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Article: Subcellular localization of a fluorescent artemisinin derivative to endoplasmic reticulum

TitleSubcellular localization of a fluorescent artemisinin derivative to endoplasmic reticulum
Authors
Issue Date2010
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.html
Citation
Organic Letters, 2010, v. 12 n. 7, p. 1420-1423 How to Cite?
Abstract"Chemical eqation presented" A cytotoxic artemisinin derivative conjugated with a fluorescent dansyl moiety was synthesized and Its subcellular localization In Hep3B cells was examined. Comparison of the localization signals of the fluorescent artemisinin derivative with organelle specific dyes revealed that endoplasmic reticulum (ER) Is the main site of its accumulation. © 2010 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/70343
ISSN
2015 Impact Factor: 6.732
2015 SCImago Journal Rankings: 3.187
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong
Hong Kong Polytechnic University
Funding Information:

We are thankful for the financial support of The University of Hong Kong and Hong Kong Polytechnic University.

References

 

DC FieldValueLanguage
dc.contributor.authorLiu, Yen_HK
dc.contributor.authorLok, CNen_HK
dc.contributor.authorKo, BCBen_HK
dc.contributor.authorShum, TYTen_HK
dc.contributor.authorWong, MKen_HK
dc.contributor.authorChe, CMen_HK
dc.date.accessioned2010-09-06T06:21:59Z-
dc.date.available2010-09-06T06:21:59Z-
dc.date.issued2010en_HK
dc.identifier.citationOrganic Letters, 2010, v. 12 n. 7, p. 1420-1423en_HK
dc.identifier.issn1523-7060en_HK
dc.identifier.urihttp://hdl.handle.net/10722/70343-
dc.description.abstract"Chemical eqation presented" A cytotoxic artemisinin derivative conjugated with a fluorescent dansyl moiety was synthesized and Its subcellular localization In Hep3B cells was examined. Comparison of the localization signals of the fluorescent artemisinin derivative with organelle specific dyes revealed that endoplasmic reticulum (ER) Is the main site of its accumulation. © 2010 American Chemical Society.en_HK
dc.languageengen_HK
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.htmlen_HK
dc.relation.ispartofOrganic Lettersen_HK
dc.titleSubcellular localization of a fluorescent artemisinin derivative to endoplasmic reticulumen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1523-7060&volume=12&spage=1420&epage=1423&date=2010&atitle=Subcellular+Localization+of+a+Fluorescent+Artemisinin+Derivative+to+Endoplasmic+Reticulumen_HK
dc.identifier.emailLiu, Y:lyg100@hku.hken_HK
dc.identifier.emailLok, CN:cnlok@hku.hken_HK
dc.identifier.emailChe, CM:cmche@hku.hken_HK
dc.identifier.authorityLiu, Y=rp00749en_HK
dc.identifier.authorityLok, CN=rp00752en_HK
dc.identifier.authorityChe, CM=rp00670en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/ol902890jen_HK
dc.identifier.pmid20192248-
dc.identifier.scopuseid_2-s2.0-77950201383en_HK
dc.identifier.hkuros170077en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77950201383&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume12en_HK
dc.identifier.issue7en_HK
dc.identifier.spage1420en_HK
dc.identifier.epage1423en_HK
dc.identifier.isiWOS:000275885400012-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLiu, Y=8225912600en_HK
dc.identifier.scopusauthoridLok, CN=7006410829en_HK
dc.identifier.scopusauthoridKo, BCB=7102833927en_HK
dc.identifier.scopusauthoridShum, TYT=8922482200en_HK
dc.identifier.scopusauthoridWong, MK=7403908449en_HK
dc.identifier.scopusauthoridChe, CM=7102442791en_HK

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