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Article: The prenatal expression of secretin receptor

TitleThe prenatal expression of secretin receptor
Authors
KeywordsDevelopment
Embryo
Expression
Prenatal
Secretin receptor
Issue Date2006
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.blackwellpublishing.com/journal.asp?ref=0077-8923&site=1
Citation
Annals Of The New York Academy Of Sciences, 2006, v. 1070, p. 561-565 How to Cite?
AbstractSecretin is a classical gastrointestinal peptide while its neuroactive functions in the central nervous system have recently been consolidated. In the past, there was little information regarding the expression of secretin receptor in prenatal development. In this article, using mouse embryos and by in situ hybridization, secretin receptor transcripts were detected in several developing brain regions including the cerebellar primordium and choroid plexus. In the developing intestine, secretin receptor is present in the epithelial lining of the villi and the inner circular muscle. Interestingly, the transcripts for secretin receptor were also detected in the epicardium and myocardium of the developing heart as well as the glomerulus and collecting duct in the developing kidney. Taken together, our data suggest a potential pleiotrophic role of secretin during embryonic development. © 2006 New York Academy of Sciences.
Persistent Identifierhttp://hdl.handle.net/10722/68248
ISSN
2015 Impact Factor: 4.518
2015 SCImago Journal Rankings: 2.389
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSiu, FKYen_HK
dc.contributor.authorSham, MHen_HK
dc.contributor.authorChow, BKCen_HK
dc.date.accessioned2010-09-06T06:02:46Z-
dc.date.available2010-09-06T06:02:46Z-
dc.date.issued2006en_HK
dc.identifier.citationAnnals Of The New York Academy Of Sciences, 2006, v. 1070, p. 561-565en_HK
dc.identifier.issn0077-8923en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68248-
dc.description.abstractSecretin is a classical gastrointestinal peptide while its neuroactive functions in the central nervous system have recently been consolidated. In the past, there was little information regarding the expression of secretin receptor in prenatal development. In this article, using mouse embryos and by in situ hybridization, secretin receptor transcripts were detected in several developing brain regions including the cerebellar primordium and choroid plexus. In the developing intestine, secretin receptor is present in the epithelial lining of the villi and the inner circular muscle. Interestingly, the transcripts for secretin receptor were also detected in the epicardium and myocardium of the developing heart as well as the glomerulus and collecting duct in the developing kidney. Taken together, our data suggest a potential pleiotrophic role of secretin during embryonic development. © 2006 New York Academy of Sciences.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.blackwellpublishing.com/journal.asp?ref=0077-8923&site=1en_HK
dc.relation.ispartofAnnals of the New York Academy of Sciencesen_HK
dc.subjectDevelopmenten_HK
dc.subjectEmbryoen_HK
dc.subjectExpressionen_HK
dc.subjectPrenatalen_HK
dc.subjectSecretin receptoren_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshCentral Nervous System - embryology - metabolismen_HK
dc.subject.meshGene Expression Regulation, Developmentalen_HK
dc.subject.meshIn Situ Hybridizationen_HK
dc.subject.meshMiceen_HK
dc.subject.meshReceptors, G-Protein-Coupled - geneticsen_HK
dc.subject.meshReceptors, Gastrointestinal Hormone - geneticsen_HK
dc.titleThe prenatal expression of secretin receptoren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0077-8923&volume=1070&spage=p561&epage=565&date=2006&atitle=The+prenatal+expression+of+secretin+receptoren_HK
dc.identifier.emailSham, MH: mhsham@hku.hken_HK
dc.identifier.emailChow, BKC: bkcc@hku.hken_HK
dc.identifier.authoritySham, MH=rp00380en_HK
dc.identifier.authorityChow, BKC=rp00681en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1196/annals.1317.081en_HK
dc.identifier.pmid16888225en_HK
dc.identifier.scopuseid_2-s2.0-33746390105en_HK
dc.identifier.hkuros122740en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33746390105&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume1070en_HK
dc.identifier.spage561en_HK
dc.identifier.epage565en_HK
dc.identifier.isiWOS:000240364200083-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSiu, FKY=6701518484en_HK
dc.identifier.scopusauthoridSham, MH=7003729109en_HK
dc.identifier.scopusauthoridChow, BKC=7102826193en_HK

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