dc.identifier.citationJournal Of Otolaryngology, 2002, v. 31 n. 5, p. 287-293en_HK
dc.identifier.issn0381-6605en_HK
dc.identifier.urihttp://hdl.handle.net/10722/71938-
dc.description.abstractObjective: Complications after ventilation tube insertion for middle ear effusion in patients with nasopharyngeal carcinoma are frequent. This may compromise the overall benefit obtained from the procedure. This study evaluates the hearing improvement after tube insertion compared with observation alone to see if the benefits of the procedure outweigh its potential complications. Design: Prospective randomized controlled trial. Setting: Full clinical and emergency otolaryngologic services hospital in an academic institution. Methods: Patients with nasopharyngeal carcinoma and middle ear effusion were randomized for preradiotherapy ventilation tube insertion or observation. Audiologic assessment with a pure-tone audiogram was performed before the procedure, after ventilation tube insertion, and at fixed intervals after irradiation. Audiologic outcome was compared between the two groups. Main Outcome Measure: Air-conduction threshold and air-bone gap on a pure-tone audiogram at different intervals after radiotherapy. Results: There was no significant difference in hearing threshold changes between the two groups for up to 4 years. Both groups had air-bone gap improvement following radiotherapy and the improvement was not significantly different between the two groups. The proportion of patients with closure of the air-bone gap on follow-up was not different between the two groups. Conclusions: Ventilation tube insertion before radiotherapy did not offer additional hearing benefit when compared with observation alone. The procedure had no deleterious effect on hearing for up to 4 years.en_HK
dc.languageengen_HK
dc.publisherBC Decker Inc. The Journal's web site is located at http://www.bcdecker.com/productDetails.aspx?BJID=10en_HK
dc.relation.ispartofJournal of Otolaryngologyen_HK
dc.subjectEffusionen_HK
dc.subjectGrommeten_HK
dc.subjectHearingen_HK
dc.subjectNasopharynxen_HK
dc.subjectRadiotherapyen_HK
dc.subjectRandomizeden_HK
dc.subject.meshAdulten_HK
dc.subject.meshAudiometry, Pure-Tone - methodsen_HK
dc.subject.meshCarcinoma, Squamous Cell - complications - pathology - radiotherapyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHearing Loss, Conductive - diagnosis - epidemiology - etiologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMiddle Ear Ventilation - methodsen_HK
dc.subject.meshNasopharyngeal Neoplasms - complications - pathology - radiotherapyen_HK
dc.subject.meshOtitis Media with Effusion - complications - surgeryen_HK
dc.subject.meshRadiation Dosageen_HK
dc.subject.meshSeverity of Illness Indexen_HK
dc.titleRandomized evaluation of the audiologic outcome of ventilation tube insertion for middle ear effusion in patients with nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0381-6605&volume=31&issue=5&spage=287&epage=293&date=2002&atitle=Randomized+evaluation+of+the+audiologic+outcome+of+ventilation+tube+insertion+for+middle+ear+effusion+in+patients+with+nasopharyngeal+carcinomaen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_HK
dc.identifier.emailAu, DKK: kinkwau@hkucc.hku.hken_HK
dc.identifier.emailChua, DTT: dttchua@hkucc.hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityKwong, DLW=rp00414en_HK
dc.identifier.authorityAu, DKK=rp00385en_HK
dc.identifier.authorityChua, DTT=rp00415en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid12512893-
dc.identifier.scopuseid_2-s2.0-0036820695en_HK
dc.identifier.hkuros75777en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036820695&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume31en_HK
dc.identifier.issue5en_HK
dc.identifier.spage287en_HK
dc.identifier.epage293en_HK
dc.identifier.isiWOS:000180382600005-
dc.publisher.placeCanadaen_HK
dc.identifier.scopusauthoridHo, WK=7402968844en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridKwong, DLW=15744231600en_HK
dc.identifier.scopusauthoridSham, JST=24472255400en_HK
dc.identifier.scopusauthoridAu, DKK=7004909224en_HK
dc.identifier.scopusauthoridChua, DTT=7006773480en_HK
dc.identifier.scopusauthoridChoy, DTK=7102939127en_HK

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