Article: Possible rules in microRNA target recognition

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TitlePossible rules in microRNA target recognition
AuthorsFu, X
Gu, J
Chan, CY
Lin, MC
Yew, DT
Kung, HF
Lai, L
KeywordsMicroRNAs
Computational prediction
Target recognition
Target-site accessibility
Vertebrates
Issue Date2007
PublisherOmics Group. The Journal's web site is located at http://wwwclassicruscom/IJIB/
CitationInternational Journal of Integrative Biology, 2007, v. 1 n. 3, p. 165-171 [How to Cite?]
AbstractMicroRNAs (miRNAs) play important roles in gene regulatory pathways. Although computational algorithms have been developed for the prediction of miRNA targeting genes in animals, the accuracy of proposed algorithms is far from perfection. Here we present an overview of the proposed algorithms. The possible rules in miRNA target recognition in target predictions are also discussed. A better designed algorithm and further progress on the systemic identification of miRNA targets would enhance our knowledge on their pivotal roles among the biological systems.
ISSN0973-8363
2011 SCImago Journal Rankings: 0.033
DC Field
Value
dc.contributor.authorFu, X
dc.contributor.authorGu, J
dc.contributor.authorChan, CY
dc.contributor.authorLin, MC
dc.contributor.authorYew, DT
dc.contributor.authorKung, HF
dc.contributor.authorLai, L
dc.date.accessioned2010-09-06T06:16:42Z
dc.date.available2010-09-06T06:16:42Z
dc.date.issued2007
dc.description.abstractMicroRNAs (miRNAs) play important roles in gene regulatory pathways. Although computational algorithms have been developed for the prediction of miRNA targeting genes in animals, the accuracy of proposed algorithms is far from perfection. Here we present an overview of the proposed algorithms. The possible rules in miRNA target recognition in target predictions are also discussed. A better designed algorithm and further progress on the systemic identification of miRNA targets would enhance our knowledge on their pivotal roles among the biological systems.
dc.identifier.citationInternational Journal of Integrative Biology, 2007, v. 1 n. 3, p. 165-171 [How to Cite?]
dc.identifier.epage171
dc.identifier.hkuros161285
dc.identifier.issn0973-8363
2011 SCImago Journal Rankings: 0.033
dc.identifier.issue3
dc.identifier.openurl
dc.identifier.spage165
dc.identifier.urihttp://hdl.handle.net/10722/69772
dc.identifier.volume1
dc.languageeng
dc.publisherOmics Group. The Journal's web site is located at http://wwwclassicruscom/IJIB/
dc.relation.ispartofInternational Journal of Integrative Biology
dc.subjectMicroRNAs
dc.subjectComputational prediction
dc.subjectTarget recognition
dc.subjectTarget-site accessibility
dc.subjectVertebrates
dc.titlePossible rules in microRNA target recognition
dc.typeArticle