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Article: Mass spectrometry-based "omics" technologies in cancer diagnostics

TitleMass spectrometry-based "omics" technologies in cancer diagnostics
Authors
Keywords"omics"
Bioinformatics
Biomarker discovery
Cancer
Mass spectrometry
Molecular diagnosis
Issue Date2007
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0277-7037/
Citation
Mass Spectrometry Reviews, 2007, v. 26 n. 3, p. 403-431 How to Cite?
AbstractMany "omics" techniques have been developed for one goal: biomarker discovery and early diagnosis of human cancers. A comprehensive review of mass spectrometry-based "omics" approaches performed on various biological samples for molecular diagnosis of human cancers is presented in this article. Furthermore, the existing and potential problems/solutions (both de facto experimental and bioinformatic challenges), and future prospects have been extensively discussed. Although the use of present omic methods as diagnostic tools are still in their infant stage and consequently not ready for immediate clinical use, it can be envisaged that the "omics"-based cancer diagnostics will gradually enter into the clinic in next 10 years as an important supplement to current clinical diagnostics. @ 2007 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/68544
ISSN
2015 Impact Factor: 9.346
2015 SCImago Journal Rankings: 2.504
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhang, Xen_HK
dc.contributor.authorWei, Den_HK
dc.contributor.authorYap, Yen_HK
dc.contributor.authorLi, Len_HK
dc.contributor.authorGuo, Sen_HK
dc.contributor.authorChen, Fen_HK
dc.date.accessioned2010-09-06T06:05:33Z-
dc.date.available2010-09-06T06:05:33Z-
dc.date.issued2007en_HK
dc.identifier.citationMass Spectrometry Reviews, 2007, v. 26 n. 3, p. 403-431en_HK
dc.identifier.issn0277-7037en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68544-
dc.description.abstractMany "omics" techniques have been developed for one goal: biomarker discovery and early diagnosis of human cancers. A comprehensive review of mass spectrometry-based "omics" approaches performed on various biological samples for molecular diagnosis of human cancers is presented in this article. Furthermore, the existing and potential problems/solutions (both de facto experimental and bioinformatic challenges), and future prospects have been extensively discussed. Although the use of present omic methods as diagnostic tools are still in their infant stage and consequently not ready for immediate clinical use, it can be envisaged that the "omics"-based cancer diagnostics will gradually enter into the clinic in next 10 years as an important supplement to current clinical diagnostics. @ 2007 Wiley Periodicals, Inc.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0277-7037/en_HK
dc.relation.ispartofMass Spectrometry Reviewsen_HK
dc.rightsMass Spectrometry Reviews. Copyright © John Wiley & Sons, Inc.en_HK
dc.subject"omics"en_HK
dc.subjectBioinformaticsen_HK
dc.subjectBiomarker discoveryen_HK
dc.subjectCanceren_HK
dc.subjectMass spectrometryen_HK
dc.subjectMolecular diagnosisen_HK
dc.titleMass spectrometry-based "omics" technologies in cancer diagnosticsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0277-7037&volume=26&spage=403&epage=431&date=2007&atitle=Mass+spectrometry-based+%27omics%27+technologies+in+cancer+diagnosticsen_HK
dc.identifier.emailChen, F: sfchen@hku.hken_HK
dc.identifier.authorityChen, F=rp00672en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/mas.20132en_HK
dc.identifier.pmid17405143-
dc.identifier.scopuseid_2-s2.0-34248545254en_HK
dc.identifier.hkuros137104en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34248545254&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume26en_HK
dc.identifier.issue3en_HK
dc.identifier.spage403en_HK
dc.identifier.epage431en_HK
dc.identifier.isiWOS:000246117300006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridZhang, X=16044335800en_HK
dc.identifier.scopusauthoridWei, D=24472144100en_HK
dc.identifier.scopusauthoridYap, Y=7005551975en_HK
dc.identifier.scopusauthoridLi, L=26642911300en_HK
dc.identifier.scopusauthoridGuo, S=8514940700en_HK
dc.identifier.scopusauthoridChen, F=7404907980en_HK
dc.identifier.citeulike2184190-

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