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- Publisher Website: 10.1093/bioinformatics/btm458
- Scopus: eid_2-s2.0-36448983553
- PMID: 17872914
- WOS: WOS:000251197800024
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Article: IGG: A tool to integrate GeneChips for genetic studies
Title | IGG: A tool to integrate GeneChips for genetic studies |
---|---|
Authors | |
Issue Date | 2007 |
Publisher | Oxford University Press. The Journal's web site is located at http://bioinformatics.oxfordjournals.org/ |
Citation | Bioinformatics, 2007, v. 23 n. 22, p. 3105-3107 How to Cite? |
Abstract | Summary: To facilitate genetic studies using high-throughput genotyping technologies, we have developed an open source tool to integrate genotype data across the Affymetrix and Illumina platforms. It can efficiently integrate a large amount of data from various GeneChips, add genotypes of the HapMap Project into a specific project, flexibly trim and export the integrated data with different formats of popular genetic analysis tools, and highly control the quality of genotype data. Furthermore, this tool has sufficiently simplified its usage through its user-friendly graphic interface and is independent of third-party databases. IGG has successfully been applied to a genome-wide linkage scan in a Charcot-Marie-Tooth disease pedigree by integrating three types of GeneChips and HapMap project genotypes. © The Author 2007. Published by Oxford University Press. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/68111 |
ISSN | 2023 Impact Factor: 4.4 2023 SCImago Journal Rankings: 2.574 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Li, MX | en_HK |
dc.contributor.author | Jiang, L | en_HK |
dc.contributor.author | Ho, SL | en_HK |
dc.contributor.author | Song, YQ | en_HK |
dc.contributor.author | Sham, PC | en_HK |
dc.date.accessioned | 2010-09-06T06:01:26Z | - |
dc.date.available | 2010-09-06T06:01:26Z | - |
dc.date.issued | 2007 | en_HK |
dc.identifier.citation | Bioinformatics, 2007, v. 23 n. 22, p. 3105-3107 | en_HK |
dc.identifier.issn | 1367-4803 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/68111 | - |
dc.description.abstract | Summary: To facilitate genetic studies using high-throughput genotyping technologies, we have developed an open source tool to integrate genotype data across the Affymetrix and Illumina platforms. It can efficiently integrate a large amount of data from various GeneChips, add genotypes of the HapMap Project into a specific project, flexibly trim and export the integrated data with different formats of popular genetic analysis tools, and highly control the quality of genotype data. Furthermore, this tool has sufficiently simplified its usage through its user-friendly graphic interface and is independent of third-party databases. IGG has successfully been applied to a genome-wide linkage scan in a Charcot-Marie-Tooth disease pedigree by integrating three types of GeneChips and HapMap project genotypes. © The Author 2007. Published by Oxford University Press. All rights reserved. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Oxford University Press. The Journal's web site is located at http://bioinformatics.oxfordjournals.org/ | en_HK |
dc.relation.ispartof | Bioinformatics | en_HK |
dc.subject.mesh | Algorithms | - |
dc.subject.mesh | Databases, Genetic | - |
dc.subject.mesh | Gene Expression Profiling - instrumentation - methods | - |
dc.subject.mesh | Information Storage and Retrieval - methods | - |
dc.subject.mesh | Oligonucleotide Array Sequence Analysis - instrumentation - methods | - |
dc.title | IGG: A tool to integrate GeneChips for genetic studies | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Li, MX: mxli@hku.hk | en_HK |
dc.identifier.email | Ho, SL: slho@hku.hk | en_HK |
dc.identifier.email | Song, YQ: songy@hku.hk | en_HK |
dc.identifier.email | Sham, PC: pcsham@hku.hk | en_HK |
dc.identifier.authority | Li, MX=rp01722 | en_HK |
dc.identifier.authority | Ho, SL=rp00240 | en_HK |
dc.identifier.authority | Song, YQ=rp00488 | en_HK |
dc.identifier.authority | Sham, PC=rp00459 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1093/bioinformatics/btm458 | en_HK |
dc.identifier.pmid | 17872914 | en_HK |
dc.identifier.scopus | eid_2-s2.0-36448983553 | en_HK |
dc.identifier.hkuros | 139063 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-36448983553&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 23 | en_HK |
dc.identifier.issue | 22 | en_HK |
dc.identifier.spage | 3105 | en_HK |
dc.identifier.epage | 3107 | en_HK |
dc.identifier.isi | WOS:000251197800024 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Li, MX=17135391100 | en_HK |
dc.identifier.scopusauthorid | Jiang, L=23012303800 | en_HK |
dc.identifier.scopusauthorid | Ho, SL=25959633500 | en_HK |
dc.identifier.scopusauthorid | Song, YQ=7404921212 | en_HK |
dc.identifier.scopusauthorid | Sham, PC=34573429300 | en_HK |
dc.identifier.citeulike | 1700189 | - |
dc.identifier.issnl | 1367-4803 | - |