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Article: A simple, regioselective synthesis of 1,4-bis(tert-butoxycarbonylmethyl)-tetraazacyclododecane

TitleA simple, regioselective synthesis of 1,4-bis(tert-butoxycarbonylmethyl)-tetraazacyclododecane
Authors
Issue Date2003
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/joc
Citation
Journal Of Organic Chemistry, 2003, v. 68 n. 7, p. 2956-2959 How to Cite?
AbstractA convenient synthetic route to 1,4-bis(tert-butoxycarbonylmethyl)tetraazacyclododecane (cyclen) (1) with high yield and excellent regioselectivity is described. Compound 1 reacted with a range of functionalized alkyl halides under two reaction conditions to give mono-N-alkylated 1,4-bis(tert-butoxycarbonylmethyl)tetraazacyclododecane (2-9) in good yield.
Persistent Identifierhttp://hdl.handle.net/10722/68885
ISSN
2015 Impact Factor: 4.785
2015 SCImago Journal Rankings: 2.095
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLi, Cen_HK
dc.contributor.authorWong, WTen_HK
dc.date.accessioned2010-09-06T06:08:36Z-
dc.date.available2010-09-06T06:08:36Z-
dc.date.issued2003en_HK
dc.identifier.citationJournal Of Organic Chemistry, 2003, v. 68 n. 7, p. 2956-2959en_HK
dc.identifier.issn0022-3263en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68885-
dc.description.abstractA convenient synthetic route to 1,4-bis(tert-butoxycarbonylmethyl)tetraazacyclododecane (cyclen) (1) with high yield and excellent regioselectivity is described. Compound 1 reacted with a range of functionalized alkyl halides under two reaction conditions to give mono-N-alkylated 1,4-bis(tert-butoxycarbonylmethyl)tetraazacyclododecane (2-9) in good yield.en_HK
dc.languageengen_HK
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/jocen_HK
dc.relation.ispartofJournal of Organic Chemistryen_HK
dc.titleA simple, regioselective synthesis of 1,4-bis(tert-butoxycarbonylmethyl)-tetraazacyclododecaneen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-3263&volume=68&issue=7&spage=2956&epage=2959&date=2003&atitle=A+simple,+regioselective+synthesis+of+1-4-Bis(tert-butoxycarbonylmethyl)-tetraazacyclododecaneen_HK
dc.identifier.emailWong, WT: wtwong@hku.hken_HK
dc.identifier.authorityWong, WT=rp00811en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/jo026436+en_HK
dc.identifier.scopuseid_2-s2.0-0037419165en_HK
dc.identifier.hkuros82701en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037419165&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume68en_HK
dc.identifier.issue7en_HK
dc.identifier.spage2956en_HK
dc.identifier.epage2959en_HK
dc.identifier.isiWOS:000181953700056-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLi, C=8521804400en_HK
dc.identifier.scopusauthoridWong, WT=7403973084en_HK

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