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Article: Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
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TitleAntioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
 
AuthorsCai, Y1
Luo, Q2
Sun, M1
Corke, H1
 
KeywordsABTS
Anticancer
Antioxidant activity
Flavonoids
Free radical
Phenolic acids
Phenolic compounds
Quinones
Tannins
Traditional Chinese Medicines
 
Issue Date2004
 
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie
 
CitationLife Sciences, 2004, v. 74 n. 17, p. 2157-2184 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.lfs.2003.09.047
 
AbstractCancer prevention and treatment using traditional Chinese medicines have attracted increasing interest. This study characterizes antioxidant activity and phenolic compounds of traditional Chinese medicinal plants associated with anticancer, comprising 112 species from 50 plant families. The improved ABTS •+ method was used to systematically assess the total antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC) of the medicinal extracts. The TEAC values and total phenolic content for methanolic extracts of herbs ranged from 46.7 to 17,323 μmol Trolox equivalent/100 g dry weight (DW), and from 0.22 to 50.3 g of gallic acid equivalent/100 g DW, respectively. A positive, significant linear relationship between antioxidant activity and total phenolic content (all R 2 values≥0.95) showed that phenolic compounds were the dominant antioxidant components in the tested medicinal herbs. Major types of phenolic compounds from most of the tested herbs were preliminarily identified and analyzed, and mainly included phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes, and curcuminoids. These medicinal herbs exhibited far stronger antioxidant activity and contained significantly higher levels of phenolics than common vegetables and fruits. Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents. © 2003 Published by Elsevier Inc.
 
ISSN0024-3205
2013 Impact Factor: 2.296
2013 SCImago Journal Rankings: 0.962
 
DOIhttp://dx.doi.org/10.1016/j.lfs.2003.09.047
 
ISI Accession Number IDWOS:000189221100006
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorCai, Y
 
dc.contributor.authorLuo, Q
 
dc.contributor.authorSun, M
 
dc.contributor.authorCorke, H
 
dc.date.accessioned2010-09-06T06:05:10Z
 
dc.date.available2010-09-06T06:05:10Z
 
dc.date.issued2004
 
dc.description.abstractCancer prevention and treatment using traditional Chinese medicines have attracted increasing interest. This study characterizes antioxidant activity and phenolic compounds of traditional Chinese medicinal plants associated with anticancer, comprising 112 species from 50 plant families. The improved ABTS •+ method was used to systematically assess the total antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC) of the medicinal extracts. The TEAC values and total phenolic content for methanolic extracts of herbs ranged from 46.7 to 17,323 μmol Trolox equivalent/100 g dry weight (DW), and from 0.22 to 50.3 g of gallic acid equivalent/100 g DW, respectively. A positive, significant linear relationship between antioxidant activity and total phenolic content (all R 2 values≥0.95) showed that phenolic compounds were the dominant antioxidant components in the tested medicinal herbs. Major types of phenolic compounds from most of the tested herbs were preliminarily identified and analyzed, and mainly included phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes, and curcuminoids. These medicinal herbs exhibited far stronger antioxidant activity and contained significantly higher levels of phenolics than common vegetables and fruits. Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents. © 2003 Published by Elsevier Inc.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationLife Sciences, 2004, v. 74 n. 17, p. 2157-2184 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.lfs.2003.09.047
 
dc.identifier.doihttp://dx.doi.org/10.1016/j.lfs.2003.09.047
 
dc.identifier.epage2184
 
dc.identifier.hkuros91093
 
dc.identifier.isiWOS:000189221100006
 
dc.identifier.issn0024-3205
2013 Impact Factor: 2.296
2013 SCImago Journal Rankings: 0.962
 
dc.identifier.issue17
 
dc.identifier.openurl
 
dc.identifier.pmid14969719
 
dc.identifier.scopuseid_2-s2.0-1142297395
 
dc.identifier.spage2157
 
dc.identifier.urihttp://hdl.handle.net/10722/68501
 
dc.identifier.volume74
 
dc.languageeng
 
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie
 
dc.publisher.placeUnited States
 
dc.relation.ispartofLife Sciences
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAntineoplastic Agents, Phytogenic
 
dc.subject.meshAntioxidants - analysis
 
dc.subject.meshDrugs, Chinese Herbal - chemistry
 
dc.subject.meshPhenols - analysis - chemistry
 
dc.subject.meshPlant Extracts - chemistry
 
dc.subjectABTS
 
dc.subjectAnticancer
 
dc.subjectAntioxidant activity
 
dc.subjectFlavonoids
 
dc.subjectFree radical
 
dc.subjectPhenolic acids
 
dc.subjectPhenolic compounds
 
dc.subjectQuinones
 
dc.subjectTannins
 
dc.subjectTraditional Chinese Medicines
 
dc.titleAntioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong
  2. Wuhan University