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Article: Cancer immunotherapy targeting the telomerase reverse transcriptase.

TitleCancer immunotherapy targeting the telomerase reverse transcriptase.
Authors
Issue Date2006
PublisherChinese Society of Immunology. The Journal's web site is located at http://www.nature.com/cmi/index.html
Citation
Cellular & Molecular Immunology., 2006, v. 3 n. 1, p. 1-11 How to Cite?
AbstractThe human telomerase reverse transcriptase (hTERT) is expressed in more than 85% of tumor cells but is usually not found in normal cells, which makes hTERT as an ideal tumor-associate antigen (TAA) to develop potential vaccine specifically destroying cancers without impairing normal tissues in human cancer immunotherapy. Here are reviewed the fundamental advances of studies on immunogenicity of hTERT or its peptides and the early clinical trials using the hTERT vaccine approach in the last decades.
Persistent Identifierhttp://hdl.handle.net/10722/69537
ISSN
2015 Impact Factor: 5.193
2015 SCImago Journal Rankings: 1.898
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHuo, LFen_HK
dc.contributor.authorTang, JWen_HK
dc.contributor.authorHuang, JJen_HK
dc.contributor.authorHuang, PTen_HK
dc.contributor.authorHuang, CFen_HK
dc.contributor.authorKung, HFen_HK
dc.contributor.authorLin, MCen_HK
dc.date.accessioned2010-09-06T06:14:35Z-
dc.date.available2010-09-06T06:14:35Z-
dc.date.issued2006en_HK
dc.identifier.citationCellular & Molecular Immunology., 2006, v. 3 n. 1, p. 1-11en_HK
dc.identifier.issn1672-7681en_HK
dc.identifier.urihttp://hdl.handle.net/10722/69537-
dc.description.abstractThe human telomerase reverse transcriptase (hTERT) is expressed in more than 85% of tumor cells but is usually not found in normal cells, which makes hTERT as an ideal tumor-associate antigen (TAA) to develop potential vaccine specifically destroying cancers without impairing normal tissues in human cancer immunotherapy. Here are reviewed the fundamental advances of studies on immunogenicity of hTERT or its peptides and the early clinical trials using the hTERT vaccine approach in the last decades.en_HK
dc.languageengen_HK
dc.publisherChinese Society of Immunology. The Journal's web site is located at http://www.nature.com/cmi/index.htmlen_HK
dc.relation.ispartofCellular & molecular immunology.en_HK
dc.titleCancer immunotherapy targeting the telomerase reverse transcriptase.en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1672-7681&volume=3&issue=1&spage=1&epage=11&date=2006&atitle=Cancer+immunotherapy+targeting+the+telomerase+reverse+transcriptaseen_HK
dc.identifier.emailLin, MC:mcllin@hkucc.hku.hken_HK
dc.identifier.authorityLin, MC=rp00746en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid16549043en_HK
dc.identifier.scopuseid_2-s2.0-33745175553en_HK
dc.identifier.hkuros114943en_HK
dc.identifier.volume3en_HK
dc.identifier.issue1en_HK
dc.identifier.spage1en_HK
dc.identifier.epage11en_HK
dc.identifier.isiWOS:000208925800001-
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridHuo, LF=9275343500en_HK
dc.identifier.scopusauthoridTang, JW=14016980900en_HK
dc.identifier.scopusauthoridHuang, JJ=7407194640en_HK
dc.identifier.scopusauthoridHuang, PT=7403658582en_HK
dc.identifier.scopusauthoridHuang, CF=7406879416en_HK
dc.identifier.scopusauthoridKung, HF=7402514190en_HK
dc.identifier.scopusauthoridLin, MC=7404816359en_HK

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