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Article: IGG: A tool to integrate GeneChips for genetic studies

TitleIGG: A tool to integrate GeneChips for genetic studies
Authors
Issue Date2007
PublisherOxford University Press. The Journal's web site is located at http://bioinformatics.oxfordjournals.org/
Citation
Bioinformatics, 2007, v. 23 n. 22, p. 3105-3107 How to Cite?
AbstractSummary: To facilitate genetic studies using high-throughput genotyping technologies, we have developed an open source tool to integrate genotype data across the Affymetrix and Illumina platforms. It can efficiently integrate a large amount of data from various GeneChips, add genotypes of the HapMap Project into a specific project, flexibly trim and export the integrated data with different formats of popular genetic analysis tools, and highly control the quality of genotype data. Furthermore, this tool has sufficiently simplified its usage through its user-friendly graphic interface and is independent of third-party databases. IGG has successfully been applied to a genome-wide linkage scan in a Charcot-Marie-Tooth disease pedigree by integrating three types of GeneChips and HapMap project genotypes. © The Author 2007. Published by Oxford University Press. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/68111
ISSN
2015 Impact Factor: 5.766
2015 SCImago Journal Rankings: 4.643
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLi, MXen_HK
dc.contributor.authorJiang, Len_HK
dc.contributor.authorHo, SLen_HK
dc.contributor.authorSong, YQen_HK
dc.contributor.authorSham, PCen_HK
dc.date.accessioned2010-09-06T06:01:26Z-
dc.date.available2010-09-06T06:01:26Z-
dc.date.issued2007en_HK
dc.identifier.citationBioinformatics, 2007, v. 23 n. 22, p. 3105-3107en_HK
dc.identifier.issn1367-4803en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68111-
dc.description.abstractSummary: To facilitate genetic studies using high-throughput genotyping technologies, we have developed an open source tool to integrate genotype data across the Affymetrix and Illumina platforms. It can efficiently integrate a large amount of data from various GeneChips, add genotypes of the HapMap Project into a specific project, flexibly trim and export the integrated data with different formats of popular genetic analysis tools, and highly control the quality of genotype data. Furthermore, this tool has sufficiently simplified its usage through its user-friendly graphic interface and is independent of third-party databases. IGG has successfully been applied to a genome-wide linkage scan in a Charcot-Marie-Tooth disease pedigree by integrating three types of GeneChips and HapMap project genotypes. © The Author 2007. Published by Oxford University Press. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://bioinformatics.oxfordjournals.org/en_HK
dc.relation.ispartofBioinformaticsen_HK
dc.subject.meshAlgorithms-
dc.subject.meshDatabases, Genetic-
dc.subject.meshGene Expression Profiling - instrumentation - methods-
dc.subject.meshInformation Storage and Retrieval - methods-
dc.subject.meshOligonucleotide Array Sequence Analysis - instrumentation - methods-
dc.titleIGG: A tool to integrate GeneChips for genetic studiesen_HK
dc.typeArticleen_HK
dc.identifier.emailLi, MX: mxli@hku.hken_HK
dc.identifier.emailHo, SL: slho@hku.hken_HK
dc.identifier.emailSong, YQ: songy@hku.hken_HK
dc.identifier.emailSham, PC: pcsham@hku.hken_HK
dc.identifier.authorityLi, MX=rp01722en_HK
dc.identifier.authorityHo, SL=rp00240en_HK
dc.identifier.authoritySong, YQ=rp00488en_HK
dc.identifier.authoritySham, PC=rp00459en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/bioinformatics/btm458en_HK
dc.identifier.pmid17872914en_HK
dc.identifier.scopuseid_2-s2.0-36448983553en_HK
dc.identifier.hkuros139063en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-36448983553&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume23en_HK
dc.identifier.issue22en_HK
dc.identifier.spage3105en_HK
dc.identifier.epage3107en_HK
dc.identifier.isiWOS:000251197800024-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLi, MX=17135391100en_HK
dc.identifier.scopusauthoridJiang, L=23012303800en_HK
dc.identifier.scopusauthoridHo, SL=25959633500en_HK
dc.identifier.scopusauthoridSong, YQ=7404921212en_HK
dc.identifier.scopusauthoridSham, PC=34573429300en_HK
dc.identifier.citeulike1700189-

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