File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Biological labelling reagents and probes derived from luminescent transition metal polypyridine complexes

TitleBiological labelling reagents and probes derived from luminescent transition metal polypyridine complexes
Authors
KeywordsBioassays
Iridium(III)
Labelling reagents
Luminescence
Polypyridine complexes
Rhenium(I)
Issue Date2005
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/ccr
Citation
Coordination Chemistry Reviews, 2005, v. 249 n. 13-14, p. 1434-1450 How to Cite?
AbstractMany transition metal polypyridine complexes display intense and long-lived metal-to-ligand charge-transfer emission with a large Stokes' shift. This property renders them promising candidates as luminescent labelling reagents and probes for biological molecules. In view of this, we have designed various biological labels that are derived from luminescent rhenium(I) and iridium(III) polypyridine complexes. These complexes contain various functional groups that can react with the amine and sulfhydryl groups of biomolecules such as oligonucleotides, peptides and protein molecules to form luminescent bioconjugates. In other studies, we have incorporated biotin into luminescent rhenium(I) polypyridine complexes to form new probes for the protein avidin. These new luminescent conjugates and biological probes have been utilised in the development of various bioassays. © 2004 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/70045
ISSN
2015 Impact Factor: 12.994
2015 SCImago Journal Rankings: 4.100
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLo, KKWen_HK
dc.contributor.authorHui, WKen_HK
dc.contributor.authorChung, CKen_HK
dc.contributor.authorTsang, KHKen_HK
dc.contributor.authorNg, DCMen_HK
dc.contributor.authorZhu, Nen_HK
dc.contributor.authorCheung, KKen_HK
dc.date.accessioned2010-09-06T06:19:11Z-
dc.date.available2010-09-06T06:19:11Z-
dc.date.issued2005en_HK
dc.identifier.citationCoordination Chemistry Reviews, 2005, v. 249 n. 13-14, p. 1434-1450en_HK
dc.identifier.issn0010-8545en_HK
dc.identifier.urihttp://hdl.handle.net/10722/70045-
dc.description.abstractMany transition metal polypyridine complexes display intense and long-lived metal-to-ligand charge-transfer emission with a large Stokes' shift. This property renders them promising candidates as luminescent labelling reagents and probes for biological molecules. In view of this, we have designed various biological labels that are derived from luminescent rhenium(I) and iridium(III) polypyridine complexes. These complexes contain various functional groups that can react with the amine and sulfhydryl groups of biomolecules such as oligonucleotides, peptides and protein molecules to form luminescent bioconjugates. In other studies, we have incorporated biotin into luminescent rhenium(I) polypyridine complexes to form new probes for the protein avidin. These new luminescent conjugates and biological probes have been utilised in the development of various bioassays. © 2004 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/ccren_HK
dc.relation.ispartofCoordination Chemistry Reviewsen_HK
dc.rightsCoordination Chemistry Reviews. Copyright © Elsevier BV.en_HK
dc.subjectBioassaysen_HK
dc.subjectIridium(III)en_HK
dc.subjectLabelling reagentsen_HK
dc.subjectLuminescenceen_HK
dc.subjectPolypyridine complexesen_HK
dc.subjectRhenium(I)en_HK
dc.titleBiological labelling reagents and probes derived from luminescent transition metal polypyridine complexesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0010-8545&volume=249&spage=1434&epage=1450&date=2005&atitle=Biological+labelling+reagents+and+probes+derived+from+luminescent+transition+metal+polypyridine+complexesen_HK
dc.identifier.emailZhu, N: nzhu@hkucc.hku.hken_HK
dc.identifier.authorityZhu, N=rp00845en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ccr.2004.10.004en_HK
dc.identifier.scopuseid_2-s2.0-23044443544en_HK
dc.identifier.hkuros117600en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-23044443544&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume249en_HK
dc.identifier.issue13-14en_HK
dc.identifier.spage1434en_HK
dc.identifier.epage1450en_HK
dc.identifier.isiWOS:000231398600014-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridLo, KKW=26032181200en_HK
dc.identifier.scopusauthoridHui, WK=7103196448en_HK
dc.identifier.scopusauthoridChung, CK=7403613700en_HK
dc.identifier.scopusauthoridTsang, KHK=8549213500en_HK
dc.identifier.scopusauthoridNg, DCM=13805259600en_HK
dc.identifier.scopusauthoridZhu, N=7201449530en_HK
dc.identifier.scopusauthoridCheung, KK=7402406613en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats