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Article: Sinoracutine, a novel skeletal alkaloid with cell-protective effects from Sinomenium acutum

TitleSinoracutine, a novel skeletal alkaloid with cell-protective effects from Sinomenium acutum
Authors
Issue Date2009
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/tetlet
Citation
Tetrahedron Letters, 2009, v. 50 n. 30, p. 4375-4377 How to Cite?
AbstractFrom the stems of Sinomenium acutum, sinoracutine (1) has been isolated, an alkaloid with a structurally novel skeletal framework, whose structure has been established by spectral and single crystal X-ray diffraction analysis. In vitro experiments show that sinoracutine increases cell viability against Hydrogen peroxide-induced oxidative injury. © 2009 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/69729
ISSN
2015 Impact Factor: 2.347
2015 SCImago Journal Rankings: 0.782
ISI Accession Number ID
Funding AgencyGrant Number
Natural National Sciences Foundation of China30470187
Science and Technology Commission of Shanghai Municipality06DZ22028
Committee of the Hong Kong Special Administrative Region, ChinaAoE/P-10/01
University of Hong Kong
Funding Information:

We thank Dr. Geoff D. Brown, School of Chemistry, University of Reading, for helpful discussions. The work was supported by grants from the Natural National Sciences Foundation of China (No. 30470187), Science and Technology Commission of Shanghai Municipality (No. 06DZ22028) and the Areas of Excellence Scheme established under the University Grants Committee of the Hong Kong Special Administrative Region, China (Project No. AoE/P-10/01), and the University of Hong Kong.

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorBao, GHen_HK
dc.contributor.authorWang, XLen_HK
dc.contributor.authorTang, XCen_HK
dc.contributor.authorChiu, Pen_HK
dc.contributor.authorQin, GWen_HK
dc.date.accessioned2010-09-06T06:16:19Z-
dc.date.available2010-09-06T06:16:19Z-
dc.date.issued2009en_HK
dc.identifier.citationTetrahedron Letters, 2009, v. 50 n. 30, p. 4375-4377en_HK
dc.identifier.issn0040-4039en_HK
dc.identifier.urihttp://hdl.handle.net/10722/69729-
dc.description.abstractFrom the stems of Sinomenium acutum, sinoracutine (1) has been isolated, an alkaloid with a structurally novel skeletal framework, whose structure has been established by spectral and single crystal X-ray diffraction analysis. In vitro experiments show that sinoracutine increases cell viability against Hydrogen peroxide-induced oxidative injury. © 2009 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/tetleten_HK
dc.relation.ispartofTetrahedron Lettersen_HK
dc.titleSinoracutine, a novel skeletal alkaloid with cell-protective effects from Sinomenium acutumen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0040-4039&volume=50&spage=4375&epage=4377&date=2009&atitle=Sinoracutine,+A+Novel+Skeletal+Alkaloid+With+Cell-protective+Effects+From+Sinomenium+Acutumen_HK
dc.identifier.emailChiu, P:pchiu@hku.hken_HK
dc.identifier.authorityChiu, P=rp00680en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.tetlet.2009.05.040en_HK
dc.identifier.scopuseid_2-s2.0-66449090774en_HK
dc.identifier.hkuros158932en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-66449090774&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume50en_HK
dc.identifier.issue30en_HK
dc.identifier.spage4375en_HK
dc.identifier.epage4377en_HK
dc.identifier.isiWOS:000267495900020-
dc.publisher.placeUnited Kingdomen_HK
dc.relation.projectInstitute of molecular technology for drug discovery and synthesis-
dc.identifier.scopusauthoridBao, GH=7103074512en_HK
dc.identifier.scopusauthoridWang, XL=11639883200en_HK
dc.identifier.scopusauthoridTang, XC=7404100797en_HK
dc.identifier.scopusauthoridChiu, P=11140148700en_HK
dc.identifier.scopusauthoridQin, GW=7202860696en_HK

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