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- Publisher Website: 10.1016/S0165-6147(02)01989-2
- Scopus: eid_2-s2.0-0036570288
- PMID: 12007993
- WOS: WOS:000175361400005
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Article: The role of the transferrin-transferrin-receptor system in drug delivery and targeting
Title | The role of the transferrin-transferrin-receptor system in drug delivery and targeting |
---|---|
Authors | |
Issue Date | 2002 |
Publisher | Elsevier Ltd, Trends Journals. The Journal's web site is located at http://www.elsevier.com/locate/tips |
Citation | Trends In Pharmacological Sciences, 2002, v. 23 n. 5, p. 206-209 How to Cite? |
Abstract | Exploration of the potential of site-specific and target-oriented drug delivery systems has gained interest recently. Indeed, the efficient cellular mechanism of transferrin uptake has been exploited for the delivery not only of anticancer drugs and proteins, but also of therapeutic genes into proliferating malignant cells that overexpress transferrin receptors. In particular, the transferrin receptor offers great promise in the delivery of therapeutic agents across the blood-brain barrier to the brain. |
Persistent Identifier | http://hdl.handle.net/10722/70468 |
ISSN | 2023 Impact Factor: 13.9 2023 SCImago Journal Rankings: 3.232 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Li, H | en_HK |
dc.contributor.author | Sun, H | en_HK |
dc.contributor.author | Qian, ZM | en_HK |
dc.date.accessioned | 2010-09-06T06:23:10Z | - |
dc.date.available | 2010-09-06T06:23:10Z | - |
dc.date.issued | 2002 | en_HK |
dc.identifier.citation | Trends In Pharmacological Sciences, 2002, v. 23 n. 5, p. 206-209 | en_HK |
dc.identifier.issn | 0165-6147 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/70468 | - |
dc.description.abstract | Exploration of the potential of site-specific and target-oriented drug delivery systems has gained interest recently. Indeed, the efficient cellular mechanism of transferrin uptake has been exploited for the delivery not only of anticancer drugs and proteins, but also of therapeutic genes into proliferating malignant cells that overexpress transferrin receptors. In particular, the transferrin receptor offers great promise in the delivery of therapeutic agents across the blood-brain barrier to the brain. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Elsevier Ltd, Trends Journals. The Journal's web site is located at http://www.elsevier.com/locate/tips | en_HK |
dc.relation.ispartof | Trends in Pharmacological Sciences | en_HK |
dc.rights | Trends in Pharmacological Sciences. Copyright © Elsevier Ltd, Trends Journals. | en_HK |
dc.title | The role of the transferrin-transferrin-receptor system in drug delivery and targeting | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0165-6147&volume=23&spage=206&epage=209&date=2002&atitle=The+role+of+the+transferrin-transferrin-receptor+system+in+drug+delivery+and+targeting | en_HK |
dc.identifier.email | Sun, H:hsun@hkucc.hku.hk | en_HK |
dc.identifier.authority | Sun, H=rp00777 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/S0165-6147(02)01989-2 | en_HK |
dc.identifier.pmid | 12007993 | - |
dc.identifier.scopus | eid_2-s2.0-0036570288 | en_HK |
dc.identifier.hkuros | 72315 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0036570288&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 23 | en_HK |
dc.identifier.issue | 5 | en_HK |
dc.identifier.spage | 206 | en_HK |
dc.identifier.epage | 209 | en_HK |
dc.identifier.isi | WOS:000175361400005 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Li, H=14023043100 | en_HK |
dc.identifier.scopusauthorid | Sun, H=7404827446 | en_HK |
dc.identifier.scopusauthorid | Qian, ZM=7201384672 | en_HK |
dc.identifier.issnl | 0165-6147 | - |