Article: Dihydrochalcones from the leaves of Pieris japonica

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TitleDihydrochalcones from the leaves of Pieris japonica
AuthorsYao, GM1
Ding, Y1
Zuo, JP1
Wang, HB1
Wang, YB1
Ding, BY3
Chiu, P2
Qin, GW1
Issue Date2005
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/jnp
CitationJournal Of Natural Products, 2005, v. 68 n. 3, p. 392-396 [How to Cite?]
DOI: http://dx.doi.org/10.1021/np049698a
AbstractSix new dihydrochalcones, 3-hydroxyasebotin (5), asebogenin 2′-O-β-D-ribohexo-3-ulopyranoside (6), 2″-acetylasebotin (7), 3′,4,5′-trihydroxy-4′-methoxydihydrochalcone 3′,5′-di-O-β-D-glucopyranoside (8), and pierotins A (9) and B (10), along with four known dihydrochalcones, phloretin (1), phlorizin (2), asebogenin (3), and asebotin (4), were isolated from the leaves of Pieris japonica. Their structures were elucidated on the basis of spectroscopic analysis including HMQC, HMBC, NOESY, and X-ray crystal diffraction. Compounds 1, 3-5, and 7-10 inhibited the proliferation of murine B cells and compounds 5 and 10 inhibited the proliferation of murine T cells in vitro significantly. © 2005 American Chemical Society and American Society of Pharmacognosy.
ISSN0163-3864
2011 Impact Factor: 3.128
2011 SCImago Journal Rankings: 0.174
DOIhttp://dx.doi.org/10.1021/np049698a
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorYao, GM
dc.contributor.authorDing, Y
dc.contributor.authorZuo, JP
dc.contributor.authorWang, HB
dc.contributor.authorWang, YB
dc.contributor.authorDing, BY
dc.contributor.authorChiu, P
dc.contributor.authorQin, GW
dc.date.accessioned2010-09-06T06:14:59Z
dc.date.available2010-09-06T06:14:59Z
dc.date.issued2005
dc.description.abstractSix new dihydrochalcones, 3-hydroxyasebotin (5), asebogenin 2′-O-β-D-ribohexo-3-ulopyranoside (6), 2″-acetylasebotin (7), 3′,4,5′-trihydroxy-4′-methoxydihydrochalcone 3′,5′-di-O-β-D-glucopyranoside (8), and pierotins A (9) and B (10), along with four known dihydrochalcones, phloretin (1), phlorizin (2), asebogenin (3), and asebotin (4), were isolated from the leaves of Pieris japonica. Their structures were elucidated on the basis of spectroscopic analysis including HMQC, HMBC, NOESY, and X-ray crystal diffraction. Compounds 1, 3-5, and 7-10 inhibited the proliferation of murine B cells and compounds 5 and 10 inhibited the proliferation of murine T cells in vitro significantly. © 2005 American Chemical Society and American Society of Pharmacognosy.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationJournal Of Natural Products, 2005, v. 68 n. 3, p. 392-396 [How to Cite?]
DOI: http://dx.doi.org/10.1021/np049698a
dc.identifier.doihttp://dx.doi.org/10.1021/np049698a
dc.identifier.epage396
dc.identifier.hkuros98593
dc.identifier.isiWOS:000227927700016
dc.identifier.issn0163-3864
2011 Impact Factor: 3.128
2011 SCImago Journal Rankings: 0.174
dc.identifier.issue3
dc.identifier.openurl
dc.identifier.pmid15787442
dc.identifier.scopuseid_2-s2.0-17444405246
dc.identifier.spage392
dc.identifier.urihttp://hdl.handle.net/10722/69582
dc.identifier.volume68
dc.languageeng
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/jnp
dc.publisher.placeUnited States
dc.relation.ispartofJournal of Natural Products
dc.relation.referencesReferences in Scopus
dc.titleDihydrochalcones from the leaves of Pieris japonica
dc.typeArticle
Author Affiliations
  1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences
  2. The University of Hong Kong
  3. Wenzhou Normal College