Article: Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer

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TitleAntioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
AuthorsCai, Y1
Luo, Q2
Sun, M1
Corke, H1
KeywordsABTS
Anticancer
Antioxidant activity
Flavonoids
Free radical
Phenolic acids
Phenolic compounds
Quinones
Tannins
Traditional Chinese Medicines
Issue Date2004
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie
CitationLife Sciences, 2004, v. 74 n. 17, p. 2157-2184 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.lfs.2003.09.047
AbstractCancer prevention and treatment using traditional Chinese medicines have attracted increasing interest. This study characterizes antioxidant activity and phenolic compounds of traditional Chinese medicinal plants associated with anticancer, comprising 112 species from 50 plant families. The improved ABTS •+ method was used to systematically assess the total antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC) of the medicinal extracts. The TEAC values and total phenolic content for methanolic extracts of herbs ranged from 46.7 to 17,323 μmol Trolox equivalent/100 g dry weight (DW), and from 0.22 to 50.3 g of gallic acid equivalent/100 g DW, respectively. A positive, significant linear relationship between antioxidant activity and total phenolic content (all R 2 values≥0.95) showed that phenolic compounds were the dominant antioxidant components in the tested medicinal herbs. Major types of phenolic compounds from most of the tested herbs were preliminarily identified and analyzed, and mainly included phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes, and curcuminoids. These medicinal herbs exhibited far stronger antioxidant activity and contained significantly higher levels of phenolics than common vegetables and fruits. Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents. © 2003 Published by Elsevier Inc.
ISSN0024-3205
2011 Impact Factor: 2.527
2011 SCImago Journal Rankings: 0.189
DOIhttp://dx.doi.org/10.1016/j.lfs.2003.09.047
ISI Accession Number IDWOS:000189221100006
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorCai, Y
dc.contributor.authorLuo, Q
dc.contributor.authorSun, M
dc.contributor.authorCorke, H
dc.date.accessioned2010-09-06T06:05:10Z
dc.date.available2010-09-06T06:05:10Z
dc.date.issued2004
dc.description.abstractCancer prevention and treatment using traditional Chinese medicines have attracted increasing interest. This study characterizes antioxidant activity and phenolic compounds of traditional Chinese medicinal plants associated with anticancer, comprising 112 species from 50 plant families. The improved ABTS •+ method was used to systematically assess the total antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC) of the medicinal extracts. The TEAC values and total phenolic content for methanolic extracts of herbs ranged from 46.7 to 17,323 μmol Trolox equivalent/100 g dry weight (DW), and from 0.22 to 50.3 g of gallic acid equivalent/100 g DW, respectively. A positive, significant linear relationship between antioxidant activity and total phenolic content (all R 2 values≥0.95) showed that phenolic compounds were the dominant antioxidant components in the tested medicinal herbs. Major types of phenolic compounds from most of the tested herbs were preliminarily identified and analyzed, and mainly included phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes, and curcuminoids. These medicinal herbs exhibited far stronger antioxidant activity and contained significantly higher levels of phenolics than common vegetables and fruits. Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents. © 2003 Published by Elsevier Inc.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationLife Sciences, 2004, v. 74 n. 17, p. 2157-2184 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.lfs.2003.09.047
dc.identifier.doihttp://dx.doi.org/10.1016/j.lfs.2003.09.047
dc.identifier.epage2184
dc.identifier.hkuros91093
dc.identifier.isiWOS:000189221100006
dc.identifier.issn0024-3205
2011 Impact Factor: 2.527
2011 SCImago Journal Rankings: 0.189
dc.identifier.issue17
dc.identifier.openurl
dc.identifier.pmid14969719
dc.identifier.scopuseid_2-s2.0-1142297395
dc.identifier.spage2157
dc.identifier.urihttp://hdl.handle.net/10722/68501
dc.identifier.volume74
dc.languageeng
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie
dc.publisher.placeUnited States
dc.relation.ispartofLife Sciences
dc.relation.referencesReferences in Scopus
dc.subject.meshAntineoplastic Agents, Phytogenic
dc.subject.meshAntioxidants - analysis
dc.subject.meshDrugs, Chinese Herbal - chemistry
dc.subject.meshPhenols - analysis - chemistry
dc.subject.meshPlant Extracts - chemistry
dc.subjectABTS
dc.subjectAnticancer
dc.subjectAntioxidant activity
dc.subjectFlavonoids
dc.subjectFree radical
dc.subjectPhenolic acids
dc.subjectPhenolic compounds
dc.subjectQuinones
dc.subjectTannins
dc.subjectTraditional Chinese Medicines
dc.titleAntioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Wuhan University