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Article: Deoxyribonucleic acid binding and photocleavage studies of rhenium(I) dipyridophenazine complexes

TitleDeoxyribonucleic acid binding and photocleavage studies of rhenium(I) dipyridophenazine complexes
Authors
Issue Date1997
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/dalton
Citation
Journal Of The Chemical Society - Dalton Transactions, 1997 n. 12, p. 2067-2072 How to Cite?
AbstractThe intercalative binding interaction of [Re(dppz)(CO)3(py)][O3SCF3] (dppz = dipyrido[3,2-a:2′,3′-c]phenazine, py = pyridine) and [Re(dppn)(CO)3(py)][O3SCF3] (dppn = benzo[i]dipyrido[3,2-a:2′,3′-c]phenazine) with double-stranded calf thymus DNA, and synthetic oligonucleotides poly(dA)·poly(dT) and poly(dC)·poly(dG) has been studied with spectroscopic methods. The complexes have been found to promote cleavage of plasmid pBR322 DNA from the supercoiled form I to the open circular form II upon irradiation. The crystal structure of [Re(dppz)(CO)3(py)][O3SCF3] has also been established.
Persistent Identifierhttp://hdl.handle.net/10722/68922
ISSN
1999 Impact Factor: 2.31
References

 

DC FieldValueLanguage
dc.contributor.authorYam, VWWen_HK
dc.contributor.authorLo, KKWen_HK
dc.contributor.authorCheung, KKen_HK
dc.contributor.authorKong, RYCen_HK
dc.date.accessioned2010-09-06T06:08:56Z-
dc.date.available2010-09-06T06:08:56Z-
dc.date.issued1997en_HK
dc.identifier.citationJournal Of The Chemical Society - Dalton Transactions, 1997 n. 12, p. 2067-2072en_HK
dc.identifier.issn0300-9246en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68922-
dc.description.abstractThe intercalative binding interaction of [Re(dppz)(CO)3(py)][O3SCF3] (dppz = dipyrido[3,2-a:2′,3′-c]phenazine, py = pyridine) and [Re(dppn)(CO)3(py)][O3SCF3] (dppn = benzo[i]dipyrido[3,2-a:2′,3′-c]phenazine) with double-stranded calf thymus DNA, and synthetic oligonucleotides poly(dA)·poly(dT) and poly(dC)·poly(dG) has been studied with spectroscopic methods. The complexes have been found to promote cleavage of plasmid pBR322 DNA from the supercoiled form I to the open circular form II upon irradiation. The crystal structure of [Re(dppz)(CO)3(py)][O3SCF3] has also been established.en_HK
dc.languageengen_HK
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/daltonen_HK
dc.relation.ispartofJournal of the Chemical Society - Dalton Transactionsen_HK
dc.titleDeoxyribonucleic acid binding and photocleavage studies of rhenium(I) dipyridophenazine complexesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1472-7773&volume=Issue No 12&spage=2067&epage=2072&date=1997&atitle=Deoxyribonucleic+acid+binding+and+photocleavage+studies+of+rhenium(I)+dipyridophenazine+complexesen_HK
dc.identifier.emailYam, VWW:wwyam@hku.hken_HK
dc.identifier.authorityYam, VWW=rp00822en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1039/A700828G-
dc.identifier.scopuseid_2-s2.0-33748502521en_HK
dc.identifier.hkuros25831en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33748502521&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.issue12en_HK
dc.identifier.spage2067en_HK
dc.identifier.epage2072en_HK
dc.identifier.scopusauthoridYam, VWW=18539304700en_HK
dc.identifier.scopusauthoridLo, KKW=26032181200en_HK
dc.identifier.scopusauthoridCheung, KK=7402406613en_HK
dc.identifier.scopusauthoridKong, RYC=7005290687en_HK

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