File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Nedocromil sodium in the management of chronic bronchial infection

TitleNedocromil sodium in the management of chronic bronchial infection
Authors
Issue Date1993
PublisherBlackwell Publishing Ltd.
Citation
Journal Of Clinical Pharmacy And Therapeutics, 1993, v. 18 n. 5, p. 337-341 How to Cite?
AbstractA double-blind parallel group comparative pilot study was carried out in patients with bronchiectasis to evaluate the anti-inflammatory effect of nedocromil sodium in chronic bronchial infection. Patients were randomized to either a nedocromil sodium metered dose inhaler, 4 mg, four times daily, or placebo for 12 weeks. Clinical symptoms, lung function tests and sputum characteristics of volume, purulence, leucocyte count, neutrophil chemotactic activity and elastolytic activity were evaluated at baseline, after 4, 8 and 12 weeks of the trial. Patients were withdrawn when they had acute infective exacerbation. There were 13 evaluable patients and results were statistically analysed at 8 weeks due to the limited number of patients remaining in the study at 12 weeks. There was no significant change in any of the parameters in either active or placebo group. Hence, nedocromil sodium has not been found to contribute to the management of stable bronchiectasis in this study and larger studies are required to identify more modest effects.
Persistent Identifierhttp://hdl.handle.net/10722/68057
ISSN
2015 Impact Factor: 1.833
2015 SCImago Journal Rankings: 0.638

 

DC FieldValueLanguage
dc.contributor.authorIp, Men_HK
dc.contributor.authorSo, SYen_HK
dc.contributor.authorLam, WKen_HK
dc.contributor.authorShum, Den_HK
dc.date.accessioned2010-09-06T06:00:55Z-
dc.date.available2010-09-06T06:00:55Z-
dc.date.issued1993en_HK
dc.identifier.citationJournal Of Clinical Pharmacy And Therapeutics, 1993, v. 18 n. 5, p. 337-341en_HK
dc.identifier.issn0269-4727en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68057-
dc.description.abstractA double-blind parallel group comparative pilot study was carried out in patients with bronchiectasis to evaluate the anti-inflammatory effect of nedocromil sodium in chronic bronchial infection. Patients were randomized to either a nedocromil sodium metered dose inhaler, 4 mg, four times daily, or placebo for 12 weeks. Clinical symptoms, lung function tests and sputum characteristics of volume, purulence, leucocyte count, neutrophil chemotactic activity and elastolytic activity were evaluated at baseline, after 4, 8 and 12 weeks of the trial. Patients were withdrawn when they had acute infective exacerbation. There were 13 evaluable patients and results were statistically analysed at 8 weeks due to the limited number of patients remaining in the study at 12 weeks. There was no significant change in any of the parameters in either active or placebo group. Hence, nedocromil sodium has not been found to contribute to the management of stable bronchiectasis in this study and larger studies are required to identify more modest effects.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltd.en_HK
dc.relation.ispartofJournal of Clinical Pharmacy and Therapeuticsen_HK
dc.rightsJournal of Clinical Pharmacy and Therapeutics. Copyright © Blackwell Publishing Ltd.en_HK
dc.titleNedocromil sodium in the management of chronic bronchial infectionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-4727&volume=18&spage=337&epage=341&date=1994&atitle=Nedocromil+sodium+in+the+management+of+chronic+bronchial+infectionen_HK
dc.identifier.emailIp, M:msmip@hku.hken_HK
dc.identifier.emailShum, D:shumdkhk@hkucc.hku.hken_HK
dc.identifier.authorityIp, M=rp00347en_HK
dc.identifier.authorityShum, D=rp00321en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-0027437246en_HK
dc.identifier.hkuros8126en_HK
dc.identifier.volume18en_HK
dc.identifier.issue5en_HK
dc.identifier.spage337en_HK
dc.identifier.epage341en_HK
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridIp, M=7102423259en_HK
dc.identifier.scopusauthoridSo, SY=7102397816en_HK
dc.identifier.scopusauthoridLam, WK=7203021937en_HK
dc.identifier.scopusauthoridShum, D=7004824447en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats