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Article: Prevalence of neural tube defects in economically and socially deprived area of China

TitlePrevalence of neural tube defects in economically and socially deprived area of China
Authors
KeywordsBirth defects
Folic acid
Neural tube defects
Prevalence
Issue Date2007
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00381/index.htm
Citation
Child's Nervous System, 2007, v. 23 n. 10, p. 1119-1124 How to Cite?
AbstractObjective: This paper aims to understand the situation and epidemiology trend of neural tube defects in Guizhou province, China from 1996 to 2004. Study design: Pregnant women from 17 hospitals in Guizhou province were chosen for investigation of perinatal infants from January 1996 to December 2004. Results: Of 1,208 birth defect cases studied in this 9-year period, a total of 122 cases were identified as neural tube defects (NTD), making up a 10.10% of the total birth defects. The average prevalence rate of NTD was 12.21 per 10,000 births; however, there is no significant difference between the genders. In this study, the age of mothers during pregnancy was shown to be one of the major factors affecting the prevalence rate of NTD and the differences between infants with or without NTD and the usage of folic acid as a supplement during pregnancy were found to be statistical significant. Conclusion: NTD was found to be the most common and serious form of human birth defect in Guizhou province. For prevention, folic acid supplement is thought to be efficacious in inhibiting NTD, and thus, it is essential for people in socially deprived areas to effectively reduce the prevalence of NTD in China. © Springer-Verlag 2007.
Persistent Identifierhttp://hdl.handle.net/10722/70319
ISSN
2015 Impact Factor: 1.08
2015 SCImago Journal Rankings: 0.444
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLiu, Jen_HK
dc.contributor.authorYang, GZen_HK
dc.contributor.authorZhou, JLen_HK
dc.contributor.authorCao, SPen_HK
dc.contributor.authorChau, DHWen_HK
dc.contributor.authorKung, HFen_HK
dc.contributor.authorLin, MCen_HK
dc.date.accessioned2010-09-06T06:21:45Z-
dc.date.available2010-09-06T06:21:45Z-
dc.date.issued2007en_HK
dc.identifier.citationChild's Nervous System, 2007, v. 23 n. 10, p. 1119-1124en_HK
dc.identifier.issn0256-7040en_HK
dc.identifier.urihttp://hdl.handle.net/10722/70319-
dc.description.abstractObjective: This paper aims to understand the situation and epidemiology trend of neural tube defects in Guizhou province, China from 1996 to 2004. Study design: Pregnant women from 17 hospitals in Guizhou province were chosen for investigation of perinatal infants from January 1996 to December 2004. Results: Of 1,208 birth defect cases studied in this 9-year period, a total of 122 cases were identified as neural tube defects (NTD), making up a 10.10% of the total birth defects. The average prevalence rate of NTD was 12.21 per 10,000 births; however, there is no significant difference between the genders. In this study, the age of mothers during pregnancy was shown to be one of the major factors affecting the prevalence rate of NTD and the differences between infants with or without NTD and the usage of folic acid as a supplement during pregnancy were found to be statistical significant. Conclusion: NTD was found to be the most common and serious form of human birth defect in Guizhou province. For prevention, folic acid supplement is thought to be efficacious in inhibiting NTD, and thus, it is essential for people in socially deprived areas to effectively reduce the prevalence of NTD in China. © Springer-Verlag 2007.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00381/index.htmen_HK
dc.relation.ispartofChild's Nervous Systemen_HK
dc.subjectBirth defectsen_HK
dc.subjectFolic aciden_HK
dc.subjectNeural tube defectsen_HK
dc.subjectPrevalenceen_HK
dc.titlePrevalence of neural tube defects in economically and socially deprived area of Chinaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0256-7040&volume=23&issue=10&spage=1119&epage=24&date=2007&atitle=Prevalence+of+Neural+Tube+Defects+in+Economically+and+Socially+Deprived+Area+of+China+en_HK
dc.identifier.emailLin, MC:mcllin@hkucc.hku.hken_HK
dc.identifier.authorityLin, MC=rp00746en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00381-007-0344-3en_HK
dc.identifier.pmid17450368-
dc.identifier.scopuseid_2-s2.0-34548642657en_HK
dc.identifier.hkuros126725en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34548642657&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume23en_HK
dc.identifier.issue10en_HK
dc.identifier.spage1119en_HK
dc.identifier.epage1124en_HK
dc.identifier.isiWOS:000249297600006-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridLiu, J=36014680100en_HK
dc.identifier.scopusauthoridYang, GZ=21740309100en_HK
dc.identifier.scopusauthoridZhou, JL=21740080300en_HK
dc.identifier.scopusauthoridCao, SP=21739272800en_HK
dc.identifier.scopusauthoridChau, DHW=16315084100en_HK
dc.identifier.scopusauthoridKung, HF=7402514190en_HK
dc.identifier.scopusauthoridLin, MC=7404816359en_HK
dc.identifier.citeulike2078502-

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