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Article: Elevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma

TitleElevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma
Authors
Wong, TSKwong, DLWSham, JWei, WIKwong, YLYuen, APW
KeywordsHead and neck cancers
Lymph node metastasis
Nasopharyngeal carcinoma
Osteopontin
Plasma
Issue Date2005
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejso
Citation
European Journal Of Surgical Oncology, 2005, v. 31 n. 5, p. 555-558 How to Cite?
DOI: http://dx.doi.org/10.1016/j.ejso.2005.01.005
AbstractAims. We evaluated the clinicopathologic relevance of plasma osteopontin (OPN) level in nasopharyngeal carcinoma patients. Methods. Seventy-two plasma samples were collected from patients with undifferentiated nasopharyngeal carcinoma (NPC) before radiotherapy. Plasma OPN level was determined by quantitative sandwich enzyme immunoassay. The plasma OPN level was evaluated for its clinicopathologic relevance. Results. The mean plasma OPN level was significantly higher in NPC patients than in normal controls (184.66 vs 75.89 ng/ml, p<0.001). In addition, high OPN level was found in the patients with advanced cancer and was correlated with neck node metastasis (p<0.05). Conclusions: Our findings indicated a potential role of OPN in the pathogenesis and nodal metastasis of undifferentiated NPC. © 2005 Published by Elsevier Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/71907
ISSN
0748-7983
2023 Impact Factor: 3.5
2023 SCImago Journal Rankings: 1.164
ISI Accession Number ID
WOS:000229894500018
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorWong, TSen_HK
dc.contributor.authorKwong, DLWen_HK
dc.contributor.authorSham, Jen_HK
dc.contributor.authorWei, WIen_HK
dc.contributor.authorKwong, YLen_HK
dc.contributor.authorYuen, APWen_HK
dc.date.accessioned2010-09-06T06:36:21Z-
dc.date.available2010-09-06T06:36:21Z-
dc.date.issued2005en_HK
dc.identifier.citationEuropean Journal Of Surgical Oncology, 2005, v. 31 n. 5, p. 555-558en_HK
dc.identifier.issn0748-7983en_HK
dc.identifier.urihttp://hdl.handle.net/10722/71907-
dc.description.abstractAims. We evaluated the clinicopathologic relevance of plasma osteopontin (OPN) level in nasopharyngeal carcinoma patients. Methods. Seventy-two plasma samples were collected from patients with undifferentiated nasopharyngeal carcinoma (NPC) before radiotherapy. Plasma OPN level was determined by quantitative sandwich enzyme immunoassay. The plasma OPN level was evaluated for its clinicopathologic relevance. Results. The mean plasma OPN level was significantly higher in NPC patients than in normal controls (184.66 vs 75.89 ng/ml, p<0.001). In addition, high OPN level was found in the patients with advanced cancer and was correlated with neck node metastasis (p<0.05). Conclusions: Our findings indicated a potential role of OPN in the pathogenesis and nodal metastasis of undifferentiated NPC. © 2005 Published by Elsevier Ltd.en_HK
dc.languageengen_HK
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejsoen_HK
dc.relation.ispartofEuropean Journal of Surgical Oncologyen_HK
dc.subjectHead and neck cancersen_HK
dc.subjectLymph node metastasisen_HK
dc.subjectNasopharyngeal carcinomaen_HK
dc.subjectOsteopontinen_HK
dc.subjectPlasmaen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNasopharyngeal Neoplasms - blood - pathologyen_HK
dc.subject.meshNeoplasm Stagingen_HK
dc.subject.meshOsteopontinen_HK
dc.subject.meshSialoglycoproteins - blooden_HK
dc.subject.meshTumor Markers, Biological - blooden_HK
dc.titleElevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0748-7983&volume=31&spage=555&epage=558&date=2005&atitle=Elevation+of+plasma+osteopontin+level+in+patients+with+undifferentiated+nasopharyngeal+carcinomaen_HK
dc.identifier.emailWong, TS: thiansze@graduate.hku.hken_HK
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailKwong, YL: ylkwong@hku.hken_HK
dc.identifier.authorityWong, TS=rp00478en_HK
dc.identifier.authorityKwong, DLW=rp00414en_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ejso.2005.01.005en_HK
dc.identifier.pmid15922893-
dc.identifier.scopuseid_2-s2.0-19444384643en_HK
dc.identifier.hkuros98950en_HK
dc.identifier.hkuros116869-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-19444384643&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume31en_HK
dc.identifier.issue5en_HK
dc.identifier.spage555en_HK
dc.identifier.epage558en_HK
dc.identifier.isiWOS:000229894500018-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, TS=7403531328en_HK
dc.identifier.scopusauthoridKwong, DLW=15744231600en_HK
dc.identifier.scopusauthoridSham, J=24472255400en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK
dc.identifier.scopusauthoridYuen, APW=7006290111en_HK
dc.identifier.issnl0748-7983-

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