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Article: Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extraction

TitlePreparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extraction
Authors
KeywordsMatrine
Molecularly imprinted microspheres
Solid-phase extraction
Sophora flavescens
Issue Date2003
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00216/index.htm
Citation
Analytical And Bioanalytical Chemistry, 2003, v. 375 n. 2, p. 264-269 How to Cite?
AbstractMolecularly imprinted microspheres (MIMs) were synthesized by micro-suspension polymerization using matrine (MT) as template. The MIMs were employed for solid-phase extraction (SPE) and as Chromatographic stationary phase for the determination of MT from the Chinese medicinal plant Sophora flavescens. The effects of the various eluents, their concentrations and volumes on the retention behavior were investigated. The selectivity and capacity of the imprinted microspheres against MT was also discussed. The results showed that the MIMs exhibited stronger specific affinity to MT than to oxymatrine (OMT). Methanol-water (3:7, v/v) was used for washing impurities from the MIMs-SPE cartridge loaded with the herb extracts, while methanol-glacial acetic acid (9:1, v/v) was used for eluting MT. The maximum load of MT and the recovery of MIMs cartridge towards MT were 38.7 μg g -1 and 71.4%, respectively. The method developed might be used to separate and extract effective constituents from Chinese medicinal plants on a large scale. © Springer-Verlag 2002.
Persistent Identifierhttp://hdl.handle.net/10722/68692
ISSN
2015 Impact Factor: 3.125
2015 SCImago Journal Rankings: 1.096
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLai, JPen_HK
dc.contributor.authorHe, XWen_HK
dc.contributor.authorJiang, Yen_HK
dc.contributor.authorChen, Fen_HK
dc.date.accessioned2010-09-06T06:06:48Z-
dc.date.available2010-09-06T06:06:48Z-
dc.date.issued2003en_HK
dc.identifier.citationAnalytical And Bioanalytical Chemistry, 2003, v. 375 n. 2, p. 264-269en_HK
dc.identifier.issn1618-2642en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68692-
dc.description.abstractMolecularly imprinted microspheres (MIMs) were synthesized by micro-suspension polymerization using matrine (MT) as template. The MIMs were employed for solid-phase extraction (SPE) and as Chromatographic stationary phase for the determination of MT from the Chinese medicinal plant Sophora flavescens. The effects of the various eluents, their concentrations and volumes on the retention behavior were investigated. The selectivity and capacity of the imprinted microspheres against MT was also discussed. The results showed that the MIMs exhibited stronger specific affinity to MT than to oxymatrine (OMT). Methanol-water (3:7, v/v) was used for washing impurities from the MIMs-SPE cartridge loaded with the herb extracts, while methanol-glacial acetic acid (9:1, v/v) was used for eluting MT. The maximum load of MT and the recovery of MIMs cartridge towards MT were 38.7 μg g -1 and 71.4%, respectively. The method developed might be used to separate and extract effective constituents from Chinese medicinal plants on a large scale. © Springer-Verlag 2002.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00216/index.htmen_HK
dc.relation.ispartofAnalytical and Bioanalytical Chemistryen_HK
dc.subjectMatrineen_HK
dc.subjectMolecularly imprinted microspheresen_HK
dc.subjectSolid-phase extractionen_HK
dc.subjectSophora flavescensen_HK
dc.titlePreparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extractionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1618-2642&volume=375&spage=264&epage=269&date=2003&atitle=Preparative+separation+and+determination+of+matrine+from+the+Chinese+medicinal+plant+Sophora+flavescens+Ait+by+molecularly+imprinted+solid+phase+extractionen_HK
dc.identifier.emailChen, F: sfchen@hku.hken_HK
dc.identifier.authorityChen, F=rp00672en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00216-002-1675-2en_HK
dc.identifier.pmid12560971-
dc.identifier.scopuseid_2-s2.0-0037264313en_HK
dc.identifier.hkuros80797en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037264313&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume375en_HK
dc.identifier.issue2en_HK
dc.identifier.spage264en_HK
dc.identifier.epage269en_HK
dc.identifier.isiWOS:000181104300010-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridLai, JP=7401939703en_HK
dc.identifier.scopusauthoridHe, XW=7404409073en_HK
dc.identifier.scopusauthoridJiang, Y=24605346600en_HK
dc.identifier.scopusauthoridChen, F=7404907980en_HK

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