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Article: Total synthesis of pseudolaric acid A

TitleTotal synthesis of pseudolaric acid A
Authors
KeywordsAntitumor agents
Carbenoids
Domino reactions
Natural products
Total synthesis
Issue Date2006
PublisherWiley - V C H Verlag GmbH & Co. KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/journal/26737/home
Citation
Angewandte Chemie - International Edition, 2006, v. 45 n. 37, p. 6197-6201 How to Cite?
Abstract(Chemical Equation Presented) The antiangiogenic and cytotoxic natural product pseudolaric acid A ((-)-1) has been obtained by a 26-step synthetic route. This enantioselective synthesis employed an intramolecular carbene cyclization cycloaddition cascade reaction as the key step to construct the carbocyclic framework. PMB = para-methoxybenzyl. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
Persistent Identifierhttp://hdl.handle.net/10722/70285
ISSN
2015 Impact Factor: 11.709
2015 SCImago Journal Rankings: 6.229
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorGeng, Zen_HK
dc.contributor.authorChen, Ben_HK
dc.contributor.authorChiu, Pen_HK
dc.date.accessioned2010-09-06T06:21:26Z-
dc.date.available2010-09-06T06:21:26Z-
dc.date.issued2006en_HK
dc.identifier.citationAngewandte Chemie - International Edition, 2006, v. 45 n. 37, p. 6197-6201en_HK
dc.identifier.issn1433-7851en_HK
dc.identifier.urihttp://hdl.handle.net/10722/70285-
dc.description.abstract(Chemical Equation Presented) The antiangiogenic and cytotoxic natural product pseudolaric acid A ((-)-1) has been obtained by a 26-step synthetic route. This enantioselective synthesis employed an intramolecular carbene cyclization cycloaddition cascade reaction as the key step to construct the carbocyclic framework. PMB = para-methoxybenzyl. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.en_HK
dc.languageengen_HK
dc.publisherWiley - V C H Verlag GmbH & Co. KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/journal/26737/homeen_HK
dc.relation.ispartofAngewandte Chemie - International Editionen_HK
dc.subjectAntitumor agentsen_HK
dc.subjectCarbenoidsen_HK
dc.subjectDomino reactionsen_HK
dc.subjectNatural productsen_HK
dc.subjectTotal synthesisen_HK
dc.titleTotal synthesis of pseudolaric acid Aen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1433-7851&volume=45&spage=6197&epage=6201&date=2006&atitle=Total+synthesis+of+pseudolaric+acid+A+en_HK
dc.identifier.emailChiu, P:pchiu@hku.hken_HK
dc.identifier.authorityChiu, P=rp00680en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/anie.200602056en_HK
dc.identifier.pmid16906616-
dc.identifier.scopuseid_2-s2.0-33749006267en_HK
dc.identifier.hkuros124481en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33749006267&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume45en_HK
dc.identifier.issue37en_HK
dc.identifier.spage6197en_HK
dc.identifier.epage6201en_HK
dc.identifier.eissn1521-3773-
dc.identifier.isiWOS:000240815100028-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridGeng, Z=36947090200en_HK
dc.identifier.scopusauthoridChen, B=37160914300en_HK
dc.identifier.scopusauthoridChiu, P=11140148700en_HK

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